Báo cáo y học: " APCAP - activated protein C in acute pancreatitis: a double-blind randomized human pilot trial" ppsx

... Siriwardena AK: Drotrecogin alfa (recombinant human activated protein C) in severe acute pancreatitis. Crit Care 2005, 9:32 1-3 22. 17. Bradley EL: A clinically based classification system for acute ... 25:358-e 9-3 5 8- e15. doi:10.1186/cc9203 Cite this article as: Pettilä et al.: APCAP - activated protein C in acute pancreatitis: a double-blind r...

Ngày tải lên: 13/08/2014, 21:21

... Medicine and Anesthesia, University of California, San Francisco, San Francisco, CA 9414 3-0 624, USA Corresponding author: Michael A Matthay, michael.matthay@ucsf.edu Published: 21 May 2009 Critical ... Medicine and Anesthesia, University of California, San Francisco, San Francisco, CA 9414 3-0 624, USA 2 Cardiovascular Research Institute and the Division of Pulmonary and Critical Care...

Ngày tải lên: 13/08/2014, 16:20

... ventilation. Abbreviations APC, activated protein C; ERK, extracellular-regulated kinase; LPS, lipopolysaccharide; VILI, ventilator-induced lung injury. Competing interests The author declares that he has no competing ... Endotoxemia and sepsis mortality reduction by non-anticoagulant activated protein C. J Exp Med 2007, 204:243 9-2 448. 6. Bae JS, Yang L, Rezaie AR: Receptors...

Ngày tải lên: 13/08/2014, 20:21

... Schwarz HP, Smith OP: Activated protein C inhibits lipopolysaccharide-induced nuclear translo- cation of nuclear factor kappaB (NF-kappaB) and tumour necrosis factor alpha (TNF-alpha) production ... been identified as participating in the anticoagulant activity but not in cellular effects. Hence, variants have been designed with greater anti-apoptotic activity and reduced anticoagul...

Ngày tải lên: 13/08/2014, 03:20

... drug-induced acute pancreatitis. A large, UK- based cohort study found no increased risk of acute pan- creatitis following acid-suppressing drug administration [7]. Most cases of acute pancreatitis are ... mmol/litre). At day 8 she became unwell with epigastric pain and vomiting. An abdominal X-ray excluded bowel perforation and clinical chemistry revealed normal liver function tests...

Ngày tải lên: 11/08/2014, 19:21

... acetylcholine (ACh) from choline and acetyl coenzyme A is catalyzed by the enzyme choline acetyltransferase (ChAT, acetyl-CoA:cho- line O-acetylotransfe rase, EC 2.3.1.6) [1]. Following syn- thesis, ACh ... mitogen -activated protein kinase kinase; NGF, nerve growth factor; PKA, cyclic AMP -activated protein kin- ase; STAT, signal transducer and activator of transcription; VAChT, vesi...

Ngày tải lên: 31/03/2014, 21:21

... Gabain A, Baccarini M: Salmonella typh- imurium and lipopolysaccharide stimulate extracellularly regulated kinase activation in macrophages by a mechanism involving phosphatidylinositol 3-kinase ... (nmoles/ml) Herbimycin A inhibits BCG- and SP -A- BCG killing by rat bone marrow macrophagesFigure 2 Herbimycin A inhibits BCG- and SP -A- BCG killing by rat bone marrow macrophages. RBM...

Ngày tải lên: 12/08/2014, 14:20

... Sepsis; rhAPC = recombinant activated protein C; SSC = Surviving Sepsis Campaign. Available online http://ccforum.com/content/10/1/114 Abstract The PROWESS (Recombinant Human Activated Protein C Worldwide ... Evalu- ation; ARDS = acute respiratory distress syndrome; ENHANCE = Extended Evaluation of Recombinant Human Activated Protein C; PROWESS = Recombinant Human Act...

Ngày tải lên: 12/08/2014, 23:21

... which may be challenged under article 3 of the ECHR. Delays on dis- charging a patient because of failure to set-up aftercare services may breach article 5(4). Difficulty of access to information ... allow patients' data to count in audit, research, and financial planning; thus facilitating their inclusion in user and information groups, and strategies aimed at improving standards...

Ngày tải lên: 08/08/2014, 21:20

... addition, phacocytic cells are able to directly cleave C5 and locally generate C5 a [19]. Maj and colleagues revealed that peripheral mononuclear cells (PBMCs) isolated from anorexia ner- vosa ... ner- vosa patients exhibited significantly elevated levels of activated intracellular G proteins, indicating increased PBMC activity in these patients [20]. Thus, activated PBMCs and neutr...

Ngày tải lên: 09/08/2014, 01:21