Báo cáo y học: " Ventilator-induced endothelial activation and inflammation in the lung and distal organs" docx

... project running and data analysis, and drafted the manu- script. TM, SF, YI, YK, and HM assisted in the study design and coordination, and oversaw the data analysis and drafting of the manuscript. ... interests The authors declare that they have no competing interests. Authors' contributions HI and MJ designed the study. NHK, MT, YY, and FCM assisted in t...

Ngày tải lên: 12/08/2014, 14:22

... shown). Figure 2 Ventilator-induced endothelial activation and inflammation in pulmonary tissueVentilator-induced endothelial activation and inflammation in pulmonary tissue. In total lung homogenates, ... may cause endothelial activation in healthy mice, not only in the lung but also in organs distal to the lung. To determine endothelial activa...

Ngày tải lên: 13/08/2014, 19:20

... via inhibiting the activation of L-TGF- Hydroxyproline content of rat lungsFigure 3 Hydroxyproline content of rat lungs. There was no sig- nificant difference in the hydroxyproline content of the ... could reduce hydroxyproline content in lung Hydroxyproline content is an important indicator of lung fibrosis. In this study, no significant differences in the hydroxyprolin...

Ngày tải lên: 12/08/2014, 14:20

... occur in any joint including the ankle, knee, hand, wrist, elbow, sacroiliac joint and other joints of the spine, however most commonly occurs in the lower extremity. In this case, although the ... as frequently as they have been in the past due to better con- trol of the disease. Competing interests The author(s) declare that they have no competing inter- ests. Author...

Ngày tải lên: 25/10/2012, 10:06

... mountains with woods in the South and floody plains in the North. The Po river runs through a fertile plain where world famous food and wines are produced. Green is undoubtedly one of the dominant ... wide. The mountains of the Appennine range divide Parma Province from Tuscany and from Ligury, and Po river flows through its territory. The territory of Parma Pr...

Ngày tải lên: 03/11/2012, 11:11

... it dissolves into the pulmonary lining and bind s to intra- cellular corticosteroid receptors. The re mainder of the drug that does not get absorbed into the lung (40-90%) is deposited into the mouth and ... the patient’s symptoms. Testing Several endocrine tests have been used for the screening and diagnosis of AS. The insulin-induced hypoglycemia test (IIHT) was once...

Ngày tải lên: 08/08/2014, 21:20

... immune responses and high serum levels of inflammatory cytokines [43]. In these infectious diseases, innate involvement promotes the secretion of IL-12 by macrophages and DCs and thereby creates a highly polarizing, ... response to infection. Nonetheless, these findings indicate that IL-27 is generated in response to various inflammatory stimuli and imply a role for this cytokin...

Ngày tải lên: 09/08/2014, 01:24

... nitrotyro- sine. Nitrotyrosine was present both within chondrocytes and in the cartilage matrix, and was seen mainly in the more superficial regions. The degree of immunostaining for nitro- tyrosine ... stress induces telomere instability and dysfunction in chondrocytes, subsequently resulting in cartilage ageing and the development of OA through a mechanism involving...

Ngày tải lên: 09/08/2014, 06:22

... backdrop the paper by Frey and colleagues represents only a minor blink of an eye in the vast Treg literature, but Frey and colleagues introduce a provocative ‘spin’ to their results as they question ... significantly different. Frey and colleagues also monitored the ‘homing’ of the CD4 + CD25 + Treg and detected an accumulation in the inflamed joints, thus excluding th...

Ngày tải lên: 09/08/2014, 06:23

... pattern of skin, renal and gastrointestinal pathology. The emergence of effective and conveniently administered therapy for PAH increases the importance of diagnosis and monitoring of this complication. ... is characterised by decreased production of the vasodilators nitric oxide and prostacyclin, and by enhanced release of endothelin-1. Endothelial cell dysfunction influenc...

Ngày tải lên: 09/08/2014, 06:23