Báo cáo y học: "Cell death in sepsis: a matter of how, when, and where" potx

... exacerbate liver injury [9]. In addition to apoptosis, certain caspases, such as caspase-1, are involved in cytokine maturation by proteolytically proces- sing the inactive precursors of interleukin ... not apoptotic cells, is systemically elevated in human sepsis and functions as a mediator of endotoxin lethality in mice [12]. Intense research has recently delineated the sign...

Ngày tải lên: 13/08/2014, 18:22

... for citation purposes) present. Inter-rater clinician agreement for cough qualities of dry/wet and brassy/non brassy was good. Accuracy and reliability of symptoms are important in clinical and ... dry cough as determined by clinicians and parents has good clinical validity as it has good agreement with, and relates to, quantification of airway secretions. However as mini- m...

Ngày tải lên: 12/08/2014, 18:21

... in- terests since they are not always available. 770 age and gender. In International AAAI Confer- ence on Weblogs and Social Media. Mark Hall, Eibe Frank, Geoffrey Holmes, Bernhard Pfahringer, Peter ... Kumar, Jasmine Novak, Prabhakar Raghavan, and Andrew Tomkins. 2004. Structure and evolu- tion of blogspace. Commun. ACM, 47:35–39, De- cember. Amanda Lenhart, Kristen Purcell, Aa...

Ngày tải lên: 07/03/2014, 22:20

... coverage RNA-Seq in the same individual. This comparison allowed us to directly evaluate the sensitivity and specificity of RNA- Seq in identifying coding variants, and to evaluate how key parameters ... Ensembl's transcript library are hypothetical and not confirmed to be expressed. A list of core exons as defined by the Affymetrix (Santa Clara, California, USA) Human E...

Ngày tải lên: 09/08/2014, 20:22

... key mediators of apoptosis are caspases, leading to the caspase-dependent pathway of apoptotic cell death. Cas- pases are intracellular cysteine proteases that cleave various substrates including ... cell death involves measuring intracellu- lar components (eg, in the liver, alanine and aspartate ami- notransferases; in the heart, creatine kinase and troponin T), which are rele...

Ngày tải lên: 13/08/2014, 16:21

... existing evidence of an involvement of TLRs in the pathogenesis of RA and other inflammatory diseases, a great deal of interest exists in understanding the molecular basis of the signalling pathways ... macrophages may have altered signalling patterns when compared to other cell types, and IL-10 may have both anti- and pro-inflammatory functions in RA. In macrophages...

Ngày tải lên: 09/08/2014, 10:23

... characterized' paraneoplastic antibodies. b) CSF analysis assists in making the diagnosis of PLE by detecting inflammatory abnormalities (lymphocytic pleo- cytosis, elevated proteins, intrathecal ... brain magnetic resonance imaging findings and the results of the brain biopsy, we concluded that our patient had a 'definite' diagnosis of paraneoplastic limbic encepha...

Ngày tải lên: 11/08/2014, 21:22

Ngày tải lên: 12/08/2014, 18:21

... dosing of potential new therapies. Altering the intrinsic balance of coagulation and inflammation: detrimental consequences A safe assumption is that any new therapies that alter the intrinsic ... or synthetic analogues of coagulation cascade components (e.g. protein C, thrombin, and factor VIIa or Xa), coagulation inhibitors (e.g. heparin or analogues), or agonists or antagonists...

Ngày tải lên: 12/08/2014, 19:21

... for early risk stratification and prediction of inhospital and overall morbidity and mortality in a range of conditions including stroke [6], myocardial infarction [11], cancer [8] and trauma [12]. ... local research/ethics commit- tee as this was an observational study looking at plasma DNA, a new variable measured from blood samples that were taken as part of standard cl...

Ngày tải lên: 12/08/2014, 23:23