Báo cáo y học: "Understanding immune dysfunctions in sepsis patients" docx

... serine/threonine protein kinase (AKT) were determined by real-time quantitative PCR. (a) In the case of TNFα, induction levels were also analysed when monocytes were challenged with lipopolysaccharide ... Monitoring immune dysfunctions in the septic patient: a new skin for the old ceremony. Mol Med 2008, 14:64-78. 6. Levy M, Fink MP, Marshall JC, Abraham E, Angus D, Cook D, Cohen J...

Ngày tải lên: 13/08/2014, 21:21

... the increase in monocyte apoptosis, and the lower release of pro-inflammatory cytokines, namely tumor necrosis factor-alpha and interleukin-6, from monocytes after stimula- tion with lipopolysaccharide ... stimulation by endotoxin [4]. Endotoxin tolerance has been considered a paradigm of immunoparalysis [5], which is present not only in sepsis but also in systemic inflammatory respon...

Ngày tải lên: 13/08/2014, 20:21

... mainly regulated by proinflammatory cytokines [37]. Proin- flammatory cytokines were significantly decreased in early septic shock and did not differ in late septic shock. Addition- Figure 3 Interleukin ... proinflammatory cytokines were signif- icantly lower in chronic alcoholic patients than in nonalcoholic patients in early sepsis is an important new finding. The proin- flammat...

Ngày tải lên: 12/08/2014, 20:20

... 20). Twelve patients undergoing laparoscopic cholecystectomy and 20 healthy subjects were served as control groups. Intracellular cytokine staining in CD4+ T lymphocytes was identified to characterize ... monitoring patients post-surgery. Competing interests The authors declare that they have no competing interests. Authors' contributions MI was involved in the design of the study an...

Ngày tải lên: 09/08/2014, 04:21

... even in the majority of patients in a given diagnostic category. Introduction Autoimmune myositis (AIM) is a syndrome characterized by involvement of the cellular and humoral immune systems in skeletal ... history, physical findings, and laboratory investiga- tions were obtained by retrospective medical record review using a standardized protocol. Written consent was obtained from tre...

Ngày tải lên: 09/08/2014, 10:20

... DeWoody K, Williamson P, Braun J, Ankylosing Spondylitis Study for the Evaluation of Recombinant Infliximab Therapy Study Group: Efficacy and safety of infliximab in patients with ankylosing spondylitis: ... Garrett S, Jenkinson T, Kennedy LG, Whitelock H, Gaisford P, Calin A: A new approach to defining disease status in ankylosing spondylitis: the Bath Ankylosing Spondylitis Disease Acti...

Ngày tải lên: 12/08/2014, 12:20

... rapid decline in lung function, particularly in the early stages of COPD, would require a study of reproducibility of FEV 1 and its decl ine in individual patients, possibly at short intervals ... of decline in the SGRQ total score increased linearly wi th each quarti le increase in the post-bronchodilator decline in FEV 1 (Figure 3). The range was from an improvement over time i...

Ngày tải lên: 12/08/2014, 14:20

... LOC388720are involved in the KEGG (Kyoto Encyclopaedia of Genes and Genomes) ribosome pathway. RPS6 is also involved in the insulin signalling and the mTOR signalling pathway. MCM3 and VIM are involved in ... obstructive pulmonary disease (COPD) is a respiratory inflammatory condition with autoimmune features including IgG autoantibodies. In this study we analyze the complexity of the...

Ngày tải lên: 12/08/2014, 14:20

... ml/kg hypertonic saline in hydroxyethyl starch. Following administration there was a small effect on oxygenation by increasing cardiac output and oxygen delivery. There was no control group in this study for ... with sepsis are only descriptive. Furthermore, administration of hypertonic saline solutions during the early stages of septic shock when the patient is not yet hyperdynamic has...

Ngày tải lên: 12/08/2014, 19:21

... prophylaxis in trauma patients may be the lack of intra-institutional data concerning the inci- dence of clinically important bleeding. Only 27% of the institu- tions surveyed evaluated the incidence ... severe injury as defined by an Injury Severity Score greater than 16 and single-system injuries (e.g. head and spinal cord injuries) of the central nervous system [5]. However, the use of r...

Ngày tải lên: 12/08/2014, 19:21