... validity of the new model for the analysis of the mechanisms of cartilage destruction by SFB. Both MMP-1, capable of cleaving intact collagen [44], and MMP-3, responsible for the cleavage of other ... inhibition of the caseinolytic activity in zymography by EDTA and lack of inhibition by the serine protease inhibitor phenylmethylsulfonyl fluoride further co...
Ngày tải lên: 09/08/2014, 01:22
... via A 2A and the A 3 adenosine receptors [8,9]. The highly selective A 3 adenosine receptor (A 3 AR) agonist IB- MECA (1-deoxy-1-[6-[[(3-iodophenyl)methyl]amino]-9H-9-yl]- N-methyl-β-D-ribofura-nuronamide) ... 6 Research article Methotrexate enhances the anti-inflammatory effect of CF101 via up-regulation of the A 3 adenosine receptor expression Avivit Ocha...
Ngày tải lên: 09/08/2014, 08:23
Báo cáo y học: "Proteinases in the joint: clinical relevance of proteinases in joint destruction Yvonne Rengel, Caroline Ospelt and Steffen Gay" doc
... the same process, primarily in tissues or cells that do not express cathepsin S. Finally, cathepsin K was found to be Review Proteinases in the joint: clinical relevance of proteinases in joint destruction Yvonne ... therapeutic strategy. They can inhibit the activity and production of MMPs (MMP-1, MMP-3 and MMP-13, and MMP-2 and MMP-9). This family o...
Ngày tải lên: 09/08/2014, 10:21
Báo cáo y học: "Correlating measurements across samples improves accuracy of large-scale expression profile experiments" pps
... were mostly focused on improving accuracy for standalone expres- sion measurements, and largely disregarded the increasing availability of gene -expression profiles representing a diver- sity of phenotypic ... Genome Biology 2009, 10:R143 Open Access 2009Alvarezet al.Volume 10, Issue 12, Article R143 Method Correlating measurements across samples improves accuracy of larg...
Ngày tải lên: 09/08/2014, 20:21
Báo cáo y học: "LMP-420, a small-molecule inhibitor of TNF-alpha, reduces replication of HIV-1 and Mycobacterium tuberculosis in human cell" pps
... Central Page 1 of 9 (page number not for citation purposes) AIDS Research and Therapy Open Access Research LMP-420, a small-molecule inhibitor of TNF-alpha, reduces replication of HIV-1 and Mycobacterium ... Corresponding author Abstract Background: Co-infections of human immunodeficiency virus (HIV) and Mycobacterium tuberculosis (M. Tb) are steadily incr...
Ngày tải lên: 10/08/2014, 05:20
Báo cáo y học: "Dietary restrictions in healing among speakers of Iquito, an endangered language of the Peruvian Amazo" docx
... Jernigan: Dietary restrictions in healing among speakers of Iquito, an endangered language of the Peruvian Amazon. Journal of Ethnobiology and Ethnomedicine 2011 7:20. Jernigan Journal of Ethnobiology ... critically endangered Amazonian language of the Zaparoan family. The study focused on the concept of “dieting” (siyan++ni in Iquito), a practice...
Ngày tải lên: 10/08/2014, 09:21
Báo cáo y học: "Captopril reduces cardiac inflammatory markers in spontaneously hypertensive rats by inactivation of NF-kB" ppsx
... Captopril reduces cardiac inflam- matory markers in spontaneously hypertensive rats by inactivation of NF-kB Journal of Inflammation 2010, 7:21 Miguel-Carrasco et al. Journal of Inflammation ... administered to hypertensive rats, the decrease in mRNA expression of pro -inflammatory markers and the increase in the expression of anti-inflam- matory cytok...
Ngày tải lên: 11/08/2014, 03:20
Báo cáo y học: " Osteolytic bone destruction resulting from relapse of a testicular tumour 23 years after inguinal orchiectomy and adjuvant chemotherapy: a case report" pot
... efficacious therapy was surgical resection of the tumour mass. We report here a case of a late relapse of a germ cell tumour, which occurred 23 years after orchiectomy and following four cycles of ... [4]. Late relapse is defined as a germ cell tumour that appears more than two years after therapy and complete remission [3]. Of the 81 patients trea...
Ngày tải lên: 11/08/2014, 14:20
Báo cáo y học: "Alternative way to test the efficacy of swine FMD vaccines: measurement of pigs median infected dose (PID50) and regulation of live virus challenge dose" docx
... Alternative way to test the efficacy of swine FMD vaccines: measurement of pigs median infected dose (PID 50 ) and regulation of live virus challenge dose. Virology Journal 2010 7:215. Table 2 The results ... is the leader of the study group. DL carried out the experiments and wrote the manuscript. ZJL and PS carried out the animal...
Ngày tải lên: 12/08/2014, 01:21
Báo cáo y học: " Why measure cardiac output" ppt
... with varying degrees of hemodynamic stability would be required. Because any inaccuracy present in the measure of cardiac output by thermodilution reflects not only technical aspects of consistency ... thermodilution measures of cardiac output, if performed correctly and with inspection of the thermal decay profile to identify poor injection runs, give cardiac output values that may v...
Ngày tải lên: 12/08/2014, 19:22
Báo cáo y học: "Bench-to-bedside review: The value of cardiac biomarkers in the intensive care patient" pdf
... between the biomarkers and the severity of the disease, the provision of prognosis, and the ease of performing the test. The use of cardiac biomarkers in the ICU continues to evolve with new findings. ... originally thought. In the intensive care setting, it is important for the user to understand the degree of specificity of these biomarkers...
Ngày tải lên: 13/08/2014, 10:20
Báo cáo y học: "Bench-to-bedside review: The importance of the precision of the reference technique in method comparison studies – with specific reference to the measurement of cardiac output" ppsx
... bias with tight limits of agreement. These Review Bench -to- bedside review: The importance of the precision of the reference technique in method comparison studies – with specific reference to the ... (OD) ultrasound techniques as a measurement of cardiac output. They compared these against ITD cardiac output from the pulmonary artery c...
Ngày tải lên: 13/08/2014, 11:23
Báo cáo y học: " A statistical model for the identification of genes governing the incidence of cancer with age" pptx
... 8 1 2 3 4 5 6 7 8 Time Number of clones AA actual AA fitted Aa actual Aa fitted aa actual aa fitted 1 2 3 4 5 6 7 8 1 2 3 4 5 6 7 8 Time Number of clones AA actual AA fitted Aa actual Aa fitted aa actual aa fitted CD 1 ... 8 0 2 4 6 8 10 12 Time Number of clones AA actual AA fitted Aa actual Aa fitted aa actual aa fitted 1 2 3 4 5 6 7 8 0 2 4 6 8 10 12 Time Number of clones AA actual...
Ngày tải lên: 13/08/2014, 16:21
Báo cáo y học: "Cross-comparison of cardiac output trending accuracy of LiDCO, PiCCO, FloTrac and pulmonary artery catheters" docx
... trending accuracy of LiDCO, PiCCO, FloTrac and pulmonary artery catheters Mehrnaz Hadian 1,3 , Hyung Kook Kim 1 , Donald A Severyn 2 , Michael R Pinsky 1* Abstract Introduction: Although less invasive than pulmonary ... device. Abbreviations CCO: cardiac output by continuous technique; CO: cardiac output; COtd: cardiac output by thermodilution technique; DO 2 :...
Ngày tải lên: 14/08/2014, 07:21