Báo cáo y học: "Inhibition of monocyte chemoattractant protein-1 prevents diaphragmatic inflammation and maintains contractile function during endotoxemi" pot
Báo cáo y học: "Inhibition of monocyte chemoattractant protein-1 prevents diaphragmatic inflammation and maintains contractile function during endotoxemi" pot
... 14:R187 http://ccforum.com/content/14/5/R187 Page 8 of 11 RESEARC H Open Access Inhibition of monocyte chemoattractant protein-1 prevents diaphragmatic inflammation and maintains contractile function during endotoxemia Katherine ... organ dysfunc- tion and mortality [17]. MCP-1 is primarily a chemoat- tractant for monocytes, memory T lymphocytes, and natural kill...
Ngày tải lên: 13/08/2014, 21:21
Báo cáo y học: "Characterization of monocyte/macrophage subsets in the skin and peripheral blood derived from patients with systemic sclerosis" pps
... healthy controls and SSc patients by immunohis- tochemistry. In addition, we evaluated the population of CD163 + or CD204 + cells in circulating monocytes of SSc patients by flow cytometric analysis. ... involvement of macrophage lineage in the pathogenesis of systemic sclerosis (SSc). To analyze the assembly of the monocyte/ macrophage population, we evaluated the expression...
Ngày tải lên: 12/08/2014, 14:22
Báo cáo y học: "Inhibition of TNFalpha in vivo prevents hyperoxia-mediated activation of caspase 3 in type II cells" pdf
... blot) and activity of caspases 8, 3, and 9 (colorimetrically). NF-kappaB activation was determined by EMSA, by increase of the p65 subunit in the nuclear fraction, and by immunocytochemistry using ... specificity of the bands. Hyperoxia increases the expression of TNFRI, TNFα and caspase 3 in vivoFigure 1 Hyperoxia increases the expression of TNFRI, TNFα and caspase 3 in v...
Ngày tải lên: 12/08/2014, 18:21
Báo cáo y học: " Inhibition of HIV-1 gene expression by Ciclopirox and Deferiprone, drugs that prevent hypusination of eukaryotic initiation factor 5A" potx
... modification of a lysine residue catalyzed by deoxyhypusine synthase and deoxyhypusine hydroxylase (DOHH). DOHH activity is inhibited by two clinically used drugs, the topical fungicide ciclopirox and ... catalyzed by DHS, of an aminobutyl moiety (blue) from spermidine onto the side chain of eIF5A lysine-50, yielding deoxyhypusine (Dhp); and its subsequent hydroxylation, catalyze...
Ngày tải lên: 12/08/2014, 23:22
Báo cáo y học: "Danaparoid sodium attenuates the increase in inflammatory cytokines and preserves organ function in endotoxemic rats" pot
... be other functions that may contribute to the attenuation of organ dysfunction. TNF-α and IL-1 are proinflammatory cytokines that are elabo- rated by monocytes or macrophages and play pivotal ... Iba 1 and Taku Miyasho 2 1 Department of Emergency and Disaster Medicine, Juntendo University, Tokyo, Japan, 2-1-1 Hongo, Bunkyo-ku, Tokyo 113-8421, Japan 2 Department of Veterinary Bi...
Ngày tải lên: 13/08/2014, 11:22
Tài liệu Báo cáo Y học: Inhibition of the MEK/ERK signaling pathway by the novel antimetastatic agent NAMI-A down regulates c-myc gene expression and endothelial cell proliferation ppt
... ERK1/2 activation and activity and totally counteracted phorbol ester-primed c-myc gene expression heavily suggests that the inhibitory effect of NAMI-A on c-myc gene expression may have occurred by suppressing ... cell proliferation of human mammary myoepithelial-like cells by hepatocyte growth factor/scatter factor depends on heparan sulfate proteoglycans and sustained phosphoryla...
Ngày tải lên: 21/02/2014, 01:21
Tài liệu Báo cáo Y học: Inhibition of nuclear pre-mRNA splicing by antibiotics in vitro pot
... inhibitory effect of erythromycin and Cl-tetracycline were not allevi- ated by Mg 2+ (Fig. 3). Kinetic analyses using increasing concentrations of erythromycin, Cl-tetracycline and streptomycin up ... ger splicing inhibition by Cl-tetracycline may be explained by the a dditional s ize and hydrophobicity introduced by the substitution, as is often the case in ribozyme inhibition by t...
Ngày tải lên: 21/02/2014, 15:20
Báo cáo Y học: Inhibition of hyaluronan synthesis in Streptococcus equi FM100 by 4-methylumbelliferone doc
... method of Laemmli [32]. Assay of cell-free HA synthesis Cell-free HA synthesis was performed by a modification of the method reported by Nakamura et al. [18]. Analysis of the transfer of UDP-[U- 14 C] ... level of the has operon containing the hyaluronan synthase gene or the protein level of hyaluronan synthase. Solubilization of the enzyme from membranes of MU-treated cells...
Ngày tải lên: 08/03/2014, 09:20
Báo cáo Y học: Inhibition of the SERCA Ca21 pumps by curcumin Curcumin putatively stabilizes the interaction between the nucleotide-binding and phosphorylation domains in the absence of ATP pot
... inhibition of platelet aggregation [6,7] and inhibition of inflammatory cytokine production in macrophages [8]. Curcumin has also been shown to affect the activity of a number of key enzymes such as cyclooxygenase ... sulfate, and 0.2 M sodium acetate. Two- hundred and fifty microliters of 5% (w/v) ammonium molybdate was then added and mixed thoroughly and 0.25 mL of ELAN...
Ngày tải lên: 08/03/2014, 23:20
Báo cáo Y học: Inhibition of glycosyl-phosphatidylinositol biosynthesis in Plasmodium falciparum by C-2 substituted mannose analogues pot
... in macrophages by glycosylphosphatidylinositols of Plasmodium, Trypanosoma, and Leishmania: activation of protein tyrosine kinases and protein kinase C by inositolglycan and diacylglycerol moieties. ... R.T. (1994) Glycosylphosphatidylinositols synthesized by asexual erythrocytic stages of the malarial parasite, Plasmodium falciparum. Candidates for plasmodial glycosylphosphatidyl...
Ngày tải lên: 31/03/2014, 23:20