Báo cáo y học: "Argon: Neuroprotection in in vitro models of cerebral ischemia and traumatic brain injury" pdf

... traumatic brain injury and stroke are widespread and generate an enormous economic and social burden, we investigated the possible neuroprotective effect in in vitro models of traumatic brain injury and ... effect in both in vitro models of oxygen-glucose deprivation and traumatic brain injury. Our promising results justify further in vivo animal rese...

Ngày tải lên: 13/08/2014, 20:21

... to the difficulty in detecting diffuse axonal injury [34,35] and lesions of the brainstem [2]. Recently, research into the value of imaging for prognosis has focussed on the brainstem. Here, Magnetic ... mortality and severe morbidity in young adults in industrialized countries, for example, in Germany 30,000 peo- ple suffer from severe brain trauma each year. A total of 1...

Ngày tải lên: 13/08/2014, 20:21

... Bal 1,2 1 Faculty of Chemistry, University of Wroclaw, Poland; 2 Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Warsaw, Poland A comparative study of thermodynamic and kinetic aspects of ... aspects of Cu(II) and Ni(II) binding at the N-terminal b inding site of human and bovine serum albumins (HSA and BSA, respectively) and short peptide ana...

Ngày tải lên: 22/02/2014, 04:20

... early intervention will assist in reducing symptoms of traumatic stress as well as preventing chronic disorder and disability in children experiencing acute PTSD following accidental injury. Trial ... emotional numbing or avoidance of reminders of that event and physiological hyperarousal. Children and adolescents may experience PTSD following exposure to a wide vari- ety o...

Ngày tải lên: 11/08/2014, 16:22

... details 1 Centre of National Research on Disability and Rehabilitation Medicine, School of Medicine, University of Queensland, Herston QLD 4029, Australia. 2 School of Psychology, University of Queensland, ... controlled trial of risk screening and early intervention comparing child- and family-focused cognitive-behavioural therapy for PTSD in children following accidental...

Ngày tải lên: 11/08/2014, 16:23

... to easily partition into the brain and are able to fi t snugly into amphiphilic binding cavities within proteins [9]. Depending on the properties of the surrounding electrons, some of the noble ... argon may have therapeutic properties for neuronal toxicity by demonstrating protection against both traumatic and oxygen-glucose deprivation injury of organotypic hippocampal c...

Ngày tải lên: 13/08/2014, 20:21

... Chemical Biology Division, Department of Biological and Environmental Science, University of Jyväskylä, Jyväskylä, Finland 5. Division of Rheumatology, Department of Medicine, Pennsylvania State ... ecdysone recep - tor plasmid pVGRXR (Invitrogen) into the cells using Lipofectamine (Invitrogen) and PLUS reagent (Invi- trogen). Expression of GFP/NS1 or GFP was induced by the...

Ngày tải lên: 25/10/2012, 11:18

... specific arginine residues (R394 and R396 for b-arrestin2) in b-arrestin that mediate its binding to AP2 were identified [23]. The presence of the clathrin-binding domain and AP2 binding site in Ci-Arr ... specifically phosphorylated by G protein- coupled receptor kinases (GRKs) and then bind to arrestins to preclude the receptor/G protein interaction, resulting in quenching of t...

Ngày tải lên: 31/03/2014, 08:20

... homozygous in gDNA and yet heterozygous in cDNA, and the median coverage for these SNVs in gDNA was only 12×, compared to 28× for SNVs that matched for zygosity. It is likely that many of the ... SNVs in pro- tein-coding exons in gDNA and 64,128 in cDNA. Of these, 48,740 in gDNA and 40,605 in cDNA passed qual- ity control filters, and 19,054 of these overlapped...

Ngày tải lên: 09/08/2014, 20:22

... immunity is impor- tant, with increased CD8 T lymphocytes and inflamma- tory cytokines (notably INFγ and IL-10) found in involved tissues [13,14]. IPH may represent aberrant immune activity, triggered ... coexpression of proinflammatory and down-regulatory cytokines in intestinal T cells in child- hood celiac disease. Gastroenterology 2002, 123:667-678. 14. Alaedini A, Green PH...

Ngày tải lên: 11/08/2014, 20:20