Báo cáo y học: "Host adaptive immunity deficiency in severe pandemic influenza" ppt

... Jurkovich GJ and Roy-Byrne P Predicting posttraumatic distress in hospi- talized trauma survivors with acute injuries Am J Psychiatry 2002, 159:941-946 14. King DW, King LA, Foy DW, Keane TM and Fairbank ... Psychiatry 1995, 152:1705-1713 9. Harvey PD and Yehuda R Strategies to study risk for the devel- opment of PTSD In: Risk factors for posttraumatic stress disorder (Ed- it...

Ngày tải lên: 08/08/2014, 20:23

... CD4- peridinin chlorophyll protein mAbs and CD28-phycoerythrin mAbs and were permeabilized with 0.05% Tween 20 to stain intracellularly with fluorescein isothiocyanate-conjugated anti- perforin mAbs ... online http://arthritis-research.com/content/7/6/R1412 R1412 Vol 7 No 6 Research article Between adaptive and innate immunity: TLR4-mediated perforin production by CD28 n...

Ngày tải lên: 09/08/2014, 07:20

... affect chondrocytes pro- foundly, and chondrocytes might possibly try to compensate for the CIX deficiency by the overexpression of cartilage components. To test our hypothesis about whether cartilage ... instability and changed exposure of Figure 4 Improved binding of anti -collagen type II antibodies to cartilage defi-cient in collagen type IXImproved binding of a...

Ngày tải lên: 09/08/2014, 08:22

... regulating body weight. Leptin deficiency results in severe obesity and a variety of endocrine abnormalities in animals and humans. Several studies indicated that leptin plays an important role in immune ... potential role of leptin in RA. Role of leptin in other immune- mediated inflammatory conditions Several studies suggest a potential implication of...

Ngày tải lên: 09/08/2014, 08:22

... Previously, Garred and coworkers [23] showed that MBL2 exon 1 variant allele carrier status was associated with early age at onset of RA, which is the adult counterpart of polyarthritis [26]. Garred and ... and low expression of MBL. The influence of the X /Y allele was also determined by studying six 'extended' genotype groups: YA/YA, YA/XA, XA/XA, YA/O, XA/O and...

Ngày tải lên: 09/08/2014, 10:23

... properly cited. Abstract Introduction Infections commonly complicate the course of systemic lupus erythematosus (SLE). Our aim is to investigate the clinical predictors of major infections in patients ... Working Party on Systemic Lupus Erythematosus: Morbidity and mortality in systemic lupus erythematosus during a 10- year period. A comparison of early and late ma...

Ngày tải lên: 09/08/2014, 14:22

... including the cynomolgus macaque [5]. In these primates, active and latent disease seem to be overlapping entities rather than clearly distinct syndromes. e ability to measure Mtb burden in ... 7:845-855. 5. Lin PL, Pawar S, Myers A, Pegu A, Fuhrman C, Reinhart TA, Capuano SV, Klein E, Flynn JL: Early events in Mycobacterium tuberculosis infection in cynomolgus macaques. I...

Ngày tải lên: 09/08/2014, 22:23

... case of sinus of valsava aneurysm in Blau syn- drome. In isolated unruptured aneurysms of a sinus of Valsalva without compromise of the aortic valve and/or the coronary ostia, repair may be accomplished ... first case of sinus of valsava aneurysm in Blau syndrome. We believe t hat this is some form autoimmune a ortitis, but further evidence is needed. Sinus of Val...

Ngày tải lên: 10/08/2014, 10:20

... this article as: Chakrabarti et al.: Host gene expression profiling in influenza A virus-infected lung epithelial (A5 49) cells: a comparative analysis between highly pathogenic and modified H5N1 ... was done using gene annotation files and raw data were extracted into MS EXCEL. Data Analysis Data was analyzed using GENOWIZ Microarray and Pathway...

Ngày tải lên: 12/08/2014, 01:21

... has poor sensitivity and specifi city and high variability in critically ill patients [2]. In addition, the immunoassays used to determine total cortisol are subject to inter- ference, with ... examine tissue cortisol levels. Although measuring tissue cortisol may be more pathophysiologically relevant than measuring plasma levels, it is not clear how measuring cortisol l...

Ngày tải lên: 13/08/2014, 20:21

... impaired development of adaptive immunity in the most severe cases of pandemic influenza, leading to an unremitting cycle of viral replication and innate cytokine-chemokine release. Interruption of this ... the increased incidence of ba cterial superinfection observed in severe disease following infection by p2009A(H1N1) [2]. Conclusions Our findings suggest a state of host ada...

Ngày tải lên: 13/08/2014, 21:21

... controls Reassuringly, closer inspection of several of the predicted cases of lost genes pointed to recently published findings of lineage-specific biology. Hedgehog signaling pathway rearrangements in Drosophila Hedgehog ... ancestors, including the inferred number of losses (Figure 1), and the assumed split of insects and vertebrates about 600 MYA against the species...

Ngày tải lên: 14/08/2014, 08:20

... of chromatin-modifying protein complexes in transcriptional regulation, and four captured our interest especially. They all concern work on a ribonucleo- protein complex that has a defined biological ... JIL1 protein kinase. According to the prevalent model, the DCC is necessary for upregulating gene expression from the single male X chromo- some precisely twofold, thus ensuring that ma...

Ngày tải lên: 14/08/2014, 14:21

... question using the yeast two-hybrid protein- protein interaction system. Building resources The yeast two-hybrid system allows the identification of potential binary protein-protein interactions by exploiting the ... primary disease pro- teins, and used yeast two-hybrid technology to place them into a protein-protein interaction network. They identified 770 protein-protein interac...

Ngày tải lên: 14/08/2014, 17:22

... networks. In this study, we report a method employing the Shokat strat- egy to identify direct cyclin A -CDK2 substrates in human cell lysates. CDK2 is activated by both the cyclin E and cyclin A subunits, ... 6Autophosphorylation of cyclin A -CDK2 in vitroAutophosphorylation of cyclin A -CDK2 in vitro.Click here for fileAdditional data file 7Cyclin B -CDK2 (F80A) and...

Ngày tải lên: 14/08/2014, 21:20