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Báo cáo y học: " Hypertension may be the most important component of hyperdynamic therapy in cerebral vasospasm" pot

Báo cáo y học:

Báo cáo y học: " Hypertension may be the most important component of hyperdynamic therapy in cerebral vasospasm" pot

... methods of hyperdynamic therapy and speci c endpoints vary widely. A systematic review of clinical trials of the various techniques of hyperdynamic therapy and their e ects on cerebral ... hyperdynamic therapy are most important. Dankbaar and colleagues [1] provide a systematic review of clinical studies of hyperdynamic therapy and its components on CBF. Why focus on CBF instead of neurological ... rupture of an intracranial aneurysm [2,3].  e corner stone of medical therapy for cerebral vasospasm is so-called hyperdynamic therapy. Also referred to as triple-H therapy, this strategy includes...
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Báo cáo y học: "Can HRCT be used as a marker of airway remodelling in children with difficult asthma?" docx

... obtaining EB in children are thereforelimited. The potential to investigate the timing and natu-ral history of RBM thickening, and other features of airwayremodelling in children, would be increased ... manually by usingelectronic caliper endpoints (figures 1a and 1b). By esti-mating the Hounsfield units using the ROI (region of interest) tool, the endpoints were placed at the cut-offedge between ... the study of airwayinflammation in asthma [4]. In comparison, there hasbeen little interest in the development of similar tech-niques to study airway structural changes. One exceptionis the...
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Báo cáo y học: "Pre-existing disease: the most important factor for health related quality of life long-term after critical illness: a prospective, longitudinal, multicentre trial" docx

... quality of life after being in the ICU isattributable to pre-existing disease. The importance of the effect of pre-existing disease is further supported by the small, long term increment in the ... wi th the studygroup who were healthy before the intensive careperiod.HRQoL among patients dying during the follow up In total, 139 patients who were included in the studydied during the follow ... None of the studies cited above included pre-existing diseases in their analysis.Lastly,itmaybestressedthatthisstudybasedonHRQoL data gathered by two different, separate andvalidated HRQoL instruments,...
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Báo cáo y học: "Genomic analysis reveals the major driving forces of bacterial life in the rhizosphere" doc

... to participate in the synthesis of an as yet undefined secondary metabolite, wasinduced in the rhizosphere.Finally, it is worth noting the expression of genes pointingtowards potential DNA ... 64. In the combined analysis of the nine microarrays, P values wereadjusted for multiple testing to control the false discovery rate[13] or the type I family wise error rate by applying the ... plant exopolymers β-glucosidase, urease). The high induction of an urease accessory protein may be related to the limiting nitrogen source, since the nitrogen islikely being used by the plant....
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Báo cáo y học: " Exhaled breath condensate pH as a biomarker of COPD severity in ex-smokers" potx

... COPD in our study, in contrast to cur-rent smokers, is supported by previous findings suggest-ing that the inflammatory effects of current smoking may mask the underlying o ngoing inflammatory ... only in ex-smokers, after the elimination of the confounding role of continuing smoking. In this study, we have used as a cut-off point for th eexpression of severe hyperinflation, a value of the ... pH, including the effect of drinking or eating [24], smoking [25,26],thepresenceofextrapulmonarycomponents[27] ,the dilution bias and the purging procedure in order toachieve the stability of the...
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Báo cáo y học: "What should be the core outcomes in chronic pain clinical trials" ppt

... Turk1and Robert H Dworkin21Department of Anesthesiology, University of Washington, Seattle, Washington, USA2Department of Anesthesiology, University of Rochester, New York, USACorresponding author: ... inherentlysubjective. The only way to know about someone’s pain isby what they say or show by their behavior. There is anassumption that pain is highly associated with emotionaland physical ... well-being. In addition to relievingclinical symptoms and prolonging survival, a primaryobjective of any intervention is improvement of functioning.Physical functioningFunctional status typically...
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Báo cáo y học: " Pain may be inevitable; inadequate management is not" ppt

... mitigate against the perfect management of pain in the ICU, the first step is tomeasure the pain and to measure the response to initial therapy. Without this measurement, all of the downstreammeasures ... tomanagement of pain in the ICU is unclear. Opiates are usedroutinely [13], but their usefulness as analgesics for differentICU types of pain, their effects with longitudinal use, and theirinteractions ... downstreammeasures are probably in vain. Our challenge as a criticalcare community is to better serve our patients and theiroutcomes by evaluating and managing pain better. The recentarticle by Ahlers and...
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Tài liệu Báo cáo Y học: Dinucleoside polyphosphates stimulate the primer independent synthesis of poly(A) catalyzed by yeast poly(A) polymerase ppt

Tài liệu Báo cáo Y học: Dinucleoside polyphosphates stimulate the primer independent synthesis of poly(A) catalyzed by yeast poly(A) polymerase ppt

... catalyze the synthesis of a poly(A) chain in the absence of a primer [1]. In orderto explore whether the yeast enzyme also exhibited the same properties we assayed, in parallel, the activity of both ... independent synthesis of poly(A) In order to understand why dinucleoside polyphosphatesactivated the primer independent synthesis of poly(A), the effect of 0.01 mMGp4GorAp4A on the synthesis of poly(A) ... activity of GpnGs as effectors of the synthesis of poly(A)Based on the above results, the effect of several diguanosinepolyphosphates on the synthesis of poly(A) was comparat-ively studied. The...
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Báo cáo Y học: Structural basis for the inhibitory efficacy of efavirenz (DMP-266), MSC194 and PNU142721 towards the HIV-1 RT K103N mutant doc

Báo cáo Y học: Structural basis for the inhibitory efficacy of efavirenz (DMP-266), MSC194 and PNU142721 towards the HIV-1 RT K103N mutant doc

... alue thanobtained by others [9]. T his may be due to the use of homopolymeric rC-dG template in the assay. The assayshows that PNU142721 is the most potent of the threetowards the K103N mutant ... Efavirenz.Furthermore, wing2 composed of the heterocyclic ringstructure of MSC194 and the substituted pyrimidinefunctionality of PNU142721 occupy the same part of the NNIBP as the benzoaxine-2-one ring of Efavirenz. ... cornerstone in this therapy and arecommonly used in combination w ith inhibitors of the H IV-1protease. The RT inhibitors belong to two classes, the nucleoside inhibitors and the non-nucleoside inhibitors(NNRTI)....
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Báo cáo y học: "A 64-week, multicenter, open-label study of aripiprazole effectiveness in the management of patients with schizophrenia or schizoaffective disorder in a general psychiatric outpatient setting" pptx

... slightly better’ or ‘much better’ than the prestudy medication.Safety and tolerability Of the 245 subjects who were included in the safetysample, 163 (66.5%) experienced an AE during the switching ... subjects; of these, 9 were judged as being unlikely to be related tostudy drug, 14 as being unrelated to study drug, 11 a sbeing possibly related to study drug, and 9 as being prob-ably related ... aripiprazoledosing, the treating physicians could increase the dose of aripiprazole to a maximum of 30 mg/day. Dosingcould be reduced at any time due to tolerability. During the switching period (weeks...
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