... shown). Kinetics of membrane binding The kinetics of binding to PL membranes of the zymogen factor X, activated factor X (factor Xa) and the active site inhibited form DEGR -factor Xa as well as the the factor ... Ca 2+ concentration at which half- maximum binding occurs. Kinetics of membrane binding Membrane binding experiments on factor X, factor Xa, DEGR -factor...
Ngày tải lên: 08/03/2014, 23:20
... Expression of the uncoupling protein 1 from the aP2 gene promoter stimulates mitochondrial biogenesis in unilocular adipocytes in vivo Martin Rossmeisl 1 , Giorgio Barbatelli 2 , Pavel Flachs 1 , Petr ... results of the morphometric analysis indicated induction of mitochondrial biogenesis by ectopic UCP1 in the unilocular adipocytes....
Ngày tải lên: 31/03/2014, 15:20
Báo cáo y học: "Differentiation of naive CD4+ T cells towards T helper 2 cells is not impaired in rheumatoid arthritis patients" pps
... 2. Panayi GS, Lanchbury JS, Kingsley GH: The importance of the T cell in initiating and maintaining the chronic synovitis of rheumatoid arthritis. Arthritis Rheum 19 92, 35: 729 -735. 3. Burmester ... tissue-destructive T- cell activity in rheumatoid arthritis (RA). The differentiation of naive CD4 + T cells into memory Th2 cells by IL-7 in comparison with tha...
Ngày tải lên: 09/08/2014, 01:23
Báo cáo y học: "Use of soluble MHC class II/peptide multimers to detect antigen-specific T cells in human disease." pps
... capable of detecting the great majority of the T cells that can respond to peptide in vitro. A final limitation of this technology is probably the techni- cal difficulty in generating particular MHC ... measure of the affinity of the TCR for the MHC/ peptide. Binding of the multimer was shown to be mostly indepen- dent of CD4 [6]. MHC class II/peptide multi...
Ngày tải lên: 09/08/2014, 03:24
Báo cáo y học: "Risk of acute myocardial infarction with nonselective non-steroidal anti-inflammatory drugs: a meta-analysis" ppsx
... terms and text words) relating to NSAIDs (for instance, anti-inflammatory agents, non steroidal anti-inflammatory) and AMI (for instance, myocardial infarction, myocardial ischemia, cardiac ischemia, death) ... colorectal adenomas and carcinomas. Cochrane Database Syst Rev 2004, 2:CD004079. 8. Cryer B, Feldman M: Cyclooxygenase-1 and cyclooxygenase-2 selectivity of widely used nonst...
Ngày tải lên: 09/08/2014, 08:22
Báo cáo y học: "Association of cerebrospinal fluid anti-ribosomal P protein antibodies with diffuse psychiatric/neuropsychological syndromes in systemic lupus erythematosus" pps
... relationship of antibodies to the whole ribosomal P proteins (P0 , P1 , and P2 ) in cerebrospinal fluid (CSF) with diffuse psychiatric/neuropsychological syndromes in systemic lupus erythematosus ... ribosomal P protein epitopes other than the C-terminal 22-amino acid sequence (anti -P EX.C22 ) in cerebrospinal fluid from patients with systemic lup...
Ngày tải lên: 09/08/2014, 10:20
Báo cáo y học: " Importance of spliceosomal RNP1 motif for intermolecular T-B cell spreading and tolerance restoration in lupus" pptx
... illustrating the possible role of RNP1 motif in the initiation of T-B cell spreading pathway (adapted from [13]). Epitopes containing the RNP1 motif (in dark blue) are presented to specific T cells ... spread- ing), then proceeds in an ordered manner to other proteins containing the RNP1 motif, and finally, to proteins that do not contain any RNP1 motif but are...
Ngày tải lên: 09/08/2014, 10:21
Báo cáo y học: "Efficacy of antibiotic therapy for SAPHO syndrome is lost after its discontinuation: an interventional study" pps
... article Efficacy of antibiotic therapy for SAPHO syndrome is lost after its discontinuation: an interventional study Gunter Assmann 1 , Olaf Kueck 2 , Timm Kirchhoff 3 , Herbert Rosenthal 3 , Jan Voswinkel 1 , ... whereas dis- continuation of antibiotic therapy seems to be associated with disease deterioration. In what way a permanent administration of antib...
