Báo cáo y học: " Review of "Systems Biology in Practice" by Edda Klipp, Ralf Hertwig, Axel Kowald, Christoph Wierling and Hans Lehrach" docx

... Central Page 1 of 2 (page number not for citation purposes) Theoretical Biology and Medical Modelling Open Access Book review Review of "Systems Biology in Practice" by Edda Klipp, Ralf Hertwig, ... three main facets of systems biology as it stands today (metab- olism, signal transduction and gene expression), but it also includes brief surveys of th...

Ngày tải lên: 13/08/2014, 23:20

... study of vaccines has captured the attention of the biomedical and public communities for the past hundred years, largely because vaccines play a key role in affecting lifespan and well being, ... economics. A positive trend in the field of vaccinology has been inspired by recent major breakthroughs in the fields of molecular biology, physiology, genomics, proteomics, an...

Ngày tải lên: 12/08/2014, 04:21

... evalu- ation of arthritis (day 14 of AIA). Hematoxylin-eosin stained knee sec- tions were evaluated blindly by grading of inflammation (infl.; cell exudate or infiltrate, hyperplasia) and joint destruction ... in a subgroup of patients with RA accompanied by a massive infiltration of inflammatory cells [8]. In addition, STAT-1 expression has been shown in T and B lymp...

Ngày tải lên: 09/08/2014, 07:20

... disfavored by using ionising radiation and by the inability to visualise soft tissue changes. We recently published data on the reliability of erosion volume measurements on CT and MRI in RA metacarpophalangeal joints, ... volumes by CT and MRI, a very high intramodality and a high intermodality agreement was reached, applying both to individual erosion volume and persons&...

Ngày tải lên: 09/08/2014, 10:23

... themselves capable of triggering TLR4 signaling by trasducing pro- duction of proinflammatory markers in macrophages, adipocytes, and liver leading to insulin resistance. Insu- lin resistance is a main pathological ... blunting of TF diet- induced weight gain, hyperinsulinemina, and hyperglyce- miainmicewithlossoffunctionmutationinTLR4, our results in this study do not directl...

Ngày tải lên: 11/08/2014, 03:20

... themselves capable of triggering TLR4 signaling by trasducing pro- duction of proinflammatory markers in macrophages, adipocytes, and liver leading to insulin resistance. Insu- lin resistance is a main pathological ... blunting of TF diet- induced weight gain, hyperinsulinemina, and hyperglyce- miainmicewithlossoffunctionmutationinTLR4, our results in this study do not directl...

Ngày tải lên: 11/08/2014, 06:22

... application of essential oils on the accumulation of neutrophils in inflammatory sites in skin of mice. Methods: Inflammation with accumulation of inflammatory cells was induced by injection of curdlan, ... inflammatory response induced by intradermaly injected curdlan (0.5 mg/50 µl), was investigated first by using two parameters, the MPO value of skin homoge- nates an...

Ngày tải lên: 11/08/2014, 08:21

... products by our study population during both study years were multivitamins (54% in 2002 and 57% in 2009), proteins (47% and 38%) and vitamin C (28% and 24%). These findings are in line with literature ... Department of Physiology University of Turku, Kiinamyllynkatu 10, 20520 Turku, Finland Full list of author information is available at the end of the article Heikkin...

Ngày tải lên: 11/08/2014, 23:21

... 219 Heinrichs and Look 219.5 Genome Biology 2007, 8:219 Genome Biology 2007, 8:219 Minireview Identification of structural aberrations in cancer by SNP array analysis Stefan Heinrichs and A Thomas ... change, loss of heterozygosity and UPD and to delineate both minimally deleted and minimally amplified regions. Thus, SNP array studies can pinpoint critical structurally a...

Ngày tải lên: 14/08/2014, 07:22

... between LinJ23_V3.0350 and Lin23_V3.0360, and between LinJ23_V3.0380 and Lin23_V3.0390 (Figure 5a). Interestingly, similar repeats of 574 bp with 91% identity were found at the same position in the ... wild-type parent cells. The DNA microarrays were first validated by hybridizing flu- orescently labeled digested DNA of wild-type L. major and L. infantum cells. The arrays were...

Ngày tải lên: 14/08/2014, 20:22