Báo cáo y học: "New versus old blood – the debate continues" docx

... the clinical impact of the duration of red blood cell storage prior to transfusion remains uncertain, and a topic of growing interest. © 2010 BioMed Central Ltd New versus old blood – the debate ... further data – the Age of Blood Evaluation study (Canadian Clinical Care Trials Group) in trauma/ intensive care patients and the Red Cell Storage Age Study (US...

Ngày tải lên: 13/08/2014, 20:21

... Only the emergency physician enrolling patients was aware of group assignment.  e primary endpoint was the maximum score of the sequential organ failure assessment during the fi rst 3 days ... emergency intubation were prospectively enrolled from 12 emergency medical services or emergency departments and 65 intensive care units in France. Patients were randomly assigned by a co...

Ngày tải lên: 14/08/2014, 07:21

... into any of the known sub- types or CRFs after RT phylogenetic analysis, have also been observed since 1996. The objective of our study was to characterize more in detail these strains. Phylogenetic analysis ... Phylogenetic analysis of their V3-V5 env region has been performed and 3 of them were full-length sequenced, as they seemed par- ticularly divergent. Methods Study population The...

Ngày tải lên: 13/08/2014, 05:21

... consid- ered carefully. The use of lightweight, large-pore polypropylene meshes appears to reduce the risk of any major foreign-body reaction that might lead to shrinkage of the mesh area or to ... the donor site completely [6], and new techniques, which pre- serve the anterior rectus sheath are limited in their use by anatomic variations [2]. In addition to the aesthetic disturba...

Ngày tải lên: 11/08/2014, 23:21

... so far used [4]. The data presented by Sharma and colleagues in the previous issue of the journal and the previously quoted Australian study support that SpA as well as other autoimmune diseases ... subsets – namely, AS, psoriatic arthritis, reactive arthritis, arthritis associated with inflammatory bowel disease, and undifferentiated spondyloarthropathy – and have been...

Ngày tải lên: 12/08/2014, 11:22

... pupil reactivity, and the univari- ate analysis did not identify differences between them. There- fore, these were not included in the multivariate analysis. The logistic regression analysis showed ... different dosages employed in the two arms of the study. However, the present study is useful as a hypothesis testing exercise and will help to inform the design of future studies...

Ngày tải lên: 13/08/2014, 11:22

... and analyzed the responses qualitatively. The project was approved by the Baylor College of Medicine Institutional Review Board. The final survey included these items: 1. What has been your ... simply bureaucracy. They often are most puzzled by statements such as denial that an institution will pay for medical costs if they are injured in a study, when their participation simpl...

Ngày tải lên: 08/08/2014, 17:20

... but they are needed only in oxidative stress conditions, as shown by the fact that deletion mutants show the same survival as wild-type cells under heat shock. Fritz Roth (Harvard University, ... described the use of the methylo trophic yeast Pichia pastoris in metabolic engineer ing for the production of proteins (human antibodies) by secre tion. The P. pastoris genome is f...

Ngày tải lên: 09/08/2014, 20:20

... Using a hydrazide-based chemistry to selectively enrich for N-linked glycopeptides by affinity purification, a 20-fold reduction in sample complexity was achieved. Many of the glycosylated proteins ... strategy, further demonstrated by Ruedi Aebersold (also at the Institute for Molecular Systems Biology), that alleviates some of the current limitations. The first step consists of the...

Ngày tải lên: 14/08/2014, 07:21

... many other biological systems: the Ras family of GTPases is but one example. A persistent question and the genesis of significant debate within the innate immunity field is the mechanism by which these ... from the membrane by viral proteases, as in the case of deactivation of MAVS by the hepatitis C virus protease NS3/4A, completely destroys the function of these proteins [...

Ngày tải lên: 14/08/2014, 08:21