... evaluate iron deficiency. Most of patients with iron deficiency in, whom gastrointestinal or systemic signs or symptoms are absent have an underlying ga- strointestinal lesion [24]. Idiopathic iron- deficiency ... â Ivyspring International Publisher. All rights reserved. Research Paper Identification of clinical and simple laboratory variables predicting r...
Ngày tải lên: 25/10/2012, 11:18
... PC1 ⁄ 3, PC2 and PC5 ⁄ 6A are targeted to dense core secretory granules by a common mechanism Jimmy D. Dikeakos 1 , Chantal Mercure 1 , Marie-Jose ´ e Lacombe 1 , Nabil G. Seidah 2 and Timothy ... series of maturation steps that include processing of hormone precursors, condensation to form a dense core, and docking at the plasma membrane. Because dense...
Ngày tải lên: 18/02/2014, 16:20
Báo cáo Y học: Loss-of-function variants of the human melanocortin-1 receptor gene in melanoma cells define structural determinants of receptor function doc
... Loss -of- function variants of the human melanocortin-1 receptor gene in melanoma cells define structural determinants of receptor function Jesu ´ sSa ´ nchez Ma ´ s 1 , ... that impairment of signaling through the cAMP cascade occurs in these cells even in the absence of mutations in the coding region of the gene. Finally, our study...
Ngày tải lên: 17/03/2014, 10:20
Báo cáo Y học: Isolation, enzymatic properties, and mode of action of an exo-1,3-b-glucanase from Trichoderma viride doc
... displayed only very low activity against 1,3-1,4-b-glucans, lichenan, and barley glucan, and Fig. 1. SDS/PAGE of the exo-1,3-b-glucanase from T. viride. Lane 1, purified exo-1,3-b-glucanase from ... 4000-fold. The mode of action of the T. viride exo-1,3-b-glucanase in hydrolysis of 1,3-b-oligoglucosides and curdlan is typical of fungal exo-1,3-b-glucanases [17,...
Ngày tải lên: 24/03/2014, 04:21
Báo cáo Y học: Effect of ibuprofen and warfarin on the allosteric properties of haem– human serum albumin A spectroscopic study potx
... Effect of ibuprofen and warfarin on the allosteric properties of haem human serum albumin A spectroscopic study Simona Baroni 1 , Marco Mattu 2 , Alessandro Vannini 2 , Rita Cipollone 2 , ... evidence for the drug-induced shift of allosteric equilibrium (a) of HSA. Keywords: allostery; haem human serum albumin; human serum albumin; ibuprofen;...
Ngày tải lên: 31/03/2014, 23:20
Báo cáo y học: "Risk factors predict post-traumatic stress disorder differently in men and women" ppt
... study. As expected, the women in this study were significantly more depressed than the men. Depres- sion only reached significance in predicting PTSD severity in women but not in men. This finding ... affec- tive disorder significantly predicted PTSD in women, but not in men, whereas pre-existing anxiety disorder pre- dicted PTSD in men, but not in women [13] Negative...
Ngày tải lên: 08/08/2014, 23:21
Báo cáo y học: "Mannose-binding lectin deficiency is associated with early onset of polyarticular juvenile rheumatoid arthritis: a cohort study" pdf
... Previously, Garred and coworkers [23] showed that MBL2 exon 1 variant allele carrier status was associated with early age at onset of RA, which is the adult counterpart of polyarthritis [26]. Garred and ... and low expression of MBL. The influence of the X /Y allele was also determined by studying six 'extended' genotype groups: YA/YA, YA/XA, XA/XA, YA/O, XA/O and...
Ngày tải lên: 09/08/2014, 10:23
Báo cáo y học: "Magnetically retainable microparticles for drug delivery to the joint: efficacy studies in an antigen-induced arthritis model in mice" doc
... article Magnetically retainable microparticles for drug delivery to the joint: efficacy studies in an antigen-induced arthritis model in mice Nicoleta Butoescu 1 , ChristianASeemayer 2 , Gaby Palmer 3,4 , ... tomography scan All animals implanted with a magnet and used either for the in vivo imaging experiment or for the efficacy testing in the...
