Báo cáo y học: "Macrophage migration inhibitory factor, infection, the brain, and corticosteroids" ppsx

... which injury is caused, in part, by the causative organism and, in part, by the host’s own inflammatory response. Macrophage migration inhibitory factor (MIF) is a pro-inflammatory cytokine and a ... medical Commentary Macrophage migration inhibitory factor, infection, the brain, and corticosteroids Madelijn Geldhoff, Barry B Mook-Kanamori and Diederik van de Beek D...

Ngày tải lên: 13/08/2014, 18:22

... analyzed in the synovial lining cells (fibroblast-like and macrophage-like synoviocytes), sub- synovial nonlymphoid mononuclear cells (monocytes, macro- phages, and mast cells), and on endothelial ... gene-deficient and wild-type mice with zymosan. The synovial inflammation medi- ated by zymosan is biphasic, with an initial peak at day 1, fol- lowed by a continuous decrease, and...

Ngày tải lên: 09/08/2014, 08:22

... Kim and KW Kim designed and performed all experiments and drafted the manuscript. HG Jung, HJ Oh and KS Yoon assisted in designing the study. ML Cho and SH Lee conceived the study and drafted and ... pathways. Endocrinology 2009, 150:3128-3137. 10. Sampey AV, Hall PH, Mitchell RA, Metz CN, Morand EF: Regulation of synoviocyte phospholipase A2 and cyclooxygenase 2 by macr...

Ngày tải lên: 12/08/2014, 15:22

... Larson and Horak immunity, namely activation of CD8 + lymphocyte and macro- phage functions. The Th2 cytokines generally support the humoral mediated responses related to B-lymphocyte function and ... during cardiopulmonary bypass, which may directly induce MIF secretion by immune cells [6]. MIF thereby stimulates Th1 immune activity and induces proinflammatory cytokines and amp...

Ngày tải lên: 12/08/2014, 23:23

... therapy was changed in based on the susceptibility profile of the path- ogen. The duration of antibiotic therapy was usually 7 to 10 days. The third group included patients with lymphocytic meningitis (pleocytosis ... T, Calandra T: Macrophage migration inhibitory factor: gene polymorphisms and susceptibility to inflamma- tory diseases. Clin Infect Dis 2005, 41:S513-S519. 3. Cal...

Ngày tải lên: 13/08/2014, 16:21

... selectivity concerning the size of the ion. Thus, the affinity of the different metal ions in MTs is governed primarily by the thermody- namic stability of the thiolate–metal bond. Therefore, soft metals ... explore the isostuctural replacement of Zn(II) with Cd(II), by monitoring the peptide structure and the flexibility of Zn(II) and Cd(II) by NMR spectroscopy. Another i...

Ngày tải lên: 16/02/2014, 15:20

... analysis and participated in the study design and drafting of the manuscript. FL and JS participated in the study design and drafting of the manuscript. TL and NB performed immunocytochemistry ... analysis of salivary epithelial cells. Cells were obtained from minor salivary glands (a–e) and the HSG cell line (f–i). Positive staining for cytokeratin 7 (a) and cytokera...

Ngày tải lên: 09/08/2014, 07:20

... contributed by designing the experi- ments, by analysing and interpreting the results, by writing of the manuscript, and by arranging the grant support for this study. Acknowledgements We thank Swamy Polumuri, ... TTS, and hypoxanthine-guanine phosphoribosyl transferase (HPRT) were designed using the Primer Express 2.0 program (Applied Biosystems) and were synthesised at th...

Ngày tải lên: 09/08/2014, 10:23

... early and late stages of the disease. We further hypothesised that the role of VEGF in the lung may be as an epithelial mitogen integral to lung repair. We have explored this hypothesis and additionally ... cell-associated[14]. It is the pre- dominant isoform and most biologically active in the physiological state[15]. Recovery from lung injury/ARDS requires functional/ physic...

Ngày tải lên: 12/08/2014, 14:20

... opportunity, yet this rep- resents the one area beyond the standard curriculum where further training can be gained and is therefore the only way in which current chiropractors may finally gain new ... process involved examining themes for commonal- ity, classifying them for uniformity, and then reaching agreement on the final list of six key themes. Once the themes were set an...

Ngày tải lên: 25/10/2012, 10:06