Báo cáo y học: "Regulatory role of E-NTPase/E-NTPDase in Ca2+/Mg2+ transport via gated channel" doc

... purposes) mechanisms may result in a rise in [Mg 2+ ] i , impairing the contractile machinery of the myocardium [34]. Gramicidin S inhibits total Mg 2+ efflux in the myocar- dium, while epinephrine restores ... activity. Conversely, deglycosylation might impair the E-type nucleotidase activity by weakening the monomer-monomer interac- tion and altering the tertiary and quaternary str...

Ngày tải lên: 13/08/2014, 22:22

... overproduction. Importantly, IL-5 is not only produced by CD4 + T lym- phocytes, but also CD8 + T lymphocytes, as well as CD34 + cells. The initial development of eosinophilia is induced in a complex way, including ... local allergen-induced eosinophilic inflammation. Since bone marrow (BM) responses are intricately involved in the induction of airway eosinophilia, we hypothesized t...

Ngày tải lên: 12/08/2014, 16:20

... & Penner-Hahn, J.E. (1998) Characterization of the zinc binding site in methionine synthase enzymes of Escherichia coli – the role of zinc in the methylation of homocysteine. J. Am. Chem Soc. 120, 8410–8416. 15. ... to ligation of the thiol group of coenzyme M. Mutations in His237 or Cys239, which are proposed to be involved in ligating zinc, resulted in an over 90...

Ngày tải lên: 17/03/2014, 23:20

... allergy. factors influencing development of the microbiota. Ann Med 1999, 31(4):288-92. 15. Kalliomaki M, Isolauri E: Role of intestinal flora in the develop- ment of allergy. Curr Opin Allergy Clin ... The role of the intestinal microflora for the development of the immune system in early childhood. Eur J Nutr 2002, 41(Suppi 1):I32-7. 18. Penders J, et al.: Molecular finger...

Ngày tải lên: 08/08/2014, 21:20

... consequently lead to increasing inter- est in the role of osteoclasts in local bone erosion that is driven by the hypothesis that synovial pannus makes use Review The role of osteoprotegerin in arthritis Georg ... Collagen-induced arthritis Species Rat Mouse Rat Dose 1 mg/kg/day 6.4 mg/kg/day 3 mg/kg/day Start Onset of symptoms Onset of symptoms Onset of symptoms Duration...

Ngày tải lên: 09/08/2014, 01:23

... an inflammatory challenge by altering production of proinflammatory and anti-inflammatory cytokines and may also affect cytokine signaling by a variety of mechanisms, including induction of SOCS-3 ... whereas in processes involving innate immunity, anti-inflammatory effects of leptin are prevalent. However, it is difficult to elucidate the role, if any, of leptin during inflammat...

Ngày tải lên: 09/08/2014, 08:22

... and binding-positive may be much more valid compared with the edges inferred by only either of perturbation or binding assay, 70 perturbation and binding positive edges appear to be highly reliable ... TFs in HepG2 cells, binding-positive edges constitute 75% of the perturbation-positive edges, suggesting that the filtering by TRF binding data obtained in ChIP assay may enrich the sig...

Ngày tải lên: 09/08/2014, 20:20

... parental strain (0.49 μg/ml), a fact suggest ing a role of ygfZ involved in the degrada- tion of plumbagin. YgfZ and SodA independently required for resolving plumbagin toxicity Since both ygfZ and ... been Figure 6 Analysis of critical residues in the fingerprint region of YgfZ. (A) Inhibition zone assay for the plumbagin-countering activity of amino acid-substituted YgfZ. Th...

Ngày tải lên: 10/08/2014, 05:21

... of surgery in a trimodality treatment in SCLC. The study included 95 patients, the majority being in stages I and II. Patients were divided in two groups. Group I received surgery followed by ... adjuvant, mainly platin doublets and anthracycline based, modern chemo- therapy protocols. Group II had definitive surgery follow- ing neoadjuvant chemotherapy which continued postoperative...

Ngày tải lên: 10/08/2014, 10:20

... attempts an intervention, organizational mem- bers may already be conversing in ways that improve sensemaking and learning, or they may be conversing in ways that inhibit sensemaking and learning. The ... greatly in its novelty, ranging from the reinforcement of old beliefs or strengthening existing relationships and power structures to completely innovative ideas existing in the mi...

Ngày tải lên: 11/08/2014, 05:21