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Báo cáo y học: "Time course of nitric oxide synthases, nitrosative stress, and poly(ADP ribosylation) in an ovine sepsis model" pot

Báo cáo sinh học:

Báo cáo sinh học: "Time-course of sFlt-1 and VEGF-A release in neutropenic patients with sepsis and septic shock: a prospective study" pptx

... observation of higher sFlt-1 and VEGF -A levels in non -neutropenic patients with sepsis at “early” timepoints. Again, we believe that rather than a difference in the kinetics of sFlt-1 and VEGF -A release ... thetime of fever onset was not assessed.Figure 3 sFlt-1 and VEGF -A levels in patients with FN .Combined analysis sFlt-1 and VEGF -A levels in patients with FN. Actual sFlt-1 and VEGF -A serum ... in sFlt- 1and/ or VEGF -A levels of patients with a worseprognosis and accurately discriminate FN patients with different outcomes.The major sources of VEGF -A in sepsis are still a matter of debate, and...
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báo cáo hóa học:

báo cáo hóa học:" Time-course of sFlt-1 and VEGF-A release in neutropenic patients with sepsis and septic shock: a prospective study" pdf

... RESEARCH Open Access Time-course of sFlt-1 and VEGF -A release in neutropenic patients with sepsis and septic shock: a prospective studyBrunna E Alves1, Silmara AL Montalvao1, Francisco JP Aranha1, ... VEGF -A levels increased in liver, kidney and heart, and no difference could be detected between VEGF -A levels in serum and plasma, arguing against a majorroleofplateletsasasourceofVEGF -A[ 8] .In our ... in non -neutropenic patients with sepsis at “early” timepoints. Again, we believe that rather than a difference in the kinetics of sFlt-1 and VEGF -A release in patients with neutro penia, this...
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Báo cáo y học:

Báo cáo y học: "The abilities of improved schizophrenia patients to work and live independently in the community: a 10-year long-term outcome study from Mumbai, India" ppsx

... research The abilities of improved schizophrenia patients to work and live independently in the community: a 10-year long-term outcome study from Mumbai, IndiaAmresh Kumar Srivastava*1,5, Larry ... Meghana Thakar1, Nilesh Shah3 and Gurusamy Chinnasamy4Address: 1Mental Health Foundation of India (PRERANA Charitable Trust) and Silver Mind Hospital, Mumbai, Maharashtra, India, 2Department ... few advance-ments in pharmacotherapy or psychosocial management, and 'institutionalisation' was the sad reality in mentalhealth. Parallel to physical health, changing expectationsin...
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Báo cáo y học:

Báo cáo y học: "The course of untreated anxiety and depression, and determinants of poor one-year outcome: a one-year cohort study" ppt

... the PNCQ has not specificallybeen validated, a study comparing PNCQ data from anAustralian and a Dutch sample of primary care patientswith anxiety and/ or depression, showed many similari-ties ... youngestparticipant being 18 years of age and the oldest 65.Participants had an average of 12.0 years (sd. 3.4 years) of education, ranging from 5 to 18 years. The majority of patients had a six-month ... one-year course of anxiety and depression in untreated and treated patients sepa-rately by performing multilevel repeated measuresANCOVA’s, using baseline and one-year follow-up scalescores of symp...
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Báo cáo y học:

Báo cáo y học: " Central role of nitric oxide in the pathogenesis of rheumatoid arthritis and systemic lupus erythematosus" potx

... NG-mono-methyl-L-arginine and nitronidazole both inhibited its production, suggesting a role for NO in regulating IFN-γ synthesis [17]. NO preferentially promotes IFN-γ syn the- sis and type  ... evidence for increased endogenous NO synthesis, suggest ing that overproduction of NO may be important in the pathogenesis of RA.  e in amed joint in RA is the predominant source of NO [45,46]. ... it is relatively easy to obtain large numbers of these cells. Tregs seem to have Table 1. Nitric oxide- induced T cell functions in sysemic lupus erythematosus and rheumatoid arthritis Altered...
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Báo cáo y học:

Báo cáo y học: " Differential effects of cigarette smoke on oxidative stress and proinflammatory cytokine release in primary human airway epithelial cells and in a variety of transformed alveolar epithelial cells" potx

... release in primary human airway epithelial cells and in a variety of transformed alveolar epithelial cells Aruna Kode, Se-Ran Yang and Irfan Rahman*Address: Department of Environmental Medicine, ... CentralPage 1 of 3(page number not for citation purposes)Respiratory ResearchOpen AccessCorrection Differential effects of cigarette smoke on oxidative stress and proinflammatory cytokine release ... 2 in this paper) &apos ;Cigarette smoke extract caused necrosis with no or little evidence of apoptosis in primary human small airway epithelial cells (SAEC)' of our published article [1],...
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Báo cáo y học:

Báo cáo y học: "Time course of airway remodelling after an acute chlorine gas exposure in mice" pdf

