Báo cáo y học: Macrolides and community-acquired pneumonia: is quorum sensing the key" docx

... Ltd Macrolides and community-acquired pneumonia: is quorum sensing the key? Matt P Wise 1 *, David W Williams 2 , Michael AO Lewis 2 and Paul J Frost 1 COMMENTARY *Correspondence: mattwise@doctors.org.uk 1 Adult ... monotherapy in severe CAP, and this approach is recommended by a number of organisations [4,5].  e Infectious Diseases Society of America/American  orac...

Ngày tải lên: 13/08/2014, 21:20

... these syndromes is the inaccuracy of etiologic diagnosis for community-acquired pneumonia (CAP).  e CDC (Centers for Disease Control and Prevention) has recognized this diffi culty and conceded ... respiratory cultures). One of the lasting eff ects of the 2009 novel H1N1 infl uenza epidemic may be the increasing sophistication and availability of molecular diagnostic tests...

Ngày tải lên: 13/08/2014, 20:21

... shows the results of the strand-break assay of yeast tRNA Phe in the presence of Ami, Cu(II)-Ami and the Cu(II)-Ami-H 2 O 2 system, performed by means of poly- acrylamide gel electrophoresis. Strikingly, ... in the anticodon loop, at the hipermodified base Y3 7 (wybutine) (Figs 6 and 7). Also other amino- glycosides, as kanamycin A, neomycin B and a synthetic neomycin-neomyc...

Ngày tải lên: 21/02/2014, 01:21

... for the biosynthesis of glycosaminoglycan (GAG chains and, subsequently, for the production of aggrecan and other proteoglycans. CS is a major component of the extracel- lular matrix of many connective ... a member of the tumour necrosis factor superfamily, is an essen- tial cytokine for osteoclast differentiation and bone loss. On the other hand, OPG is considered a deco...

Ngày tải lên: 09/08/2014, 10:21

... dermatophyte genomes encode the basic meta- bolic machinery for glycolysis, tricarboxylic acid cycle, glyoxylate cycle, pentose phosphate shunt, and synthesis of all 20 standard a mino acids and the ... Organization and evolutionary trajectory of the mating type (MAT) locus in the dermatophyte and dimorphic fungal pathogens. Eukaryotic Cell 2010, 9:46-58. 39. Aimanianda V, Bay...

Ngày tải lên: 09/08/2014, 22:23

... priority, this includes preformulation ev aluation. The current study addressed this issue by characterizing the stability of RC-101 and thereby informing the formulation develop- ment and, improving ... peroxide. Methods Materials Retrocyclin-1 (RC-101) was synthesized by the Peptide Synthesis Facility at the University of Pittsburgh (Pitts- burgh, PA). As part of quality contro...

Ngày tải lên: 10/08/2014, 05:22

... heel rise (> 3.0 cm). This measure was then normalised by dividing it by the length of the shoe. This normalised measure takes into account all factors which will determine the position of the ... collection and analysis, and with DB collected all data. All authors were involved in the development of the scale and the interpretation of the results, helped draft the...

Ngày tải lên: 10/08/2014, 21:23

... activity. Copyright and intellectual property rights are put forward as reasons for not publishing details of their intervention protocols and manuals. This is an ethical and political issue for the ... subse- quently introduced and scaled up to provide population benefits. There is evidence that the more clearly the effec- tive core components of an intervention are known...

Ngày tải lên: 11/08/2014, 05:21

... gratification. These employees present a cynical attitude [17] and are invaded by guilty feelings due to the ambivalence they feel for their work and by their de sire for change. These people have lost their ... their involvement and les- sening of their dedication to work in the interest of satisfying their personal needs. On the other hand, the variables “occupation” and “ge...

Ngày tải lên: 11/08/2014, 15:22

... contributions FAA conceived the study and supervised collection of data. FAA and JUO designed the study and analyzed the data. FAA and JUO drafted the manuscript. All authors read and approved the manuscript. Competing ... calculated: the total score is the average of all 25 items; the anxiety score is the average of the 10 anxiety items; while the depressi...

Ngày tải lên: 11/08/2014, 16:22