Ngày tải lên: 09/08/2014, 14:22
Báo cáo y học: "Effect of smoking on lung function, respiratory symptoms and respiratory diseases amongst HIV-positive subjects: a cross-sectional study pptx
... symptoms and respiratory diseases amongst HIV-positive subjects: a cross-sectional study. AIDS Research and Therapy 2010 7:6. Submit your next manuscript to BioMed Central and take full advantage of: ... function (normal/abnormal), respiratory symptom (yes/no), respiratory disease (yes/ no) and sub ject classification (normal lung function and no symptom/abno...
Ngày tải lên: 10/08/2014, 05:21
Báo cáo y học: " Ethnomedicine of the Kagera Region, north western Tanzania. Part 2: The medicinal plants used in Katoro Ward, Bukoba District" doc
... products. The study is an ethnomedical documentation of medicinal plants in Katoro Ward of, Bukoba district, north western Tanzania. Methodology Description of the study site Katoro is a ward within Bukoba ... Medicinal plants used in Katoro ward; Bukoba District. The file contains a list of medicinal plant species, their uses, parts used and m...
Ngày tải lên: 10/08/2014, 09:21
Báo cáo y học: "Impact of concomitant aortic regurgitation on long-term outcome after surgical aortic valve replacement in patients with severe aortic stenosis" potx
... [7]. In conclusion, our data indicate that the preoperative presence and severity of concomitant AR has no influ- ence on long-term postoperative outcome, LV function and functional capacity in patients ... mortality. Conclusion: Our data indicat e that the preoperative presence and severity of concomitant AR has no influence on long-term postoperative outcome, LV func...
Ngày tải lên: 10/08/2014, 09:21
Báo cáo y học: " Risk of malnutrition is associated with mental health symptoms in community living elderly men and women: The Tromsø Study" pdf
... this article as: Kvamme et al.: Risk of malnutrition is associated with mental health symptoms in community living elderly men and women: The Tromsø Study. BMC Psychiatry 2011 11:112. Submit your ... for the association between mental health problems (in four categories) and the risk of malnutrition (combining medium and high risk) in...
Ngày tải lên: 11/08/2014, 15:22
Báo cáo y học: "Risk of incident or recurrent malignancies among patients with rheumatoid arthritis exposed to biologic therapy in the German biologics register RABBIT" pdf
... [Recommendations of the German Society of Rheumatology for therapy with tumor necrosis factor inhibitors. Pharmacotherapy Committee of the German Society of Rheumatology]. [http://dgrh.de/fileadmin/media/ Qualitaetssicherung/Therapie-Empfehlungen/TNF-Blocker_06 .pdf] . ... the original work is properly cited. Research article Risk of incident or recurrent malig...
Ngày tải lên: 12/08/2014, 11:22
Báo cáo y học: " Expression of K2P5.1 potassium channels on CD4+ T lymphocytes correlates with disease activity in rheumatoid arthritis patients" potx
... disease activity parameters during a longitudinal follow-up for six months. Conclusions: Disease activity in RA patients correlates strongly with K 2P 5.1 expression levels in CD4 + T lymphocytes in the ... destruction of multiple joints. The systemic nat- ure of RA causes, next to loss of joint function, substantially decreased quality of life and increased mo...
Ngày tải lên: 12/08/2014, 15:22
Báo cáo y học: "Risk of symptomatic heterotopic ossification following plate osteosynthesis in multiple trauma patients: an analysis in a level-1 trauma centre" pdf
... performed data analysis and interpretation and drafted the manuscript. FH interpreted data and helped drafting the manuscript. PM carried out data analysis. JS has made substantial contributions to acquisition ... intra-cranial injuries. Patients with an almost normal to normal GCS and com- bined anatomical lesions on the CT-scan were classified as head injured patients. Analysis of...
Ngày tải lên: 13/08/2014, 23:21