Báo cáo y học: "Role of selective V2-receptor-antagonism in septic shock: a randomized, controlled, experimental study" pot
... ST each) without significant differences among groups. Laboratory variables of organ function and arginine vasopressin plasma levels Alanine aminotransferas e and aspartate aminotransferase activity ... placebo; c P < 0.05 versus baseline; n = 7 each. ALT, alanine aminotransferase; AST, aspartate aminotransferase; AVP, arginine vasopressin. Figure 3 Arterial base excess (a) and arterial...
Ngày tải lên: 13/08/2014, 21:21
... to have a history of cardiac disease if they had prior or current ischemic heart disease (angina or myocardial infarction) or cardiac surgery. Echocardiography Transthoracic echocardiography and ... Emergency Physicians; Canadian Critical Care Society; European Society of Clinical Microbiology and Infectious Diseases, et al: Surviving Sepsis Campaign: international guidelines for manage...
Ngày tải lên: 13/08/2014, 20:21
... flavin position is also marginally altered by the substitution of Y2 38 (Table 2). Steady-state and rapid reaction kinetics with D -alanine The ability of the Y2 38 mutants to catalyse D -alanine/ oxygen ... mutagenesis experiments, but only by replacing a phenylalanine (a nondisruptive mutation). In the case of RgDAAO we also changed the spatial arrangement in the active site b...
Ngày tải lên: 17/03/2014, 17:20
Báo cáo Y học: Role of histidine 42 in ascorbate peroxidase Kinetic analysis of the H42A and H42E variants pptx
... spectrometry The integrity of the variant proteins was examined to ensure that post-translational modification of the protein had not occurred. Analysis of H4 2A and H42E (data not shown) gave average masses ... 2522099, E-mail: emma.raven@le.ac.uk Abbreviations: APX, ascorbate peroxidase; pAPX, wild-type pea cytosolic APX; rAPX, recombinant wild-type pea cytosolic APX; H4 2A, a varia...
Ngày tải lên: 18/03/2014, 01:20
Báo cáo y học: "Role of Genetic Polymorphisms in Therapeutic Response to Anti-Asthma Therapy" pot
... significant potential clinical consequences. In a study by Martinez and colleagues, 269 children who were b2 naive, participating in a longitudinal asthma study, had their bronchodilator response measured ... loci may play a simultaneous role in response to pharmacother- apy. Future research regarding the mysteries of asthma will focus on not only phenotypic indicators but also...
Ngày tải lên: 08/08/2014, 21:20
Báo cáo y học: "Role of interleukin-7 in degenerative and inflammatory joint diseases" potx
... cartilage matrix synthesis and an inducer of cartilage degradation (by activation of MMPs), processes that lead to loss of cartilage integrity. TNFα also activates fibroblasts to produce catabolic factors ... (receptor activator of nuclear factor kappa B ligand) are crucial mediators in this IL- 7-driven osteoclast formation [7]. Interestingly, in the study of Long and colleague...
Ngày tải lên: 09/08/2014, 10:23
Báo cáo y học: "Role of STAT4 polymorphisms in systemic lupus erythematosus in a Japanese population: a case-control association study of the STAT1-STAT4 region" pot
... Tsukahara S, Kawaguchi Y, Terai C, Hara M, Tomatsu T, Yamanaka H, Horiuchi T, Tao K, Yas- utomo K, Hamada D, Yasui N, Inoue H, Itakura M, Okamoto H, Kamatani N, Momohara S: Association of STAT4 ... USA), and association was examined in 308 SLE patients and 306 healthy individuals. Statistical analysis Association of each SNP was analyzed by chi-square test. Because of the replicativ...
Ngày tải lên: 09/08/2014, 13:22
Báo cáo y học: " Role of clinical bioinformatics in the development network-based Biomarkers" docx
... biomarker as a new type of biomarkers with protein–protein interactions was initiated and investigated with the integration of knowledge on protein annotations, interaction, and signaling pathway. ... with clinical informatics, including patient complaints, history, therapies, clinical symptoms and signs, physician’s examinations, biochemical analyses, imaging profiles, pathologies...
Ngày tải lên: 10/08/2014, 09:22
Báo cáo y học: "Role of IL-33 in inflammation and disease" docx
... the ability of soluble ST2 to inhibit IL-33. Cytokine 2008, 42:358-364. 7. Hayakawa H, Hayakawa M, Kume A, Tominaga S: Soluble ST2 blocks interleukin-33 signaling in allergic airway inflammation. ... Schematic representation of the potential pro-inflammatory role of IL-33 in normal skin and in skin inflammation (atopic dermatitis and psoriasis). Damage to the skin such as by scra...
Ngày tải lên: 11/08/2014, 03:20
Báo cáo y học: "Role of carotid ultrasonography in the evaluation of cardiovascular risk in patients with rheumatoid arthritis" pptx
... Gonzalez-Gay MA, Gonzalez-Juanatey C, Piñeiro A, Garcia-Porrua C, Testa A, Llorca J: High-grade C-reactive protein elevation correlates with accelerated atherogenesis in patients with rheumatoid ... activation and rapid progression of intima media thickness. Arthritis Res Ther 2010, 12:R158. 2. Gonzalez-Juanatey C, Llorca J, Testa A, Revuelta J, Garcia-Porrua C, Gonzalez- Gay MA: In...
Ngày tải lên: 12/08/2014, 15:22