... patients with RA and patients with SLE showed significant differences in their chemokine receptor expression when compared with B cells from healthy individuals and also from patients with OA. In patients ... residual synovial-lining cells and infiltrating leuko- cytes are the source of pro-inflammatory chemokines such as CCL2, CCL3, CCL5, CCL20, CXCL9 and CXCL10,...
Ngày tải lên: 09/08/2014, 06:23
... levels in osteoarthritic equine knee joints during ACS treatment in vivo [14]. However, in the Figure 6 Cytokine levels in control serum and ACS, and in synovial fluid during treatment. Control serum ... determined in the current study, in the joint space. With respect to the role of Il-1 signalling in OA, in the one human clinical study using recombinant IL-1ra...
Ngày tải lên: 12/08/2014, 14:22
Báo cáo y học: "Dialectical Behavioral Therapy for Adolescents (DBT-A): a clinical Trial for Patients with suicidal and self-injurious Behavior and Borderline Symptoms with a one-year Follow-up" pot
... irritability, or anxiety usually lasting a few hours and only rarely for more than a few days) 12 10 Chronic feelings of emptiness 8 3 Inappropriate, intense anger or difficulty in controlling anger ... families participating in this study for teaching us about resilience, dedication and courage. Author details 1 Division of Child and Adolescent Psychiatry and Psychotherapy, Depar...
Ngày tải lên: 13/08/2014, 18:21
Báo cáo y học: "Raloxifene reduces urokinase-type plasminogen activator-dependent proliferation of synoviocytes from patients with rheumatoid arthritis" docx
... reducing u-PAR levels in healthy and RA syn- oviocytes (p < 0.01). The effect of 0.5 µM and 1 µM RAL is significantly higher in RA than in healthy synoviocytes (p < 0.05). Radioligand binding ... as an inhibitor of the fibrinolytic system, exhibiting similar effects on both healthy and RA synoviocytes, with the activity on RA syn- oviocytes being more pronounced. Indeed, t...
Ngày tải lên: 09/08/2014, 07:20
Báo cáo y học: " Dynamic analysis of CD127 expression on memory CD8 T cells from patients with chronic hepatitis B during telbivudine treatment" ppt
... cells increased significantly in CHB patients compared with healthy controls. Importantly, theabsoluteCD127 - memory T-cell count increased markedly in CHB patients as well, while only a small increase ... provided analytical tools and were also involved in editing the manuscript, YYD designed the study and wrote the manuscript. Competing interests The authors declare that the...
Ngày tải lên: 12/08/2014, 01:21
Báo cáo y học: "Risk stratification of early admission to the intensive care unit of patients with no major criteria of severe community-acquired pneumonia: development of an international prediction rule" potx
... restricted to patients requiring IRVS [19]. Indeed, ICU care has been demonstrated to improve outcome in severely ill and unstable patients, and these patients require intensive moni- toring and may potentially ... E, Fine MJ: Investigation of the ability of the Pneumonia Severity Index to accurately predict clinically relevant outcomes: a European study. Clin Microbiol Infect 20...
Ngày tải lên: 13/08/2014, 16:20
Báo cáo y học: "Matrix-metalloproteinase-2, -8 and -9 in serum and skin blister fluid in patients with severe sepsis" potx
... levels of MMP-2 and MMP-8 were up-regulated in severe sepsis both in skin blister fluid and in the serum, MMP-2 levels were higher in skin blister fluid as well as in serum in more severe organ ... timely development of serum and skin MMP-2, -8 and -9 levels in human severe sepsis and their association with disease severity and mor...
Ngày tải lên: 13/08/2014, 20:21
Báo cáo y học: " Glycine tomentella Hayata inhibits IL-1b and IL-6 production, inhibits MMP-9 activity, and enhances RAW264.7 macrophage clearance of apoptotic cells" docx
... stimulation with LPS as described and the activity of MMP-2 and MMP-9 was analyzed by gelatin zymography. We found the activity of MMP-9, but not MMP-2, was sig- nificantly inhibited by GTH treatment in ... epi- catechin, naringin, riodictyol , daidzein, glycitein, nari- genin, luteolin, genistein, hesperetin, and isorhamnetin could be determined in GTH. The major components of GT...
Ngày tải lên: 10/08/2014, 05:21
Báo cáo y học: "Early Inhibition of NF-κB activation and MMP-9 secretion by plasma of human volunteers after ingestion of maritime pine bark extract (Pycnogenol)" pot
... δ-(3,4-dihydroxy-phenyl)-γ-valerolactone and δ-(3-methoxy-4-hydroxy-phenyl)-γ-valerolactone exhibited inhibitory activity on LPS-induced secretion of matrix metalloproteinase 9 (MMP-9) from human mono- cytes ... monocytes were incubated with plasma obtained after 5 days Pycnogenol intake. The plasma of all study five participants exhibited an inhibi- tory effect on LPS-induced NF-κB activ...
Ngày tải lên: 11/08/2014, 08:21
Báo cáo y học: "Spinal Intramedullary Cysticercosis: A Case Report and Literature Review"
... thoracic spine showing a relatively well defined cystic intramedullary lesion with hypointense on T1WI and hyperintense on T2WI. Figure 2. Photomicrographs of the histological specimen showing ... a subtle hypointense rim may sur- round the intramedullary cyst on T2WI. In the col- loidal stage the thickened cyst capsule is hyperintense on T1WI and hypointense on the T2WI. Cyst...
Ngày tải lên: 25/10/2012, 10:56