Báo cáo y học: "A mathematical model for LH release in response to continuous and pulsatile exposure of gonadotrophs to GnRH" ppt

... studies. Results In Figure 1, we compare the amounts of LH released in 5 minute intervals in the original model and the present model in response to continuous administration of 5 nM GnRH. In both models ... Regulation of luteinizing hor- mone release by pulsatile and continuous administration of gonadotropin-releasing hormone to superfused rat and...

Ngày tải lên: 13/08/2014, 22:22

... mathematical model for the adenylosuccinate synthetase reaction involved in purine biosynthesis Evgeniya A Oshchepkova-Nedosekina* and Vitalii A Likhoshvai Address: Institute of Cytology and Genetics ... Wyngaarden and Greenland [6] proposed that ASUC is a competitive inhibitor of both IMP and ASP, and GMP is a competitive inhibitor of both IMP and GTP. Theoretical...

Ngày tải lên: 13/08/2014, 16:21

... pathways for biofilm formation. Therefore, the aim of the present study is to build a network model of biofilm formation in E. coli K -12, to identify clusters and regulators during biofilm formation ... qualitative continuous model of cellular auxin and brassinosteroid signaling and their crosstalk. Bioinformatics 2011, 10:1404-12. 16. Franke R, Theis FJ, Klamt S: F...

Ngày tải lên: 13/08/2014, 16:20

... optimising prophylaxis. It may also be used to inform guidance and to help clarify the justifi- cation of funding and reimbursement for palivizumab within health services. Finally, this study has ... 9 of 10 (page number not for citation purposes) The model could be realised as a working tool in a variety of formats to optimise its applicability to an individual coun...

Ngày tải lên: 12/08/2014, 14:20

... assigned to the outside. This technique yields n level sets functions Y= {Y 1 , Y 2 , Y n } corresponding to above n aligned training shapes. From the standpoint of QTL mapping, we treat Y= {Y 1 , Y 2 , ... of QTL mapping, we treat Y= {Y 1 , Y 2 , , Y n } as the multiple phenotypic traits of n indivi- duals. For a progeny i (i = 1, 2, , n), we have Y yy y yy y...

Ngày tải lên: 13/08/2014, 16:20

... multi-dimensional models. A host of mathematical modelling techniques has been proposed to model biofilms, including stochastic individual based models, stochastic cellular automata models, and a variety of ... hybrid individual-continuum model of [11], the hydrogel model of [20], and the diffusion-reaction model [27]. For our study we bui ld on the prototype biofilm...

Ngày tải lên: 13/08/2014, 16:20

... "beats," in individual cells. However, like other TTO models of circadian rhythms, it is important to establish that the inherent stochasticity of the protein binding and unbinding does not invalidate ... first in a mathematically rigorous way. Numerical results for both scenarios are presented and compared. Conclusion: Our model proves to be robust to the stoc...

Ngày tải lên: 13/08/2014, 16:21

... pharmacotherapy by maximizing the potency and minimizing the toxicity of the drug [7], whereas drug administration at an inappropriate body time can induce more severe side effects [8]. In practice, body-time- dependent ... for circadian rhythms. In a mapping study of 196 F 2 hybrid mice, Shimomura et al. [24] detected 14 interacting QTL that contribute to the variation of rh...

Ngày tải lên: 13/08/2014, 16:21

... understanding of the cellu- lar events leading to VNH formation. For simplicity, we have conglomerated all cytokines and cell types into one category, giving equal importance to all cytokines and ... flow causes the vein to hypertrophy so that it can be used for repeated needle insertions. A graft connects an artery to a vein by using a synthetic tube of ePTFE, usually in...

Ngày tải lên: 13/08/2014, 16:21

... Institute, University of Florida, Gainesville, FL 32611, USA and 3 Department of Operation Research and Financial Engineering, Princeton University, Princeton, NJ 08544, USA Email: Kiranmoy ... to uncon- trolled cellular proliferation. This model is defined by two key parameters, carrying capacity (K) and intrinsic growth rate (r). Thus, by estimating genotype-specific differe...

Ngày tải lên: 13/08/2014, 16:21