Báo cáo y học: "GAS6 in systemic inflammatory diseases: with and without infection" docx

... including severe sepsis, sepsis, systemic in ammatory response syn drome without infection, and verifi ed infection – blood donors, systemic in ammatory res ponse syndrome patients with infections, ... research, including genetic screenings of the components of this system. © 2010 BioMed Central Ltd GAS6 in systemic in ammatory diseases: with and without infection...

Ngày tải lên: 13/08/2014, 21:21

... miR-124a binding in the 3’ UTR of cyclin- dependent kinase 2 (CDK2) and monocyte chemo- attractant protein 1 (MCP-1) mRNA. In fact, induction of miR-124a in RA synoviocytes signifi cantly suppressed ... syndrome SS is an autoimmune in ammatory exocrinopathy aff ect- ing the lacrimal and salivary glands, leading to dry eyes and mouth [64]. It is often associated with positive ant...

Ngày tải lên: 12/08/2014, 17:21

... Further RCTs on early SSc are needed to assess the real efficacy of CYC in inducing remission and increasing survival. In a previous issue of Arthritis Research & Therapy, Nannini and colleagues ... assess the efficacy of a drug is an RCT and therefore the only way to lift the curtain on the role of CYC in ILD will derive from a trial on patients with properly defined early...

Ngày tải lên: 09/08/2014, 01:22

... represent potential targets for cytokine action and hence manipulation, and many different cytokines may be involved. Second, although many cytokines may be involved in the pathogenesis of SLE, research ... meeting showed the breadth of interest in the role played by different cytokines in SLE. A large amount of work in mice, and a smaller body of evidence on the effects of anti...

Ngày tải lên: 09/08/2014, 01:22

... of cytokines. Furthermore, depending on the stage of inflammation or the biological effect under scrutiny, the same cytokine may have proinflammatory or anti- inflammatory activities. Many different ... the main problem is in fact the inhibition of repair activity. Any type of chronic joint inflammation, whether infectious, inflammatory, or autoimmune, will result in joint destruction...

Ngày tải lên: 09/08/2014, 14:22

... by the serine protease thrombin to be functional [173]. A functional serine- valine-valine-tyrosine-glutamate-leucine-arginine (SVVYGLR) domain has a cryptic structure in intact osteopontin and ... TNF-a contributing to control its pro -inflammatory activity in the tissue. The cytokine IL-18 plays a role in inflammatory states like sepsis, arthritis and inflammatory bowel disea...

Ngày tải lên: 11/08/2014, 06:22

... the prototypic example of a transcriptional activator in the setting of inflammation, being activated in response to multiple inflammatory mediators including pro -inflammatory cytokines and bacterial endotoxin. ... in vascular inflammation and aging Transcription Factors Pro-/Anti -inflammatory Selected Target Genes Alterations with Aging NF-κB Pro -inflammatory MCP-1, ICAM-...

Ngày tải lên: 11/08/2014, 08:22

... for managing weight gain associated with atypical antipsychotics. Psychiatr Serv 2003, 54:1155-1157. 19. Menza M, Vreeland B, Minsky S, Gara M, Radler DR, Sakowitz M: Managing atypical antipsychotic-associated ... Centorrino F, Wurtman JJ, Duca KA, Fellman VH, Fogarty KV, Berry JM, Guay DM, Romeling M, Kidwell J, Cincotta SL, Baldessarini RJ: Weight loss in overweight patients maintained...

Ngày tải lên: 11/08/2014, 16:23

... report early satiety and loss of appetite. This woman had a history of peptic ulcer disease over 20 years ago in Kenya. It had led to GOO requiring truncal vagotomy and gastrojejunostomy. In order to investigate the ... of sticky concretions, which pass into the duodenum and jejunum unfragmented. More evidence has since emerged supporting this theory. Another study [12] involving 11...

Ngày tải lên: 11/08/2014, 21:22

... that originally promote angiogenesis include members of the CXC chemokine family, characteristically heparin binding proteins which on structural level have four highly conserved cysteine amino acid ... described in retinal pigmented epithelial cells during diabetic retinopathy and then in young proliferating fibroblasts [20]. Its expression in retinal cell lines has been documented t...

Ngày tải lên: 12/08/2014, 16:20