Báo cáo y học: "Activated protein C ameliorates coagulopathy but does not influence outcome in lethal H1N1 influenza: a controlled laboratory study" potx

... Activated protein C ameliorates coagul- opathy but does not influence outcome in lethal H1N1 influenza: a con- trolled laboratory study Critical Care 2010, 14:R65 Schouten et al. Critical Care 2010, ... the influenza-induced rise in plasma and lung PAI-1 levels and partially preserving plasma and lung fibrinolytic activity. The capacity of APC to attenuate system...

Ngày tải lên: 13/08/2014, 20:21

Ngày tải lên: 13/08/2014, 01:20

... Region, Calgary, Alberta, T2L 2K8, Canada 3 Department of Community Health Sciences, University of Calgary and Calgary Health Region, Calgary, Alberta, T2L 2K8, Canada Corresponding author: Braden ... Braden J Manns 2,3 1 Department of Surgery, University of Calgary and Calgary Health Region, Calgary, Alberta, T2L 2K8, Canada 2 Department of Medicine, University of Calgary and Calgary Health...

Ngày tải lên: 13/08/2014, 08:20

... formation could prevent the activation of throm- bin activatable fi brinolysis inhibitor. Activated throm bin activatable fi brinolysis inhibitor inhibits the chemotactic factors C3 a and C5 a, which could ... [3]. APC was able to decrease coagulation activation and restore normal fi brinolysis compared with placebo but had marginal eff ects on cytokine levels, pulmonary neutrophil i...

Ngày tải lên: 13/08/2014, 20:22

... Physiology and Chronic Health Evaluation (APACHE) II score ≥25, or those in shock [7].  ere has Abstract Severe acute pancreatitis (SAP) is characterized by an unregulated systemic proin ammatory ... In the present issue of Critical Care, Pettila and colleagues report the fi rst single-centred pilot randomized controlled trial of activated protein C (APC) in alcohol- induced...

Ngày tải lên: 13/08/2014, 21:21

... Chest Physicians; American College of Emergency Physicians; Canadian Critical Care Society; European Society of Clinical Microbiology and Infectious Diseases; European Society of Intensive Care ... time. Sadaka et al. Critical Care 2011, 15:R89 http://ccforum.com/content/15/2/R89 Page 3 of 7 RESEARCH Open Access Activated protein C in septic shock: a propensity-matched analysis Farid...

Ngày tải lên: 14/08/2014, 07:21

... former. In addition, TC measurements may be inherently less variable over time for physiological reasons and also because TC is mea- sured in a laboratory by using standardized assays that have small ... activity, medications, intercurrent infections, smoking, and diabetes were rou- tinely collected according to a set protocol. The data were stored and tracked in the lupus databas...

Ngày tải lên: 12/08/2014, 14:22

... reduce oxygen con- sumption (heart rate, blood pressure and minute volume are measured continuously); and to reduce physical resistance to and fear of medical examination and daily care. According ... 25:930-935. 9. Villar J, Perez-Mendez L, Aguirre-Jaime A, Kacmarek RM: Why are physicians so skeptical about positive randomized controlled clinical trials in critical care medicine? Intens...

Ngày tải lên: 13/08/2014, 08:20

... Geeraert A, Malcus C, Poitevin F, Bohé J, Lepape A, Ayala A, Monneret G: Increased circulating regulatory T cells (CD4(+)CD25 (+)CD127 (-)) contribute to lymphocyte anergy in septic shock patients. ... be important to the Th1/Th2 cytokine balance in burned patients and sepsis patients. Abbreviations ANOVA: analysis of variance; bp: base pair; CTLA-4: cytotoxic T-lymphocyte- associa...

Ngày tải lên: 13/08/2014, 20:21

... ation trial. Abbreviations ALI: acute lung injury; ANOVA: analysis of variance; ARDS: acute respiratory distress syndrome; Cdyn: dynamic compliance; CT: computed tomography; FiO 2 : fraction of inspired ... monitoring of reactance and investigating the feasibility of a reactance based trigger for RMs. Considering that the optimization procedure based on Xrs can be easily integrated in com...

Ngày tải lên: 14/08/2014, 08:21