... YG, Christen WG, Foster SC: Correlation of metal-loproteinase-2 and -9 with proinflammatory cytokines inter-leukin-1β, interleukin-12 and the interleukin-1 receptorantagonist in patients with ... inflammation,resulting in fibrosis. MMP-9 can trigger inflammationdirectly, by tissue destruction, or indirectly, by generation ofan inflammatory signal or recruitment of inflammatory cells[32]. Infiltration ... with theincreased MMP-9 activity [30]. Similarly, in response to ble-omycin, mice deficient in γ-glutamyl transpeptidase showeda reduction in pulmonary fibrosis, in part associated with lower...