Báo cáo y học: "β2 adrenergic agonists in acute lung injury" ppsx

... in the majority of patients with acute lung injury and the acute respiratory distress syndrome. Am J Respir Crit Care Med 2001, 163:1376-1383. 7. McAuley DF, Frank JA, Fang X, Matthay MA: Clinically ... 60-day mortality between treatment groups. The study was stopped by the Data Monitoring Board at the first interim analysis for futility following 279 patients who received the study d...

Ngày tải lên: 13/08/2014, 20:21

... Pulmonology, and Nephrology, Yamagata University School of Medicine, Yamagata, Japan 2. Division of Clinical Laboratory, Yamagata University Hospital, Yamagata, Japan  Corresponding author: Dr. Yoko ... pneumo- nia, infiltrating neutrophils produce pro-inflammatory cytokines and chemokines, result- ing in the induction of cellular adhesion molecules on circulating leukocytes and pulmon...

Ngày tải lên: 08/08/2014, 18:21

... pathogenesis of acute lung injury in humans. The first of these, namely the ‘neutrophilic hypothesis’, suggests that during acute inflammation the cytokines granulocyte colony-stimulating factor and granulocyte/macrophage ... outcome in acute lung injury. Phagocytosis of apoptotic neutrophils and release of cytokines by macrophages The third mechanism whereby apoptosis of neutro...

Ngày tải lên: 12/08/2014, 19:22

... of such systems outside the conventional indication of acute life-threatening hypoxemia. Ever since its original description by Daniel Ashbaugh and co-workers in 1967 [2], hypoxemia in spite ... widening indications with the aim of reducing ventilator induced lung injury (VILI) is still controversial. Consequently, technological progress is an important strategy. Miniaturized ECM...

Ngày tải lên: 13/08/2014, 20:21

... sensitivity and specificity, the ability of VPW to discriminate fluid status in patients with acute lung injury is limited and should only be considered when intravascular pressures are unavailable. Introduction The ... LVEDV is widely presumed, this is not the case in a number of conditions pertinent to acute lung injury, including sep- sis [25-27], trauma [28], and acute respi...

Ngày tải lên: 14/08/2014, 07:21

... considered as an insult fre- quently leading to systemic inflammatory response syn- drome including the systemic release of proinflammatory cytokines which is central in t he inflammatory response. Previous ... frequently induces a s ystemic inflammatory response syndrome (SIRS) that results in multiple-organ dysfunction syndrome (MODS) [1,2] including acute lung injury (ALI), which i...

Ngày tải lên: 10/08/2014, 09:21

... with acute lung injury and to 29/33 (88%) of those with acute respiratory distress syndrome. Lung injury patients had higher mortality than others (acute lung injury 25.0%; acute respiratory distress ... to lung injury, both inside and outside the intensive care unit. Patients were followed prospectively for outcomes, including the diagnosis of acute lung injury or acute...

Ngày tải lên: 13/08/2014, 08:20

... clinical outcomes. Albumin with furosemide benefits lung physiology in hypoproteinemic patients with acute lung injury /acute respiratory distress syndrome, but the independent pharmacologic ... determine the independent pharmacologic effects of albumin and furosemide in hypoproteinemic patients with acute lung injury /acute respiratory distress syndrome. Design: Random...

Ngày tải lên: 13/08/2014, 08:20

... locus previously identified in a multiplex family study [2]. UBASH3B and UBAC2 encode ubiquitin-associated proteins. The ubiquitin system is best described in targeting misfolded or damaged proteins for ... easy for a rare condition such as BD. The authors addressed this point by performing the initial analysis on pooled samples and then, having identified potential SNPs, validating the f...

Ngày tải lên: 09/08/2014, 14:22

... shock. Figure 5 Individual changes in mean pulmonary artery pressure (MPAP) and PaO 2 /FiO 2 induced by increasing inspiratory intratracheal concentrations of inhaled NO (Insp IT NO) in eight patients ... dopamine, epine- phrine or norepinephrine tend to reinforce hypoxic pulmonary vasoconstriction. In the present study, patients with circulatory shock receiving vasodilating inotrops...

Ngày tải lên: 12/08/2014, 18:20