Báo cáo y học: " Binary gene induction and protein expression in individual cells" pptx

... observe binary, hybrid and graded protein expression. Protein expression histograms of β -gal, Luc and GFP In examining different mode of gene induction, several reporter genes have been used. To investigate ... of gene expression histograms for binary and graded modes of gene inductionFigure 1 Schematic representation of gene expression histograms for binary...

Ngày tải lên: 13/08/2014, 23:20

... these cytokine genes. The investiga- tion of gene- gene-interactions seems essential given our understanding of the complex interplay between various cytokines in each others regulation. Finally, ... relevance since many of the cytokine genes are found in chromo- somal clusters [31]. Genetic variants within and between different cytokine genes are therefore likely to be in strong lin...

Ngày tải lên: 13/08/2014, 13:22

... First, avoidance of often ineff ective and delayed interventions in critically ill patients with severe acute kidney injury [3] and early CRRT as applied in the RENAL (Randomised Evaluation of ... averaging CRRT dose over time, studies in this area obfuscate the benefi ts of appro- priately higher dose therapy early in the course of illness, potentially misguiding clinicians i...

Ngày tải lên: 14/08/2014, 08:21

... as regulating neurotrophin expression [29], have recently also Figure 4 NGF staining by flow cytometryNGF staining by flow cytometry. PBMC of (a) healthy controls (HC) and (b) synovial fluid mononuclear ... auto-phosphorylation and subsequently the activation of both phospholipase PLCγ and protein kinase C, which in turn activates the mitogen-acti- vated protein kinase pathway i...

Ngày tải lên: 09/08/2014, 14:21

... expression of the glycoprotein s, basolateral sorting was shown to depend on cytoplasmic tyrosine-based targeting motifs: Y 525 in the F protein and di-tyrosine Y 28/29 in the G protein. Mutations in the ... study) Foci formation in NiV-infected polarized cell monolayers yes yes Glycoprotein distribution in NiV-infected polarized cells F protein bipolar bipolar G prote...

Ngày tải lên: 12/08/2014, 02:20

... CD70 and CD11a expression in lupus T cells by recruiting the histone methyltransferase SUV39H1 Ming Zhao, Xiaoyan Wu, Qing Zhang, Shuangyan Luo, Gongping Liang, Yuwen Su, Yixin Tan , Qianjin Lu * Abstract Introduction: ... histone hypoacetylation and DNA hyper- methylation and consequently to the suppression of tar- get gene expression [10]. In a previous study, we found that...

Ngày tải lên: 12/08/2014, 15:22

... released by mast cells in response to IgE cross-linking [10] indicating a role in allergic inflammation. On the contrary, the IFN- γ-inducible CXCR3 ligands and some CCR5 ligands are increased in autoimmune ... and thus we conclude that pollen allergic, asymptomatically pollen sensitized and healthy individuals cannot be distin- guished by means of chemokine receptors expression...

Ngày tải lên: 13/08/2014, 13:22

... further study of the two cell lines could help identify some of the factors involved in the mechanism of imprinting. Interestingly, another study found that CPA4 was imprinted in many fetal tissues ... novel imprinted genes and delineated regions of imprinted expression surrounding annotated imprinted genes. More subtle parent-of-origin-dependent expression, or partial imprinting, co...

Ngày tải lên: 09/08/2014, 22:24

... antibody array. In this study, antibody arrays findings suggested significantly increased expression of IL-6 and -13 and L-selectin pro- teins and significantly decreased IL-2 protein in lung homogenates ... significantly increased IL-6 and GM-CSF proteins and decreased IL-2 protein expression in lung tissue homogenates using suspension bead array. These findings corre...

Ngày tải lên: 11/08/2014, 08:21

... genotypes investigated were independently associated with mortality. Background Clinical significance of gene polymorphisms involved in haem ostatic pathways including coagulation, fibrinolysis, platelet ... abbreviations used ACE-ins/del: angiotensin I-converting enzyme insertion/deletion; CABG: coronary artery bypass grafting surgery; CAD: coronary artery disease; CK-MB: creatine kinase...

Ngày tải lên: 10/08/2014, 09:22