... binding a nities, and the hypocalcemic potencies in vivo of hCt, sCt, analogues 1–6 and/ or the partial sequence analogues 1a, 1b, 2a, and 3a. The CD data of the partial sequence analogues 1a, ... potencies in vivo of hCt,sCt, analogues 1–6 and/ or 1a, 1b, 2a, and 3a are summa-rized in Table 1. Our findings that 3 and 4, that contain typeIandII¢ b-turn-promoting substitutes, had the samehypocalcemic ... 789Conformationally constrained human calcitonin (hCt) analoguesreveal a critical role of sequence 17–21 for the oligomerizationstate and bioactivity of hCtAthanasios Kazantzis1, Michaela Waldner1,...