Báo cáo y học: " Immune status in sepsis: the bug, the site of infection and the severity can make the difference" docx

... immunohistochemical localization of inflammatory cells in idiopathic inflammatory myopathies Reference Polymyositis Dermatomyositis Inclusion-body myositis T lymphocytes [9] 53 patients. T lymphocytes were least ... concerning the role of T lymphocytes, B lymphocytes, dendritic cells, and other antigen-presenting cells (APCs) in the pathophysiology of IIMs. T lymphocytes T...

Ngày tải lên: 09/08/2014, 10:20

... Access Health status in COPD cannot be measured by the St George’s Respiratory Questionnaire alone: an evaluation of the underlying concepts of this questionnaire Leonie Daudey 1,2* , Jeannette B ... for definitions of the sub- domains and corresponding instruments. Statistical Analyses The relationships between the sections of the SGRQ...

Ngày tải lên: 12/08/2014, 11:22

... et al.: Health status in the TORCH study of COPD: treatment efficacy and other determinants of change. Respiratory Research 2011 12:71. Submit your next manuscript to BioMed Central and take ... Respiratory Research 2011, 12:71 http://respiratory-research.com/content/12/1/71 Page 4 of 8 RESEARCH Open Access Health status in the TORCH study of CO...

Ngày tải lên: 12/08/2014, 13:22

... clearly been a paradigm shift in recent years from inhibiting pro-inflammatory cytokines to selectively augmenting the cytokine response within a specific com- partment in infected patients that have ... 300àg/day of G-CSF subcutaneously or placebo in addition to conven- tional antibiotic therapy. The duration of treatment was up to 10 days. Primary objectives were to determin...

Ngày tải lên: 12/08/2014, 18:20

... basic research. The potential key role of proteins that were originally believed to be exclusively involved in coagulation in the inflammatory response provides an exciting potential mechanism(s) ... augmenting or inhibiting the contribution of the clotting cascade components to inflammation would be required for determining the selection and dosing of potential new therapies. Alter...

Ngày tải lên: 12/08/2014, 19:21

... of inflammatory mediators on the brain. Investigations addressing SAD will remain difficult due to the problem of correctly identifying and quantifying this entity. The value of monitoring cerebral ... one could speculate that, in analogy to traumatic brain injury, severe brain dysfunction is necessary to disturb CO 2 reactivity. The action of inflammatory mediators on the endothelium h...

Ngày tải lên: 13/08/2014, 08:21

... injury? The interpretation of S-100β, a protein found predominately in astrocytes and Schwann cells, is difficult. Even when an increase in S-100β is not due to extracranial sources, includ- ing the ... PN, Shatney CH, Schein RM, Wilson MF, Sheagren JN, Hinshaw LB: Impact of encephalopathy on mor- tality in the sepsis syndrome. The Veterans Administration Systemic Sepsis Cooperative Stu...

Ngày tải lên: 13/08/2014, 11:22

... myocardial infarction were reduced. Hypotension was very instrumental in causing the adverse events. Interestingly, sepsis and infection were also clearly more common on metoprolol. Commentary Myocardial ... offset by an increase in cardiogenic shock (11 per 1,000) [7]. This was most prominent in the first day of therapy in elderly patients with tachycardia and low blood pressure, a p...

Ngày tải lên: 13/08/2014, 11:22

... Health Open Access Research Malaria control in Timor-Leste during a period of political instability: what lessons can be learned? Joao S Martins* 1,4 , Anthony B Zwi* 1 , Nelson Martins 1,2 and ... unknown. Malaria incidence typically increases in the rainy season (November to April). The national cumulative Annual Clinical Malaria Incidence (ACMI) based on syndro...

Ngày tải lên: 13/08/2014, 13:21

... limits acetylcholine production by the vagus nerve during sepsis. Since vagus nerve stimulation requires α 7 -nicotinic acetyl- choline receptors, direct activation of this receptor using nicotinic ... these studies, inhibition of NF-κB after partial hepatectomy results in massive hepatocyte apoptosis and impairs liver function. Conversely, NF-κB activation in the liver prevents hepatic i...

Ngày tải lên: 13/08/2014, 16:20

... exacerbate liver injury [9]. In addition to apoptosis, certain caspases, such as caspase-1, are involved in cytokine maturation by proteolytically proces- sing the inactive precursors of interleukin ... not apoptotic cells, is systemically elevated in human sepsis and functions as a mediator of endotoxin lethality in mice [12]. Intense research has recently delineated the sign...

Ngày tải lên: 13/08/2014, 18:22

... cerebral perfusion on brain function in sepsis. Sepsis and the brain In sepsis, the brain may be aff ected by many systemic disturbances, such as hypotension, hypoxemia, hyper- glycemia, hypoglycemia, ... brain and regulates brain capillary blood fl ow [1]. In sepsis, cerebral endothelial cells are activated by lipopoly- saccharide (LPS) and pro -in ammatory cytokines, including bra...

Ngày tải lên: 13/08/2014, 20:21

... severe sepsis and septic shock, the number of signifi cant diff erences in terms of the number of circulating NK cells, CD4 + T lymphocytes, CD8 + T lymphocytes, and B lymphocytes was limited ... Kranidioti H, Lignos M, Louis K, et al.: Early alterations of the innate and adaptive immune statuses in sepsis according to the type of underlying infection. Cri...

Ngày tải lên: 13/08/2014, 20:22

... concentrations of insulin-like growth factors-I and -II, alterations in insulin-like growth factor binding proteins, and induction of an insulin-like growth factor binding protein 3 protease. Crit ... gonadotropin secretion in critical illness: observations in postmenopausal women. Arch Intern Med 1989, 149:1637-1641. 20. Quint AR, Kaiser FE: Gonadotropin determinations and thy...

Ngày tải lên: 14/08/2014, 07:21

... Access Programmed death-1 levels correlate with increased mortality, nosocomial infection and immune dysfunctions in septic shock patients Caroline Guignant 1 , Alain Lepape 2 , Xin Huang 3 , Hakim ... not only may play a role in immune dysfunction but also may be an indicator of septic mor- tality and subsequent infectious episodes in septic patients...

Ngày tải lên: 14/08/2014, 08:21