Báo cáo y học: "Weakness in the ICU: a call to action" potx

... 7(2):94-100 â Ivyspring International Publisher. All rights reserved Research Paper Factors affecting the long-term response to tacrolimus in renal transplant patients: Pharmacokinetic and pharmacogenetic ... IP, et al. Genetic polymorphisms of the CYP3A4, CYP3A5, and MDR-1 genes and pharmacokinetics of the calcineurin inhibitors cyclosporine and tacr...

Ngày tải lên: 26/10/2012, 09:32

... estimate the extent of the acidic region responsible for cytochrome c docking. While no direct structural information is at hand for the docked complex, the interaction domain for cytochrome c on the ... denitrificans; cytochrome c oxidase; docking site; electron transfer; biphasic kinetics. Cytochrome c oxidase is the terminal complex of the...

Ngày tải lên: 22/02/2014, 07:20

... raises the possibility that any one or a combination of these properties may in uence the binding of apolipoproteins to lipoprotein particles. The capacity to fractionate lipid emulsions into relatively ... apolipoprotein E3 and E4 to emulsions (Eur. J. Biochem. 269) 5941 Differences in the binding capacity of human apolipoprotein E3 and...

Ngày tải lên: 08/03/2014, 09:20

... technology has been, theoretically, to increase the safety and com- pleteness of surgery in addition to increasing the confidence of the surgeon. This accounts for the increasing numbers of health ... state of the art in endoscopic sinus surgery includes many recent innovations. Prob- ably the most fundamental change in sinus surgery has been the adaptation of ri...

Ngày tải lên: 08/08/2014, 20:23

... modulating the immune function [42,43] might affect the initial steps in the inflammatory cascade and thus influence alterations in the functional activity of the major mediator of the inflammatory ... protein C3 is the initial point of the alternative pathway,and,atthesametime,aconvergepointofall three complement activation pathways, i.e. starting point for the term...

Ngày tải lên: 08/08/2014, 21:20

... the synovium, in ligaments especially near their insertions, in bone, in muscle, and in the outer third of the meniscus in the knee. In an unusual study in which the lead investigator became the study subject ... provided new insights into how OA may be successfully managed. The symptoms of osteoarthritis: pain and instability The pain of OA is activity-rel...

Ngày tải lên: 09/08/2014, 01:22

... consequence of the activation of many cell populations and, ultimately, of the upregulation of proinflammatory cyto- kines [19,20]. By whichever means they themselves become activated, they induce ... activity. The degree of disease activity at the start of a disease-modifying therapy is a major determinant of the disease activity attainable in treatment. Background...

Ngày tải lên: 09/08/2014, 01:22

... the definition of the Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) [21], the Bath Ankylosing Spondylitis Functional Index (BASFI), and the Bath Ankylosing Spondylitis Metrology ... and scientific understanding of the spondyloarthritides (SpA), which can be separated in predominantly axial and predominantly peripheral SpA. The clinical progress incl...

Ngày tải lên: 09/08/2014, 01:22

... proteins of apparently disparate function and cellular localisation. Pyrin is thought to interact with a variety of proteins within the cytoplasm and to play a key role in the modulation of inflammation ... characterised by fluctuating or irregularly recurring episodes of fever and systemic inflam- mation, affecting the skin, eyes, joints, and serosal surfaces. They in...

Ngày tải lên: 09/08/2014, 01:22

... memory, working memory, memory indexing/storage, relating expectancy to reality, and internal inhibition. Memory is recorded in several parts of the brain at same time as ‘memory molecules’ for ... to the reticular activating system via the reticular formation, beginning in the medulla and extend- ing to the midbrain. This pathway links the brain with perception of exter...

Ngày tải lên: 12/08/2014, 18:20

... on x-ray crystallographic data, NMR and in vitro assembly models, the importance of major homol- ogy region [10], the binding site for cyclophilin A (CypA) [11,12], and the CA dimer interfaces ... proper CA cone formation and mutations in CA are lethal when they inhibit CA assembly by destabilizing the intra and/ or inter molecular CA contacts, which ultimat...

Ngày tải lên: 13/08/2014, 09:20

Ngày tải lên: 13/08/2014, 11:22

... and induction of satiety [8-12]. The beauty of GLP-1 is that it does not stimulate Commentary Incretins in the ICU: is insulin on its way out? Michelle A Kovalaske and Gunjan Y Gandhi Division ... effects on insulin and glucagon in hospitalized patients. Finally, GLP-1 in and of itself may not cause hypoglycemia. When used in conjunction with insulin, however,...

Ngày tải lên: 13/08/2014, 16:21

... exercise capacity Commentary Weakness in the ICU: a call to action Robert D Stevens 1 , Nicholas Hart 2 , Bernard de Jonghe 3 and Tarek Sharshar 4 1 Departments of Anesthesiology and Critical Care ... indicate a paradigm shift to a proactive approach in managing neuromuscular complications in the ICU. In a recent issue of Critical Care, Gerovasili and colleagues [1...

Ngày tải lên: 13/08/2014, 19:20

... as there is a demonstrated mortality benefi t, but these patients should be able to safely receive prophylactic heparin. Competing interests The authors declare that they have no competing interests. Published: ... however, are not entirely conclusive. With further analysis, the authors showed that the increase in throm botic events only aff ected patients not receiving hepari...

Ngày tải lên: 14/08/2014, 07:21