Báo cáo y học: "Bench-to-bedside review: β-Adrenergic modulation in sepsis" pps

... postulated that cytokine synergy plays a key role in septic myocardial depression. When con- sidering IL-1β and TNF-α independently, substantially higher concentrations of each cytokine are required ... bio- chemical pathway than the early depression, and may involve de novo protein synthesis. The generation of NO may be central to both early and late depression of myocytes in in vitro an...

Ngày tải lên: 12/08/2014, 19:21

... generated by the coagulation process, the fibrinolytic system degrades fibrin by its key enzyme, plasmin. Plasmin formation from plasminogen is mainly activated by tissue plasminogen activator and inhibited ... G s proteins and increased inhibitory activity of G i proteins [38]. The sustained adrenergic stimulation per se may trigger cyto- kine production by cardiomyocytes [39]. From another...

Ngày tải lên: 13/08/2014, 18:22

... reporting barriers partly owing to fewer liability concerns, and an opportunity to study recovery patterns [75]. Ideally, error reporting should be voluntary, anonymous, centralized to increase ... The technology permits clinicians to enter orders directly into a computer workstation that is linked to a hospital clinical infor- mation system [47]. The main advantages of these systems are that...

Ngày tải lên: 25/10/2012, 10:35

... +250 GG genotype, again suggesting that polymorphisms may be ‘good’ or ‘bad’, depending on the outcome of interest. Interleukin-1 αα and interleukin-1 ββ IL-1, a potent proinflammatory cytokine released ... transition in the first intron of LT-α, has been identified as a potentially influential locus in many inflammatory conditions. This polymorphism is part of a complex haplotype includi...

Ngày tải lên: 12/08/2014, 19:22

... with increasing physician experience. Carlucci and coworkers [9] reported an 8-year retrospective study in which they investigated the changes in clinical practice of NIV in COPD patients. In that ... surgery No active gastrointestinal bleeding No impairment in swallowing Hemodynamic and rhythm stability Adequate fitting of the interface 102 A multicenter randomized controlled trial...

Ngày tải lên: 12/08/2014, 20:20

... while maintaining infection control measures), and serve as a way to train treatment teams at different hospital sites. Indeed, internet-based technology proved invaluable during the SARS outbreak in ... placed in quarantine after exposure, some of them falling ill, becoming critically ill and even succumbing to SARS. Staff morale was addressed in some institutions by encouraging and co...

Ngày tải lên: 12/08/2014, 20:21

... examining the full effects of sleep inter- ventions over multiple days, identifying appropriate endpoints and in a relatively large number of patients. Polysomnography is currently the definitive ... more interventions. In clinical practice, they offer the only real means of assessing the efficacy of interventions in attempting to improve individual patients’ sleep. Patient assessment U...

Ngày tải lên: 13/08/2014, 08:20

... it maintains airway patency and prevents pulmonary infection. However, tracheal suctioning induces mucosal injury, exposing the basement membrane and thereby facilitating bacterial adhesion in ... maintain airway hygiene independently and remain symptomatic after 24 hours of aggressive chest physiotherapy (every 4 hours). Clinical experience indicates that atelectasis recurs frequently afte...

Ngày tải lên: 13/08/2014, 08:21

... critical care may be poorly organized, with ICUs usually being ad hoc areas within hospitals [17]. Specialty trained intensivists are rare. Physi- cians and nurses are in short supply and underpaid ... health care, including vaccination and nutrition, is not ‘critical care’. However, in many hospital wards of developing countries, the majority of patients dying of AIDS, complicating infec...

Ngày tải lên: 13/08/2014, 11:22

... compared to MODS in patients with brain injury [46]. Severity assessment based on nursing workload use The Therapeutic Intervention Scoring System (TISS) TISS was originally developed in 1974 to assess ... Metnitz P: The changing prognostic determinants in the critically ill patient. In 2007 Yearbook of Intensive care and Emergency Medicine. Edited by Vincent JL. Heidelberg: Spring...

Ngày tải lên: 13/08/2014, 20:21