Báo cáo y học: " Treatment of candidemia and invasive candidiasis in the intensive care unit: post hoc analysis of a randomized, controlled trial comparing micafungin and liposomal amphotericin " pot
Báo cáo y học: " Treatment of candidemia and invasive candidiasis in the intensive care unit: post hoc analysis of a randomized, controlled trial comparing micafungin and liposomal amphotericin " pot
... 5Research Treatment of candidemia and invasive candidiasis in the intensive care unit: post hoc analysis of a randomized, controlled trial comparing micafungin and liposomal amphotericin BBertrand ... following outcomes in patients treated for candidemia and invasive candidiasis: over-all treatment success; mycological response; and all-causemortality at day 8 and day 30 post treatment initiation. ... original work is properly cited.AbstractIntroduction Invasive candidiasis and candidemia are life-threatening nosocomial infections in intensive care patients.Methods A post hoc analysis of a...
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Báo cáo y học: "Cost of acute renal replacement therapy in the intensive care unit: results from The Beginning and Ending Supportive Therapy for the Kidney (BEST Kidney) Study" pps
... Italy, Israel, Portugal, and Spain; NorthAmerica: Canada, and the United States; South America:Brazil, an d Uruguay; Asia: China, Indonesia , Japan, and Singapore; and Australia.Cost analysis All ... may, at one time or another,be appropriate candidates for eithe r therapy, especiallywhen they are hemodynamically sta ble [5]. Results fromrandomized controlled trials and meta-analyses havefailed ... were asked to complete data entry and e-mail the data to the central office. On arrival, all data werescreened in detail by a dedicated intensive care specialistfor any missing information...
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Báo cáo y học: "Urinary cystatin C is diagnostic of acute kidney injury and sepsis, and predicts mortality in the intensive care unit" pptx
... revision of the draft for critical con-tent. CF participated in the design of the EARLYARF trial and in the statistical analysis of the data. ZE conceived the EARLYARF study and the concept of measuring ... and not normally distributed, median (interquartile range). AKI, acute kidney injury on admission to intensive care; uCysC, urinary cystatin C; uCr, urinary creatinine; pCysC, plasma cystatin ... exploration of the time course and reliability role of uCysC in the critically ill.Key Messages• In the ICU, urinary cystatin C is diagnostic of acutekidney injury.• In the ICU, urinary cystatin...
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Báo cáo khoa học: " Safety and efficacy of analgesia-based sedation with remifentanil versus standard hypnotic-based regimens in intensive care unit patients with brain injuries: a randomised, controlled trial [ISRCTN50308308]" pps
... bradycardia,cerebral infarction, oedema, hypotension and intracranialhaemorrhage in the remifentanil group, raised ICP in the fenta-nyl group, and bradycardia and raised ICP in the morphinegroup. ... additionalboluses and/ or increases in the infusion rate of propofol up to a maximum dose of 4 mg kg-1 h-1 to attain and then maintainoptimum analgesia and sedation. The remifentanil infusion ratewas increased ... MAP, HR, ICP and CPP were also recordedat the start of and at the time of adequate transitioning frompropofol to midazolam at the end of day 3 and if a patient wasextubated before day 5 of...
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Báo cáo y học: "Bench-to-bedside review: Leadership and conflict management in the intensive care unit" docx
... party might not be so important for the other party. In preparing for a negotiation try to understand what the otherparty wants. Identifying beforehand items that can easily begiven away and offering ... them away. A common mistake is to give a concession early. In that case, the other party will accept it and thereafter start the real negotiation. Taking more time, and making concessions smaller ... understanding and a possible starting pointfor improving skills, and further the development of organisation and communication.Competing interest The authors declare that they have no competing interests.References1....
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Báo cáo y học: "Bench-to-bedside review: Glucose and stress conditions in the intensive care unit" pot
... Bandyopadhyay A, Dandona P: Glucose intake induces an increase in activator protein 1 and early growth response 1 binding activities, in the expression of tissue factor and matrix metalloproteinase ... Aljada A, Friedman J, Ghanim H, Mohanty P, Hofmeyer D, Chaudhuri A, Dandona P: Glucose ingestion induces an increase in intranuclear nuclear factor kappaB, a fall in cellular inhibitor kappaB, ... adaptive. This acute hyperglycaemia participates in the maintenance of an adequate in ammatory response and consequently should not be treated aggressively. Hyperglycaemia induced by an exogenous...
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Báo cáo khoa học: "Elevated troponin and myocardial infarction in the intensive care unit: a prospective study" potx
... meta -analysis of randomized trials of antiplatelet therapy for prevention of death, myocardial infarction, and stroke in high-risk patients.BMJ 2002, 324:71-86.29. Assessment of the Safety and ... of results Analysis of troponin levels In accordance with the US National Academy of Clinical Bio-chemistry draft guidelines on biomarkers of the acute coronarysyndrome and heart failure, a ... Jesse RL, Warshaw MM, Valdes RJr: National Academy of Clinical Biochemistry Standards of Laboratory Practice: recommendations for the use of cardiacmarkers in coronary artery diseases. Clin Chem...
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Báo cáo y học: "Bench-to-bedside review: Candida infections in the intensive care unit" ppsx
... membranes with Candida and alteration of natural host barriers (wounds, surgery, and insertion of indwelling intravascular and urinary catheters). The gastrointestinal tract, the skin and the ... was lower in the combination treatment arm.Until clinical trials are reported that demonstrate efficacy and safety, the indiscriminate use of combination therapy in patients with invasive candidiasis ... than liposomal amphotericin B (3 mg/kg per day) for first-linetherapy of candidaemia or invasive candidiasis [34]. In a randomized, double-blind study conducted in patients with invasive candidiasis...
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Báo cáo y học: "Bench-to-bedside review: Mobilizing patients in the intensive care unit – from pathophysiology to clinical trials" pot
... understanding of the pathophysiology of ICU-acquired weakness and the potential role of early mobility in the ICU, including its safety, feasibility, and clinical benefit, isat a relatively early ... immobility can leadto a pro-inflammatory state caused by increased systemicinflammation via increases in pro-inflammatory cytokines[30,31]. Long-term immobility may result in increased levels of ... animportant role in muscle preservation and protection.Physical therapy in the intensive care unitPhysical therapy practices vary greatly across ICUs, rangingfrom passive range of motion to transferring...
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Báo cáo y học: "Endothelial Circulating soluble urokinase plasminogen activator receptor is stably elevated during the first week of treatment in the intensive care unit and predicts mortality in critically ill patients" potx
... prospectively upon admissionto the medical intensive care unit (ICU), on Day 3 and Day 7, and compared to 43 healthy controls. Clinical data,various laboratory parameters as well as investigational inflammatory ... suPAR and classic clinicalinflammatory parameter in an intensive care environ-ment we performed ROC analyses. The obtained AUC of suPAR for predicting sepsis in critically ill patients atadmission ... between Day 4 and Day 7. On the other hand, n = 3 died during the first 24hours, n = 18 at days 2 and 3, and n = 16 between Day 4 and Day 7. For patients that were treated at the ICU for atleast...
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