Báo cáo y học: "Stochastic modeling of oligodendrocyte generation in cell culture: model validation with time-lapse data" pdf

... Central Page 1 of 8 (page number not for citation purposes) Theoretical Biology and Medical Modelling Open Access Research Stochastic modeling of oligodendrocyte generation in cell culture: model validation ... transformation into terminally differenti- ated oligodendrocytes. This model is widely applicable to other in vitro cell systems. The precursor cell that g...

Ngày tải lên: 13/08/2014, 23:20

... manu- ally and most polymorphisms were subsequently con- firmed by independent genotyping. Genotyping SNP genotypes were determined using the Sequenom MassARRAY MALDI-TOF system. The system analyzes allele-specific ... Biology, Lund University, Lund, Sweden, 4 The National Institute of Environmental Medicine, Karolinska Institutet, Solna, Sweden and 5 Department of Otorhinolaryngology,...

Ngày tải lên: 12/08/2014, 15:21

... the action of sodium metabisulphite on mucociliary transport in a frog palate epithelial injury model, hypothesizing that it may be useful for the study of mechanisms of airway injury. Sodium ... in airway injury and remodeling [7,8] and in cell- signaling pathways [14]. Materials and Methods Development of a frog palate injury model A fresh frog palate was prepared as prev...

Ngày tải lên: 12/08/2014, 18:21

... containing 10 µg/mL Leu- peptin, 20 µg/mL Aprotinin, 25 µM p-nitrophenyl guanid- inobenzoate (pNGb). After a ten minute incubation in lysis buffer at 4°C, the cell lysate was clarified by centrifu- gation ... sustained inhibition of HIV- 1 replication was obtained in both acutely and chronically infected macrophages by removing the overt production of peroxynitrite. The effect of...

Ngày tải lên: 13/08/2014, 05:22

... 1 A 23-year-old man was severely injured in a car accident and had multiple trauma, with an injury severity score (ISS) of 50 and a head abbreviated injury score (AIS) of 5.  ree days later ... zhoutom1978@hotmail.com 1 Department of Emergency Medicine, Second A liated Hospital, Zhejiang University, School of Medicine, Research Institute of Emergency Medicine, Zhejiang Un...

Ngày tải lên: 14/08/2014, 08:21

... C-terminal domain illustrates two features. One is a lining-up of basic residues (Arg405, Lys407, Lys413, Lys414, Lys422, Lys428, and Lys430) oriented in the same direction with the heparin-binding ... peptide sequence containing Trp393 and Trp394 Table 1. Heparin affinity of C-terminal domain of LPL. In vitro product of C-terminal domain Heparin affinity NaCl ( M ) Wild type 0.48 K...

Ngày tải lên: 21/02/2014, 15:20

... particularly valuable when judging predictive power over poorly-trained material, specifically Italian sentences in a domain of discourse different from that of the training corpus. Using training ... reliably obtained from the strongest model in the chain, the algorithm will then bacl~-off to the next weakest model, and proceed recursively along the chain of elementary mod...

Ngày tải lên: 01/04/2014, 00:20

... domain,” in Bayesian Interference in Wavelet Based Models, vol. 141 of Lecture Notes in Statistics, pp. 291–308, Springer-Verlag, New York, NY, USA, 1999. [22] E. P. Simoncelli, Modeling the joint ... level in each temporal detail frame in one packet. We further analyze the in uence of losing a packet at dif- ferent spatiotemporal levels in each one of these settings and t...

Ngày tải lên: 23/06/2014, 01:20

... number of modeling choices and careful statistical analysis: using a repre- sentation that allows variability in seed region binding, including non-canonical seed base pairing; incorporat- ing a ... in the vicinity of the target site. In addition, a number of RNA-binding motifs have been linked to modulating microRNA-med iated regulation [35]. Finally, the balance between the ab...

Ngày tải lên: 09/08/2014, 20:22

... effects of lipoatrophy on HRQOL. The results of the analysis of the utility values for patients with and without evidence of lipoatrophy are provided in Table 2. Lipoatrophy may increase cost of care ... Quality of Life (HRQOL) in HIV- infected individuals [21]. The incidence of lipoatrophy can be attributed to use of t hymidine analogues as NRTIs. In the ACTG 5142 the...

Ngày tải lên: 13/08/2014, 11:22