Báo cáo y học: "Bench-to-bedside review: The role of β-lactamases in antibiotic-resistant Gram-negative infections" potx

... appropriate ther- apy, and use of the procedure will probably become the standard of care in the next few years. Indicators of prognosis CAP is the leading cause of death from infection in west- ern ... by egress of lipopolysaccharide found in the lumen of the gut from endogenous enteric Gram-negative bacteria into the systemic circulation [29].  e host r...

Ngày tải lên: 13/08/2014, 19:20

... Capacity (including staffing) How do we ensure that security (including checking of staff identity) is maintained? Who is the lead intensivist and who is the senior nurse? Are their roles clearly ... explosive-type disaster yields low numbers of critically injured patients, over-triage is likely to be a problem, with the attendant risk of increasing overall mortality [12]. On the...

Ngày tải lên: 13/08/2014, 10:20

... programmes use iNO routinely during early reperfusion of the lung. Bearing in mind that the concept of ischaemia/reperfusion injury in clinical transplantation also embodies the state of the donor ... role of surfactant in management of initially impaired graft function after lung transplantation, and do these findings apply to other forms of lung injury? Ischaemia...

Ngày tải lên: 12/08/2014, 18:21

... hypertension [29,43–45]. In addition to activation of the renin–angiotensin system, vasopressin, endothelin, and catecholamines are postulated to play important roles in the pathophysiology of ... pressure may result in further infarction involving the entire territory of that artery. The current recommendation of the American Heart Association is that hypertension in...

Ngày tải lên: 12/08/2014, 19:22

... combination. The single exception is the addition of weak base (e.g. tris-hydroxymethyl aminomethane) [6], which is normally absent from body fluids. Review Clinical review: The meaning of acid–base ... support of this statement Plasma-Lyte 148 priming cardiopulmonary bypass pumps has been shown to increase arterial base excess by the end of bypass [25]. On the other hand,...

Ngày tải lên: 12/08/2014, 20:20

... of the incubator. The noise was reduced by 3.3 dBA inside the incubator. In a study by Blomkvist and colleagues [48], after the replacement of the ceiling tiles the noise level was reduced by ... [53] to test the effect of night and day on infants in a newborn nursery. Besides turning off the radio, lights and covering the windows with thick and dark curtains, the...

Ngày tải lên: 13/08/2014, 11:23

... insulin resistance, induction of SLPI locally in adipose may also play a role in the prevention of inflammation-induced insulin resistance. In summary, we have demonstrated that obesity is accompanied by increased ... mechanism by which SLPI counteracts inflam- mation in adipocytes. Discussion Inflammation plays a major role in obesity-induced insu- lin resistance by the...

Ngày tải lên: 11/08/2014, 03:20

... activated in adipose tissue in obesity [12,13], the induction of SLPI in adipose tissue during obesity may be influenced by the activation state of the TLRs. Higher expression of SLPI in the visceral ... anti-inflammatory response to counter localized inflammation in these depots. Because visceral adiposity is linked to insulin resistance, induction of SLPI locally...

Ngày tải lên: 11/08/2014, 06:22

... easier. In our study only 10.7% of participants withdrew from the study: this surprisingly positive finding may be explained in terms of perceived quality of care related to the offering of custom-made ... provided preliminary evidence for the safety, feasibility, and efficacy of exercise training in breast cancer survivors. The aim of this study was to assess...

Ngày tải lên: 08/08/2014, 16:23

... generally stable to hydrolysis by all other β-lactamases that have serine at the active site of the enzyme [11]. Early reports of this group of chromosomal enzymes were from single isolates of ... strains [38]. Although these enzymes are structurally related to the older OXA β-lactamases, these new members of the OXA family have carbapenem-hydrolyzing activity. Becau...

Ngày tải lên: 13/08/2014, 20:21