Báo cáo y học: "Injury severity and serum amyloid A correlate with plasma oxidation-reduction potential in multi-trauma patients: a retrospective analysis" pptx

... Resuscitation and Emergency Medicine Open Access Original research Injury severity and serum amyloid A correlate with plasma oxidation-reduction potential in multi-trauma patients: a retrospective ... potential (ORP) in assess- ing the amount of oxidative stress in the plasma of criti- cally ill patients and correlating with plasma paraoxonase- a...

Ngày tải lên: 13/08/2014, 23:21

... inhibitors of the caspase cascade. Serum was associated with an increase in cIAP-1 and Bcl-2, anti-apoptotic proteins. Interestingly, serum was also associated with an apparent increase in Bax, ... occasions. SF FCS 1% TGF-β ββ β1 100pM Stauro 1µ µµ µM Bax cIAP1 XIAP Intact PARP Cleaved PARP Intact Caspase3 Cleaved Caspase3 Bcl-2 β ββ β-actin β ββ β-actin β ββ β-actin β ββ β-act...

Ngày tải lên: 12/08/2014, 18:20

... leukocytes using a genomic DNA kit (Qiagen) a ccording to the manufacturer’s instructions. Genotyping was achieved using an assay-on-demand allelic discrimination assay and detection system according ... to participate and is capable of giving informed consent; and (3) individual is a self- reported non-aboriginal Taiwanese, and none of the par- ents and grandparents has abori...

Ngày tải lên: 10/08/2014, 05:21

... structures and TLR ligands, such as araLAM and LPS, and pro-inflammatory cytokines, including IL-1β, TNF-α, GM-CSF and IFN-γ.[16, 22, 37, 38] It is plausi- ble that an advantage in pathogen recognition ... neutrophil and macrophage infiltration and decreased levels of TNF- α and macrophage inflammatory protein-2 (MIP2). [49] In another study using transgenic mice with...

Ngày tải lên: 08/08/2014, 16:23

... olyDoms database, which inte- grates all coding SNPs in human protein domains. Database construction The CMSNP database contains two main datasets, an SNP dataset and an SV dataset, which are ... Malek JA, Manning JM, Antipova AA, Perez DS, Moore MP, Hayashibara KC, Lyons MR, Beaudoin RE, et al: Sequence and structural variation in a human genome uncovered by short-read, massively p...

Ngày tải lên: 09/08/2014, 23:20

... examined other ER stress agents in OASF and RASF. First, we treated cells with tunicamycin, an N-acetyl glycosy lation inhibitor. In RASF, tunicamycin increased autophagy in a similar manner as ... significantly increased at 2 h after treatment with thapsigargin, and reached a maximum after 8 h. In OASF, its expression was sig- nificantly increased at both 12 h and 3 6 h...

Ngày tải lên: 12/08/2014, 11:22

... enzymatically active and inactive chitinases, acidic mammalian chiti- nase (AMCase) and BRP-39 have been shown to be cru- cial in murine models of allergic inflammation. Specifically, BRP-39 and AMCase ... flow cytometer and data analyzed with FlowJo analysis software (TreeStar Inc. and Standford University,PaloAlto,California). The following antibodies were used for flow cytome...

Ngày tải lên: 12/08/2014, 13:22

... believe that the COPD patients in thepresentstudyalsohavefeaturesofremodelingin the small airways and probably also emphysema. Stu- dies evaluating both large and small airways in a well characterized ... beta-agonist inhaler and two had a short-acting antimuscarinic inhaler. In addition, six patients used oral N-acetylcysteine. Each participant gave an informed consent and...

Ngày tải lên: 12/08/2014, 13:22

... respectively. Statistical analysis In initial exploratory data analysis, the distributions of all variables were examined. Means and standard deviations were calculated for normally distributed continuous vari- ables, ... disease was assessed by cardiac computed tomography. Multivariable regression analysis was used to identify pulmonary symptoms and nonpulmonary parameters associated...

Ngày tải lên: 12/08/2014, 14:21

... designed and carried out the study planning, participated in analysis and interpretation of the data, and critically revised the manuscript. All authors have read and approved the final manuscript. Dore ... study included a baseline e xamination and follow- up examinations at approximately 2.7 and 5 years. The research conducted in this manuscript is in compliance with t...

Ngày tải lên: 12/08/2014, 15:22