Báo cáo y học: "Effect of dexmedetomidine versus lorazepam on outcome in patients with sepsis: an a priori-designed analysis of the MENDS randomized controlled trial" doc

... pro- and anti-inflammatory cytokines, decreasedglucose tolerance and increased insulin resistance andactivation of the hypothalamic-pituitary axis [26]; all of these can contribute to worse clinical ... analyzed using an intention-to-treat approach.Continuous data were described using medians andinterquartile ranges or means and standard deviations,and categorical data using frequencies and proportions.We ... Ivanova A, Henderson AG, Pohlman A, Chang L, Rich PB, Hall J: A randomized trial of intermittent lorazepam versus propofol with daily interruption in mechanically ventilated patients. Crit Care...

Báo cáo y học: " Low central venous saturation predicts poor outcome in patients with brain injury after major trauma: a prospective observational study" pot

... capil-lary leakage, microcirculatory disturbances, metabolicalteration, imbalance of pro- and anti-inflammatorymechanisms, ischaemia/reperfusion injury, coagulationdisturbances [1]. In major ... purposes)Scandinavian Journal of Trauma, Resuscitation and Emergency MedicineOpen AccessOriginal researchLow central venous saturation predicts poor outcome in patients with brain injury after major ... col-lected data and helped draft the manuscript. GZ revised the manuscript. All authors have seen and approved the final revised version.Additional materialAdditional file 1Appendix on trauma. Major...

Báo cáo y học: "Functional impairment related to painful physical symptoms in patients with generalized anxiety disorder with or without comorbid major depressive disorder: post hoc analysis of a crosssectional study" docx

... several limitations; the mainlimitation is that the analysis is focused mainly on corre-lations and associations, but does not provide any causalrelationships. The results of the analysis cannot ... qualitativevariables and by analysis of variance (ANOVA) for quan-titative variables. The associations between the presence of PPS andfunctioning in the different groups of diagnoses (GAD+MDD+; GAD+MDD-; ... well in a range of activities or areas. However, thistask may not be as easy as it appears, given that function-ing and pain symptoms are not commonly or systemati-cally measured during the management...

Báo cáo y học: "Trace Elements, Heavy Metals and Vitamin Levels in Patients with Coronary Artery Diseas"

... with increased foam cell formation and atherosclerosis, though other mecha-nisms may exist (4). Each antioxidant has different and important mechanisms of action since oxidative damage can ... of humans to Mn. The urine of CAD patients also shows higher Mn concentrations than that of healthy controls (24). In atherosclerotic sub-jects, the Mn content of the heart and aorta of athero-sclerotic ... varia-tion in the urinary excretion of electrolytes and trace elements in men. Am J Anat. 1983; 166: 121-148. 25. Volkov NF. The cobalt, manganese and zinc content in the blood and internal...

Báo cáo y học: " Sigma-1 receptor agonist fluvoxamine for delirium in patients with Alzheimer’s disease pot

... Y, Sakata M, Naganawa M, Oda K,Miyatake R, Fujisaki M, Shimizu E, Shirayama Y, Iyo M, Hashimoto K: Highoccupancy of sigma-1 receptors in the human brain after single oraladministration of fluvoxamine: ... infarcts in the brain. N-isopropyl- [123I]* Correspondence: furuse@asahikawa-rch.gr.jp1Department of Psychiatry, Asahikawa Red Cross Hospital, Asah ikawa, JapanFuruse and Hashimoto Annals ... ForensicMental Health, Chiba, Japan.Authors’ contributionsTF contributed to the clinical and rating evaluations during the follow-upperiods. KH conceived of the study and participated in its study andcoordination....

Báo cáo y học: "Switching from serotonin reuptake inhibitors to agomelatine in patients with refractory obsessive-compulsive disorder: a 3 month follow-up case series" doc

... availability of agomelatine, a novel anti-depressant acting as a melatonin agonist and selectiveserotoni n antag onist (MAS SA; acting against melatonin1 (MT1) and MT2, and 5-hydroxytryptamine (HT)2C,respectively) ... continuation of agomelatine.Finally, despite a number a methodological and clini-cal constraints and the very preliminary nature of the results, further controlled studies are warranted toassess ... personalhistoryofPDwithepisodicattackssincetheageof18.She had a history of repetitive failure on antidepressanttrials, with the last one being the SNRI duloxetine120mg/dayandtheBDZclonazepam4mg/dayfor3monthsplusCBTfor6months.Atbaseline,her Y- BOCS...

Báo cáo y học: "Inflammation predicts accelerated brachial arterial wall changes in patients with recent-onset rheumatoid arthritis" pptx

... 31 patients with early RA at baseline and one yearBrachial dilatation of 20 patients with early RA and matched controls, and of 31 patients with early RA at baseline and one year. Flow-medi-ated ... 52 years of age, two males with a history of angina at the ages of 48 and 64 years, and one patient with myocardial infarction (MI) at age 48 years. Twenty of these RA patients could be matched ... months in RA patients and the change in each parameter was calculated. Datawere analysed by univariate regression.Results Mean FMD and GMD were significantly lower in earlyRA patients at baseline...

Báo cáo y học: "Anti-C1q antibodies antedate patent active glomerulonephritis in patients with systemic lupus erythematosus" pot

... World Health Organization andInternational Society of Nephrology/Renal Pathology Society[21]. The renal disease was class IV in 14 patients and classV in one patient. In the remaining 55 patients ... range was only 2 years(three patients, including one patient with a very high anti-C1qtiter). With the caveat that we studied only a small number of patients, and that we studied only a single ... discrepancy may be ascribable to differences in the patient populations and anti-C1q assays. In the study by Fangand colleagues, the IgG subclass distribution of anti-C1q anti-bodies suggested that...

Báo cáo y học: "Preliminary speech recognition results after cochlear implantation in patients with unilateral hearing loss: a case series." pdf

... Caucasian German men, two aged 48 and the others aged 51 and 57 years old, with post-lingual unilateral hearing loss and normal hearing on the contralateral side were implanted with a cochlearimplant. ... hismiddle ear status was normal. He had a duration of deafness of 11 months before unilateral implantation with a CI. Patient S2 was a 51-year-old Caucasian Ger-man man also with post-lingual UHL and ... middle earstatus. Patient S3 was implanted unilaterally with a CIafter a duration of deafness of 96 months. Patient S4was a 57-year-old Caucasian German man with post-lin-gual UHL and NH on his...

Báo cáo y học: "Endothelial cell markers reflecting endothelial cell dysfunction in patients with mixed connective tissue disease" doc

... had acutemyocardial infarction, or had ECG signs of myocardialinfarction, recorded semi-annually; the coronary diseasewas treated with coronary bypass operation or angio-plasty; or angina was ... AHperformed interpretation of the data and drafted the manuscript. GP and GSperformed analysis and interpretation of the data. EB gave final approval of the version to be published. All authors read and ... the vascular protectionis essential in patients with MCTD, especially in Ray-naud's penomenon and PAH, and also aspirin and statintherapy is important from the early stage of MCTD.Carotid...

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