Ngày tải lên: 09/08/2014, 14:20
Báo cáo y học: "Effects of typical and atypical antipsychotic drugs on gene expression profiles in the liver of schizophrenia subjects" docx
... (FC) and p-values for the genes in each comparison including the typical AP vs. the controls, the atypical AP vs. the controls, and the typical AP vs. the atypical AP. The comparison between the ... increase insulin sensitivity in the liver by attenuating insulin and leptin signaling pathways [55]. It is interesting that one of the main side effects...
Ngày tải lên: 11/08/2014, 17:20
Báo cáo y học: " Mucocele-like tumor and columnar cell hyperplasia of the breast occurring in a morphologic continuum" pptx
... intraductal carcinoma, invasive carcinoma, atypical ductal hyperplasia and hyperplasia of the usual type [2-4]. Most invasive carcino- mas that arise in this setting are of the mucinous type ... declare that they have no competing interests. Columnar cell lesions with atypia (flat epithelial atypia)Figure 3 Columnar cell lesions with atypia (flat epithelial aty- pia)....
Ngày tải lên: 11/08/2014, 23:21
Báo cáo y học: "Perforin, granzyme B, and FasL expression by peripheral blood T lymphocytes in emphysema" pptx
... T lymphocytes, the lasts having increased cytotoxic activity. Because systemic inflammation is also a component of emphysema, we hypothesize that peripheral CD8 + T lymphocytes of emphysematous ... studies have described their state of activation and their cytotoxic potential in the peripheral blood. Perforin, granzyme B, and FasL are cytotoxic molecules used by CD8...
Ngày tải lên: 12/08/2014, 15:21
Báo cáo y học: "Oxygen-sensing mechanisms and the regulation of redox-responsive transcription factors in development and pathophysiology" ppsx
... participates in the maintenance of intracellular protein integrity by reducing their disulfide linkages and regulating their synthesis, thereby acting as an important regulator of cellular sulfhydryl ... in determining cellular fate and the inflammatory process regulated by cytokines [ 36–46,166,164]. Regulation of cytokines by ROS ROS play a crucial role in the in...
Ngày tải lên: 12/08/2014, 18:20
Báo cáo y học: " MicroRNA miR-146a and further oncogenesis-related cellular microRNAs are dysregulated in HTLV-1-transformed T lymphocytes" ppsx
... [42]. Consequently, these microRNAs may contribute to trans- formation of HTLV-1-infected cells, i.e., the pathogenesis of ATLL, by either maintaining differentiation status or actively driving cells towards ... [64,65]. Conceivably, this constitutes an important facet in both viruses' efforts to establish perstistence or their potential to bring about malignant transformation. In...
Ngày tải lên: 13/08/2014, 05:21
Báo cáo y học: "Road traffic accidents and posttraumatic stress disorder in an orthopedic setting in south-eastern Nigeria: a controlled study" doc
... this article as: Iteke et al.: Road traffic accidents and posttraumatic stress disorder in an orthopedic setting in south-eastern Nigeria: a controlled study. Scandinavian Journal of Trauma, Resuscitation ... standards in construction and maintenance of social amenities like roads amongst others. There have been many cases of road traffic accidents (RTAs)...
Ngày tải lên: 13/08/2014, 23:20
Báo cáo y học: "Dietary weight loss and exercise interventions effects on quality of life in overweight/obese postmenopausal women: a randomized controlled trial" doc
... versions will be made available soon. Dietary weight loss and exercise interventions effects on quality of life in overweight/obese postmenopausal women: a randomized controlled trial International ... examine the individual and combined effects of dietary weight loss and/ or exercise interventions on HRQOL and psychosocial factors (depres...
Ngày tải lên: 14/08/2014, 08:21