Báo cáo y học: "Parameter estimation in biochemical systems models with alternating regression" docx

... MA: Biochemical systems analysis. A study of func- tion and design in molecular biology. Reading, MA, Addison- Wesley; 1976:xvii, 379. 4. Voit EO: Computational analysis of biochemical systems: ... show here that alternating regression (AR), applied to S-system models and combined with methods for decoupling systems of differential equations, provides a fast new tool for ide...

Ngày tải lên: 13/08/2014, 23:20

... Bordron A, Dueymes M, Levy Y, Jamin C, Leroy JP, Piette JC, Shoenfeld Y, Youinou PY: The binding of some human antien- dothelial cell antibodies induces endothelial cell apoptosis. J Clin Invest 1998, ... Conti F, Tinghino R, Pal- ladini G, Valesini G: Beta2-glycoprotein I (beta2-GPI) mRNA is expressed by several cell types involved in anti-phospholipid syndrome-related tissue damage. Cli...

Ngày tải lên: 09/08/2014, 01:23

... caused by inherited (germline) mutations of mtDNA. They comprise a wide spectrum of clinical symptoms that arise as a result of dysfunction of the mitochondrial respiratory chain, mostly affecting ... patients with osteoarthritis (OA). More importantly, in RA tissue significantly more of these mutations resulted in non-synonymous amino acid changes than those in tissues of patients w...

Ngày tải lên: 09/08/2014, 07:20

... and draining lymph nodes are significantly increased in mice with TNF and SIA. Our findings are consistent with those in clinical studies dem- onstrating increased VEGF-C expression in RA joints ... neovascularization, inflammatory cell infiltration, and concomitant synovial cell hyperplasia, the volumes of the synovium and synovial fluid increase, resulting in joint swelling and...

Ngày tải lên: 09/08/2014, 10:21

... mutagenesis, in which male mice are treated with the alkylating agent ethinyl- nitrosourea, causing point mutations in sperm DNA. Offspring of these mice carry these mutations. By screening thousands of ... 605497 LEPRE1 Prolyl 3-hydroxylase Osteogenesis imperfecta type VIII 610339 PLOD2 Lysyl hydroxylase-2 Bruck syndrome (osteogenesis imperfecta with 601865 joint contractures) type 2...

Ngày tải lên: 09/08/2014, 10:23

... MTP joint synovial hypertrophy and forefoot bursal hypertrophy (Table 7). This suggests that the pattern of presence of MTP joint synovial hypertrophy and forefoot bursal hypertrophy within the ... Location of forefoot pathology in the RA participants(n (%)) at baseline and twelve months. Legend: SynHy: MTP joint synovial hypertrophy; BurHy: Forefoot bursal hypertrophy. Forefoot Mid...

Ngày tải lên: 10/08/2014, 21:24

... neurology. HMZ is a neurology trainee. NAA is an intern at the department of internal medicine and neurology. Competing interests The authors declare that they have no competing interests. Received: ... bilirubin 0.8 m g/dL; aspartate transaminase 21 u/L; alanine transaminase 19 u/L; alka- line phosphatase 190 u/L; serum total protein 7.3 g/dL; serum albumin 4.4 g/dL; thyroid stimulating horm...

Ngày tải lên: 10/08/2014, 23:22

... Ade- nosine deaminase activity in the diagnosis of tuberculous peritonitis. Gut 1986, 27(9):1049-53. 11. Hillebrand DJ, Runyon BA, Yasmineh WG, Rynders GP: Ascitic fluid adenosine deaminase insensitivity ... citation purposes) Background In industrialised countries, tuberculosis increasingly occurs in the immigrant population and in patients with acquired immune deficiency syndrome...

Ngày tải lên: 11/08/2014, 11:20

... Tayel SM, Abulhassan SA, Murthy DS: Trisomy 18 in Kuwait. Int J Epidemiol 1999, 28:711-716. 5. Ulrik M, Schioler V, Christensen F, Wolny E, Edeling CJ: Anenceph- aly in trisomy 18 associated with ... hydrocephalus in an Egyptian baby with trisomy 18: a case report Kotb A Metwalley 1 , Hekma S Farghalley 2 and Alaa A Abd-Elsayed* 3 Address: 1 Department of Pediatrics, Faculty of M...

Ngày tải lên: 11/08/2014, 17:21

... Chesney RW, Fink J, Hutchison HT: Myopa- thy and cystine storage in muscles in a patient with nephro- pathic cystinosis. N Engl J Med 1988, 319:1461-1464. 4. Dixit MP, Greifer I: Nephropathic cystinosis ... (LV) is increasingly being recognized as a distinct entity with a significant associated morbidity and mortality; however, definitions are still being debated. A diagnosis can be m...

Ngày tải lên: 11/08/2014, 19:21