Medical Management of Diabetes and Heart Disease - part 4 docx

... evolution and persistence of thrombosis and the rapidity and extent of lysis of thrombi associated with vascular damage and its repair, overexpression of PAI-1 is likely to exacerbate both devel- opment ... HDL and chylomicrons apo B -4 8 2 64, 000 chylomicrons Necessary for assembly and se- cretion of chylomicrons from the small intestine apo B-100 5 14, 000 VLDL, IDL,...

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... PTCA- and CABG-treated patients even in subgroups of diabetes and three-vessel disease (31). In addition to the randomized trials com- paring PCI and CABG, three large, single-center registries and ... time of restenosis, that is 3 to 4 months post-intervention. For long-term follow-up of 268 Peragallo-Dittko Table 3 Recommendations Regarding Diabetes and Smoking Asses...

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... 10016 tel: 21 2-6 9 6-9 000; fax: 21 2-6 8 5 -4 540 Eastern Hemisphere Distribution Marcel Dekker AG Hutgasse 4, Postfach 812, CH -4 0 01 Basel, Switzerland tel: 4 1-6 1-2 6 1-8 48 2; fax: 4 1-6 1-2 6 1-8 896 World Wide ... Figures 3 and 4 which plot cumulative mortality from coronary heart disease during 24 years of follow-up of a cohort of patients w...

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... (37), and Glut -4 transloca- tion ( 34, 40 43 ). Specifically, activation of PI-3 kinase has been reported to be necessary for insulin-stimulated glucose uptake in rat adipocytes ( 34, 44) , 3T 3- L1 adipocytes ... Report of the expert committee on the diagnosis and classification of diabetes melli- tus. Diabetes Care 2001; 24( suppl 1):S5–S20. 2. Wingard DL, Barrett-Cannor E....

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... J 1995; 14: 42 88 42 95. 54. Didichenko SA, Tilton B, Hemmings BA, Ballmer-Hofer K, Thelen M. Constitu- tive activation of protein kinase B and phosphorylation of p47phox by a membrane- targeted ... 1999; 2 74: 248 96– 249 00. 57. Lawrence JCJ and Roach PJ. New insights into the role and mechanism of glycogen synthase activation by insulin. Diabetes 1997; 46 : 541 – 547 . 58....

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... (IRS-1 and IRS-2), and activation of the phosphoinositol 3′ kinase (PI-3′-K) pathway. On the other hand, cell growth and differentiation are regu- lated primarily by the SHC, GRB-2, and the MAP-kinase ... insulin resistant, and perhaps as many as 25% of overweight/obese individuals are nor- 8 Detection and Diagnosis of Syndromes of Insulin Resistance and of Diabetes...

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... function was age-dependent, with an estimated risk ratio of 4. 2 to develop ischemic heart dis- ease for PCOS women 40 to 49 years of age, and a risk ratio of 11.0 for those 50 to 61 years of age as ... evolution of macrovascu- lar disease, although this prophylactic strategy is utilized by many physicians in the management of patients with type 2 diabetes. In a recent...

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... lev- els of high-density-lipoprotein (HDL) cholesterol, and increased low-density-li- poprotein (LDL) cholesterol, hypertension, and central obesity with an increased waist-to-hip ratio. Many cross-sectional ... regarding ag- gressive medical therapy in the context of state -of- the-art coronary revasculariza- tion. In summary, stenting is feasible in diabetics with favorable proced...

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... 37 management, 54 56 obesity, 47 48 prothrombotic activity, 52– 54 Tokyo, 20 treatment, 143 – 144 type 2 diabetes, macrovascular dis- ease, 22–23 Insulin signaling cascade, 39, 43 45 schematic, 40 Insulin-stimulated ... 239– 242 candidate selection, 233–251 glycemic control, 248 – 249 lipid lowering, 249 –250 method selection, 246 – 247 stents, 242 – 245 vs. CABG, 244 – 246 Myo...

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