... airway remodelling after an acute chlorine gas exposure in miceStephanie A Tuck1, David Ramos-Barbón2, Holly Campbell1, Toby McGovern1, Harry Karmouty-Quintana1 and James G Martin*1Address: ... reported an increase, albeit transient, in ASM quantity in rats after acute exposure to Cl2 gas. The signals involved in repair and in the repopulation of the epithelium after Cl2-induced injury ... Corresponding author AbstractAccidental chlorine (Cl2) gas inhalation is a common cause of acute airway injury. However, littleis known about the kinetics of airway injury and repair after Cl2 exposure. ...
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Báo cáo y học:

Báo cáo y học: " Differential effects of cigarette smoke on oxidative stress and proinflammatory cytokine release in primary human airway epithelial cells and in a variety of transformed alveolar epithelial cells" pps

... ResearchOpen AccessResearch Differential effects of cigarette smoke on oxidative stress and proinflammatory cytokine release in primary human airway epithelial cells and in a variety of transformed alveolar ... in primary human small air-way epithelial cellsFigure 1 Cigarette smoke extract differentially caused cytotoxicity in a variety of alveolar epithelial cells and in primary human small airway ... lines as well as in primary human small airway epithelial cells. However,CSE triggered NF-κB activation and pro-inflammatory cytokine release in primary human small airway epithelial cells but...
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Báo cáo y học:

Báo cáo y học: " Time course of plasma gelsolin concentrations during severe sepsis in critically ill surgical patients" pptx

... study does not unequivocally elucidate the role played byFigure 2 Time course of plasma gelsolin levelsTime course of plasma gelsolin levels. Presented are the courses over time of plasma gelsolin ... sepsis via its binding and neutral-izing inflammatory mediators during the course of sepsis. Toour knowledge, this is the first study to examine the time course of plasma gelsolin changes and ... protein that ispart of an 'actin-scavenging' system. Studies suggest that plasma gelsolin may play a crucial role in the pathophysiology of sepsis. Little is known about the course of plasma...
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Báo cáo y học:

Báo cáo y học: "Time course of angiopoietin-2 release during experimental human endotoxemia and sepsis" doc

... theassociation of Ang-2 with soluble adhesion molecules and inflammatory cytokines; and the early time course of Ang-2 release during sepsis in critically ill patients.Methods In 22 healthy volunteers during ... rapidly released from Weibel-Palade and has been identified as a non-redundant gatekeeper of endothelial activation. We aimed to study: the time course of Ang-2 release during human experimental endotoxemia; ... we wanted to study the time course of Ang-2 release, and the association of Ang-2 with solubleadhesion molecules and inflammatory cytokines in a graded and well-defined human endotoxemia model....
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Báo cáo y học:

Báo cáo y học: "Time course of nitric oxide synthases, nitrosative stress, and poly(ADP ribosylation) in an ovine sepsis model" pot

... distribution, and reproduction in any medium, provided the original work is properly cited.ResearchTime course of nitric oxide synthases, nitrosative stress, and poly(ADP ribosylation) in an ovine sepsis ... Health and the American Physio-logical Society for the care and use of laboratory animals.Animal modelThe ovine model of ALI and sepsis induced by smokeinhalation and instillation of Pseudomonas ... changes were associated with an early and transient increase in eNOS and an early and profound increase in iNOS expression, while expression of nNOS remained unchanged. Both 3-NT, a marker of...
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Báo cáo y học:

Báo cáo y học: "Toxicogenomic analysis of Caenorhabditis elegans reveals novel genes and pathways involved in the resistance to cadmium toxicity" potx

... 5).Protein interaction analysis reveals a novel pathway involved in the response to cadmium In order to further define the molecular mechanisms of the cadmium defense response, the program Cytoscape ... when the expression of only one of the redundant genes is affected.By integrating the RNAi assay results into the protein interac-tion network, a novel signal pathway involved in cadmium resistance ... functions may be disrupted by cad-mium toxicity.Discovery of novel genes and pathways involved in cadmium resistance In C. elegans, mtl-1, mtl-2, cdr-1 and ttm-1 (Toxin-regulatedtarget of p38...
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Báo cáo y học:

Báo cáo y học: "Molecular basis of telaprevir resistance due to V36 and T54 mutations in the NS3-4A protease of the hepatitis C virus" pdf

... in the ligand binding pocket, similar to the placement of the cyclo-propyl group of CPX in 1RTL. The cyclopropyl group is buried in the surface cavity and faces towards the aromatic ring of F43. ... displacement of the side chain of this residue, thereby changing the shape of the cavity. Thus, the V36 mutants affect only the shape of the cyclopropyl binding cavity, which is in agreement with the corresponding ... vol-ume of the cavity using the surface of the mutant structures,which covers the surface of the wild-type structure in the cyclopropyl binding pocket. In summary, the moleculardynamics simulations...
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Báo cáo y học:

Báo cáo y học: "Global analysis of alternative splicing regulation by insulin and wingless signaling in Drosophila cells" ppt

... in alternative splicing induced by activation of two distinct signaling pathways, insulin and wingless, in Drosophila cells in culture.Results: Alternative splicing changes induced by insulin ... 1Activation of insulin and wingless signaling pathways in Drosophila S2 cells. (a) Schematic representation of the insulin and wingless signal transduction cascades and controls of their activation in ... and wingless on alter-native splicing. Numerous changes in alternatively spliced mRNA isoforms induced by insulin and winglessFigure 2Numerous changes in alternatively spliced mRNA isoforms induced...
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