... began (day 0), at the end of each 5 day cycle of DSSadministration (day 5, 26, and 47, and after 16 days of recovery prior to beginning the next DSS cycle (days 21,42, and 63). Freshly obtained ... Ishikawa T, Nakagawa S, Yamaguchi T,Yoshida N, Minami M, Kita M, Imanishi J, Yoshikawa T: Enhancedintestinal inflammation induced by dextran sulfate sodium in tumor necrosis factor-alpha deficient ... of edema, acute inflammatory infiltrates, and focal ulceration. Chronic colitis generated by 3 cycles of 5 days of 3% DSS in drinking water, followed by 16 days of plain water resulted in development...