Báo cáo y học: " Volume of the effect compartment in simulations of neuromuscular block" doc

Báo cáo y học: " Volume of the effect compartment in simulations of neuromuscular block" doc

Báo cáo y học: " Volume of the effect compartment in simulations of neuromuscular block" doc

... in muscle, including the synaptic spaces, as a single pharmacokinetic compartment. The volume of the inter- stitial space in muscle defines the volume of this compartment. Due to the presence of the ... pharmacoki- netic/pharmacodynamic model describing quantitatively the influence of plasma protein binding, tissue binding, and receptor binding on the potenc...
Ngày tải lên : 13/08/2014, 23:20
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Báo cáo Y học: ORF6 from the clavulanic acid gene cluster of Streptomyces clavuligerus has ornithine acetyltransferase activity potx

Báo cáo Y học: ORF6 from the clavulanic acid gene cluster of Streptomyces clavuligerus has ornithine acetyltransferase activity potx

... ring closure catalysed by b-lactam synthetase (BLS/ORF3) [6–8]. Hydroxylation by clavaminic acid synthase (CAS/ORF5), followed by hydrolysis of the guanidino side-chain catalysed by proclavaminate ... N-acetylarginine, followed by incubation with CAS and appropriate cofactors resulted in the formation of 3-hydroxy-N-acetylarginine, as detected by HPLC analysis. The observation tha...
Ngày tải lên : 08/03/2014, 22:20
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Báo cáo y học: "What is the clinical and ethical importance of incidental abnormalities found by knee MRI" docx

Báo cáo y học: "What is the clinical and ethical importance of incidental abnormalities found by knee MRI" docx

... read the MRI scans: they are not usually trained in musculoskeletal radiology or MRI beyond the measurements they perform. The researcher is obliged to put the health of the participant above the ... important given the increasing use of MRI in the investigation of OA by researchers trained for the particular task but not in radiology. This issue has only recentl...
Ngày tải lên : 09/08/2014, 10:22
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Báo cáo y học: "Ultrasound has the potential to detect degeneration of articular cartilage clinically, even if the information is obtained from an indirect measurement of intrinsic physical characteristics" pdf

Báo cáo y học: "Ultrasound has the potential to detect degeneration of articular cartilage clinically, even if the information is obtained from an indirect measurement of intrinsic physical characteristics" pdf

... separately. We therefore consider that the signal intensity obtains information including these parameters. We do not disregard measuring the intrinsic physical charac- teristics. Indeed, the signal intensity ... ultrasound system obtains indirect information on intrinsic physical characteristics of living human articular cartilage in vivo. We recognize that the ultrasound signal...
Ngày tải lên : 09/08/2014, 14:21
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Báo cáo y học: "Insight into the molecular requirements for pathogenicity of Fusarium oxysporum" pdf

Báo cáo y học: "Insight into the molecular requirements for pathogenicity of Fusarium oxysporum" pdf

... involved in pathogenicity: first, the isolation of the original insertional mutant carrying a muta- tion in or close to the ORF of this gene; and second, the veri- fication of the pathogenicity phenotype ... respectively. FOXG_09637 encodes a hypothetical protein of 387 amino acids with no known domains. FOXG_02054 encodes a hypothetical pro- tein of 156 amino acids co...
Ngày tải lên : 14/08/2014, 21:20
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Báo cáo khoa học: Geraniol dehydrogenase, the key enzyme in biosynthesis of the alarm pheromone, from the astigmatid mite Carpoglyphus lactis (Acari: Carpoglyphidae) docx

Báo cáo khoa học: Geraniol dehydrogenase, the key enzyme in biosynthesis of the alarm pheromone, from the astigmatid mite Carpoglyphus lactis (Acari: Carpoglyphidae) docx

... absence of the probable initiator methionine in the native enzyme may be due to the N-terminal processing commonly observed in eukaryotic proteins [35]. Our phylogenetic analyses of the MDR family ... residues (Cys48, His75, and Cys179) and four cysteine residues (Cys105, Cys108, Cys111, and Cys119) in Car. lactis GeDH may serve as catalytic and noncatalytic zinc- binding si...
Ngày tải lên : 16/03/2014, 06:20
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Báo cáo y học: " Psychoeducation and the family burden in schizophrenia: a randomized controlled trial" docx

Báo cáo y học: " Psychoeducation and the family burden in schizophrenia: a randomized controlled trial" docx

... likely benefits of the medicine, adherence to treat- ment, the importance of follow-up and information regarding prognosis. The intervention emphasises the role the family can play in helping the ... schizophrenia. Patients included in the study ranged in age between 18 and 45 years and had a history of two or more relapses during the course of their illness desp...
Ngày tải lên : 08/08/2014, 23:21
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Báo cáo y học: "A proinflammatory role for Fas in joints of mice with collagen-induced arthritis" docx

Báo cáo y học: "A proinflammatory role for Fas in joints of mice with collagen-induced arthritis" docx

... inflammation/joint destruction in DBA-lpr/ lpr mice in spite of the same clinical score as that of control mice. The proinflammatory cytokines including TNF-α and IL-6 have been intensively investigated ... study, we attempted to evaluate the role of the Fas cell-death pathway in the pathogenesis of CIA by generat- ing DBA/1J mice with a mutation of the Fas gene (D...
Ngày tải lên : 09/08/2014, 01:23
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Báo cáo y học: " ESPECTRA: Searching the Bipolar Spectrum in Eating Disorder patients" pps

Báo cáo y học: " ESPECTRA: Searching the Bipolar Spectrum in Eating Disorder patients" pps

... are consiste nt in the literature, the expansion of the borders of the condition remains controversial [2]. The use of broader definitions results in a direct increase in the prevalence of the disorder. ... [29]. The participants shall be evaluated with the diagnos- tic instruments and symptoms rating scales without any kind of intervention. All assessors had...
Ngày tải lên : 11/08/2014, 15:22
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Báo cáo y học: " Fibrocytes and the tissue niche in lung repair" docx

Báo cáo y học: " Fibrocytes and the tissue niche in lung repair" docx

... [52-54]. Fibrocytes in the lumen of the airway After the fibrocytes have entered the tissue, the fibro- cytes can differentiate into other cell type s and/or con- tinue to migrate to the lumen of the airway. ... respectively) [45,46]. The tissue process starts with lympho cyte infil- tration in the submucosa and injury of the mucosa and epithelial cell layer, and...
Ngày tải lên : 12/08/2014, 13:22
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