Báo cáo y học: "Cerebral perfusion in sepsis" pot
Báo cáo y học: "Cerebral perfusion in sepsis" pot
... cerebral perfusion
on brain function in sepsis.
Sepsis and the brain
In sepsis, the brain may be aff ected by many systemic
disturbances, such as hypotension, hypoxemia, hyper-
glycemia, hypoglycemia, ... brain and regulates brain capillary blood fl ow [1]. In
sepsis, cerebral endothelial cells are activated by lipopoly-
saccharide (LPS) and pro -in ammatory cytokines,
including bra...
Báo cáo y học: "Cerebral perfusion in sepsis-associated delirium" pdf
... injury?
The interpretation of S-100β, a protein found predominately in
astrocytes and Schwann cells, is difficult. Even when an
increase in S-100β is not due to extracranial sources, includ-
ing the ... PN, Shatney CH, Schein RM, Wilson MF,
Sheagren JN, Hinshaw LB: Impact of encephalopathy on mor-
tality in the sepsis syndrome. The Veterans Administration
Systemic Sepsis Cooperative Stu...
Báo cáo y học: "Myocardial protection in sepsis" potx
... myocardial infarction were
reduced. Hypotension was very instrumental in causing the
adverse events. Interestingly, sepsis and infection were also
clearly more common on metoprolol.
Commentary
Myocardial ... offset by an increase in
cardiogenic shock (11 per 1,000) [7]. This was most
prominent in the first day of therapy in elderly patients with
tachycardia and low blood pressure, a p...
Báo cáo y học: "Brain dysfunction in sepsis: what can we learn from cerebral perfusion studies" pdf
... the
effect of inflammatory mediators on the brain.
Investigations addressing SAD will remain difficult due to the
problem of correctly identifying and quantifying this entity.
The value of monitoring cerebral ... one could speculate that, in analogy to
traumatic brain injury, severe brain dysfunction is necessary
to disturb CO
2
reactivity. The action of inflammatory
mediators on the endoth...
Báo cáo y học: "Cerebral involvement in a patient with Goodpasture''''s disease due to shortened induction therapy: a case report" pdf
... purposes)
Introduction
In Goodpasture's disease, a type II hypersensitivity reac-
tion is present with antibody and T-lymphocyte reactivity
to the NC1 domain of the alpha3 chain of type 4 collagen
[1]. ... microbleeds in combination with a gas-
trointestinal reflux disease. Cyclophosphamide therapy
was reintroduced with monthly administration of 1 g as a
bolus, initially. Immunosuppr...
Báo cáo y học: "Coagulation cascade in sepsis: getting from bench to bedside" pot
... basic research. The
potential key role of proteins that were originally believed to
be exclusively involved in coagulation in the inflammatory
response provides an exciting potential mechanism(s) ... augmenting or inhibiting the contribution of the
clotting cascade components to inflammation would be
required for determining the selection and dosing of potential
new therapies.
Altering th...
Báo cáo y học: "Neuroimmune perspectives in sepsis" pps
... limited by a potential cholinergic attrition that limits
acetylcholine production by the vagus nerve during sepsis.
Since vagus nerve stimulation requires α
7
-nicotinic acetyl-
choline receptors, ... these
studies, inhibition of NF-κB after partial hepatectomy results
in massive hepatocyte apoptosis and impairs liver function.
Conversely, NF-κB activation in the liver prevents hepatic
in...
Báo cáo y học: "Cell death in sepsis: a matter of how, when, and where" potx
... and
actually exacerbate liver injury [9].
In addition to apoptosis, certain caspases, such as caspase-1,
are involved in cytokine maturation by proteolytically proces-
sing the inactive precursors of interleukin ... Neverthe-
less, these promising findings must be tempered by the new
study showing that multiple pathways might be activated in
dying cells during sepsis [1]. The simple inh...
Báo cáo y học: " Immune status in sepsis: the bug, the site of infection and the severity can make the difference" docx
... erences in terms of the number of circulating NK
cells, CD4
+
T lymphocytes, CD8
+
T lymphocytes, and B
lymphocytes was limited to community-acquired pneu-
monia and intra-abdominal infection. ... ammatory responses in the
early phase of severe sepsis: longitudinal study of mononuclear
histocompatibility leukocyte antigen-DR expression, procalcitonin,
C-reactive protein, and change...
Báo cáo y học: " Watching proteins in motion" pot
... annual symposium of the Protein Society
highlighted the dynamic motions that enable almost all
protein function. The ability of polypeptide protein chains
to adopt intricate and highly-defined ... polariza-
bility at multiple positions within staphylococcal nuclease.
Polarizability was determined by introducing ionizable
amino acids and measuring their pK
a
shift. The data
obtained fro...