Báo cáo y học: " Volume-based non-continuum modeling of bone functional adaptation" pot

... upon perturbation. Such dynamical models essentially consist of a mathematical function that governs the transitions of the state of a gene regulatory network over time. Typically, dynamical models of mRNA concentrations consist ... highly noisy form requiring reverse engineering [31]. A n additional chal- lengeofsystemsbiologyistobeabletomodelsystems precisely enough that they can pr...

Ngày tải lên: 09/08/2014, 22:23

... Results of bone functional adaptation. The color bar shows percentage of actual bone density against maximum bone density, which is 1.74 g/cm 3 . The density of bone structure is not indicated by ... Results of bone functional adaptation. The color bar shows percentage of actual bone density against maximum bone density, which is 1.74 g/cm 3 . The density of...

Ngày tải lên: 13/08/2014, 22:22

... Char- acterization of genetic and phenotypic diversity of invasive nontypeable Haemophilus influenzae. Infect Immun 2005, 73:5853-5863. 11. Shen K, Antalis P, Gladitz J, Sayeed S, Ahmed A, Yu S, Hayes J, ... Cliffs, New Jersey: Prentice Hall; 1988. 45. PHYLIP (Phylogeny Inference Package) [http://evolu tion.genetics.washington.edu/phylip.html] 46. Felsenstein J: PHYLIP (Phylogeny Inferen...

Ngày tải lên: 14/08/2014, 07:21

... depends not only on the probabil- ity that it is occupied by monomeric X but also on the proba- bility that it is occupied by XY. Calculating the probability of occupancy by the XY dimer requires ... experimentally, for example by binding site selection [29] or by computa- tional analysis of co-regulated genes [2,30,31], or by a combi- nation of selection and computational analysis [23]...

Ngày tải lên: 14/08/2014, 14:22

... chemical synthesized [13, 14]. The most commonly used is known as T-1095 (3-(benzofuran-5-yl)-2',6'-dihydroxy-4'-methylpropio- phenone 2'-O-(6-O-methoxycarbonyl-β-D-glyco- pyranoside) ... Med. Sci. 2007, 4 137 tory effect of thioglycoside I (phenyl-1’-thio-β-D glucopyranoside) on hSGLT2 and thioglycoside VII (2-hydroxymethyl-phenyl-1’-thio-β-D-galactopyranosi de)...

Ngày tải lên: 26/10/2012, 10:04

... However, this may be missing the point. The unfolding story of the effects of statins on bone, inflammation, and the cholesterol synthetic pathway is intriguing and points the way to future work. ... statins designed for their effects on hepatic synthesis of cholesterol seem to have biological effects on bone. Only 5% of ingested statins may finally reach the peripheral circu- lati...

Ngày tải lên: 09/08/2014, 03:24

... the synovial tissue. Hyperpla- sia of the synovial lining layer, infiltration of mononuclear cells into the sublining layer, activation of fibroblast-like synovio- cytes and the production of catabolic ... and immunohistochemistry. Activity of arthritis was determined by routine parameters for systemic inflammation, by histological scoring of synovitis and by semiquantitative RT-P...

Ngày tải lên: 09/08/2014, 07:20

... expression of ALP, OCN, OPN, and the alpha chains of collagen type I in OA observed from this study suggests support of the hypothesis of increased OB biosynthetic activ- ity, as postulated by Dequeker ... ani- mal models of a change in the density and metabolism of ALP = alkaline phosphatase; BMD = bone mineral density; BS/BV = specific surface of bone; BS/TV = bone surfac...

Ngày tải lên: 09/08/2014, 08:23

... pathogenesis of various chronic inflammatory diseases, including asthma and allergy [23,24]. In addition, NF-κB plays a key role in the mortality of sepsis [25]. Thus, repression of NF-κB activity by antidepressants ... respectively), lym- phocytes (by 70% and 33%, respectively), neutrophils (by 72% and 38%, respectively) and eosinophils (by 97% and 60%, respectively), while desipramine...

Ngày tải lên: 12/08/2014, 15:20

... 2.9%) was measured by flow cytometry, as depicted in Figure 1C. Vv parenchyma Sum of the points on parenchyma Sum of the to = ttal points Respiratory Research 2008, 9:25 http://respiratory-research.com/content/9/1/25 Page ... leuke- mic, bone marrow and cord blood cells. Leuk Res 2006. 32. Plett PA, Frankovitz SM, Orschell-Traycoff CM: In vivo trafficking, cell cycle activity, and engra...

Ngày tải lên: 12/08/2014, 15:21