... differences in severity ofbrain oedema and in associated hypoxia and herniation,thereby introducing bias into the interpretation of the results.MRS findings vary greatly according to time since TBI. ... correlate with severity of the initial injury or the existence of herniation, another possibility is that they directly contribute to the prognosis. Studiesinvolving multimodal investigations would ... Hypersignals in the cortex, Hypersignals in the cortex, Hypersignals of the cortex, Normal or possible in the thalamus and in the in the thalamus and in the the thalamus, the basal ganglia hypersignals...