Báo cáo y học: "Withholding selective decontamination of the digestive tract from critically ill patients must now surely be ethically questionable given the vast evidence base" pdf

... Withholding selective decontamination of the digestive tract from critically ill patients must now surely be ethically questionable given the vast evidence base. Critical Care 2010 14:443. Submit your ... Brazzi L, Parmelli E: Antibiotic prophylaxis to reduce respiratory tract infections and mortality in adults receiving intensive care. Cochrane Datab...

Ngày tải lên: 13/08/2014, 21:21

... provide evidence, for the first time, of the presence of MPs in sputa obtained from CF patients. The membrane composition of MPs reflects the plasma membrane of the original cell at the precise ... a study for the identification and charac- terization of MPs in the sputa of CF patients. Patients and Methods Study patients The study was approved by, and p...

Ngày tải lên: 12/08/2014, 11:22

... clearance between CVVH and CVVHD to increase. Secondly, we used only polyacrylonitrile filters because they are one of the most commonly used biosynthetic membranes worldwide: our results can not be ... clinically significant therapy down- time and increase discrepancy between prescription and effective delivery [8]. A recent single center study showed that mean filter life in critical...

Ngày tải lên: 12/08/2014, 23:23

... both the mortality and the morbidity in critically ill patients in the surgical intensive care unit [3]. In another study of medical critically ill patients, mor- bidity but not mortality was ... level below 6 mmol/l had a detrimental outcome. The mechanisms of the effects of insulin in the critically ill are not completely understood. The purpose of the...

Ngày tải lên: 13/08/2014, 20:21

... cytokines are key mediators of the in ammatory response to sepsis. Leptin, a hormone mainly generated by adipocytes, acts centrally in the hypothalamus to regulate body weight and energy ... leptin in critically ill patients is important for early diagnosis and di erentiation between sepsis and non-infectious systemic in ammatory response syndrome (SIRS). The early diagn...

Ngày tải lên: 13/08/2014, 20:21

... mortality in medical ICU patients [2]. Of note, the power analysis for this trial was based on the number of patients requiring ≥3 days of stay in the ICU. Since the trial recruited only 767 patients ... to the upper limit of SGC than the other negative trials, the study protocol allowed for early termination because of safety.  e increase in the inciden...

Ngày tải lên: 13/08/2014, 20:21

... polymyxin B, tobramycin and amphotericin B), and decontamination of the rest of the digestive tract by local administration (through a nasogastric tube) of the aforementioned antibiotics. Another ... against tobramycin, ceftazidime, imipenem and ciprofloxacin. The hopes are that this study will at long last end the debate about the efficacy and safety of SDD in crit...

Ngày tải lên: 12/08/2014, 19:22

... ICU mortality and hospital mortality for patients receiving SDD has recently been presented [2]. SDD consisted of nonabsorbable antibiotics in the oral cavity and the rest of the digestive tract, systemic ... that, from now on, patient survival in the ICU and preferably in hospital should be the primary endpoint of such studies. Also, the design of the study d...

Ngày tải lên: 12/08/2014, 19:22

... care + SDD, selective decontamination of the digestive tract; SOD, selective oropharyngeal decontamination. + applied four times a day. † Oral paste consists of polymyxin, tobramycin, amphotericin ... as selective decontamination of the di gestive tract (SDD) [3,4] and selective oropharyngeal deconta- mination (SOD) [5-7]. The concept of SDD consists of the...

Ngày tải lên: 13/08/2014, 21:21

... affinity of glycopeptides to the antibody [18]. Conventional pepscan analysis however, does not allow easy analysis of the contribution of the carbohydrate portion. To assess the involvement of carbohydrates ... complex with SM3 The amino acids of the glycopeptide give STD signals of about equal intensity from Asp2 to Pro5 with only Pro1 and the methyl group of t...

Ngày tải lên: 21/02/2014, 15:20