... something like a guinea pig": information and assent of legal minors in clinical trials – assessment of understanding, appreciation and reasoning Michael Koelch*, Hanneke Singer, Anja Prestel, ... feasibility of providing information about clinical tri- als according to informed consent criteria and the under- standing of information re...
Ngày tải lên: 13/08/2014, 18:21
... Evaluation Criteria for Solid Tumors (RECIST) for palpable measurable disease. Key exclusion criteria included inflammatory breast cancer, clinically sig- nificant cardiac disease, and inadequate ... the clinical benefit of docetaxel plus cape- citabine in patients with breast cancer [23]. In a randomized trial in patients with MBC, the combination of capecitabine 1250 m...
Ngày tải lên: 08/08/2014, 17:20
Báo cáo y học: "Administering the MADRS by telephone or face-to-face: a validity study" docx
... prelimi- nary results showed that only very little variance was due to interviewer variation, indicating that the reliability of the interviewers was high. Third and finally, the in- person interview ... administra- tion may have several advantages. It (a) can include all original items, (b) preserves the characteristic of a clinical interview, and (c) is less costly and time-c...
Ngày tải lên: 08/08/2014, 21:20
Báo cáo y học: "Peripheral blood but not synovial fluid natural killer T cells are biased towards a Th1-like phenotype in rheumatoid arthritis" pptx
... manuscript. MT participated in frequency analysis of NKT cells. KB partici- pated in reactivity assays. PG provided clinical material. VS and JR critically revised the manuscript. PS coordinated ... 1998, 188:1521-1528. 6. Nieda M, Nicol A, Koezuka Y, Kikuchi A, Takahashi T, Nakamura H, Furukawa H, Yabe T, Ishikawa Y, Tadokoro K, et al.: Activation of human Valpha24NKT cells b...
Ngày tải lên: 09/08/2014, 06:22
Báo cáo y học: "Rheumatoid arthritis is an independent risk factor for multi-vessel coronary artery disease: a case control study" pdf
... USA 2 Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN, USA 3 Mayo Alliance for Clinical Trials and the Mayo Clinic, Rochester, MN, USA 4 Division of Biostatistics, Mayo Clinic, ... scleritis. Use of corticosteroids and disease modifying therapy was fairly typi- cal of patients with long-standing RA. Coronary artery involvement There was a statistically signif...
Ngày tải lên: 09/08/2014, 06:23
Báo cáo y học: "Prolonged, granulocyte–macrophage colony-stimulating factor-dependent, neutrophil survival following rheumatoid synovial fibroblast activation by IL-17 and TNFalpha" doc
... colony-stimulating factor, CCL2 and CXCL8 – failed to inhibit neutrophil survival any further. Using an inhibitor of the phosphatidylinositol-3-kinase signal- ling pathway (Ly294002) and an inhibitor ... patterns in inflammatory arthritis. Proc Natl Acad Sci USA 1994, 91:8562-8566. 3. Morita Y, Yamamura M, Kawashima M, Harada S, Tsuji K, Shibuya K, Maruyama K, Makino H: Flow cyto...
Ngày tải lên: 09/08/2014, 10:23
Báo cáo y học: "Failure to respond to endogenous or exogenous melatonin may cause " pdf
... Relative humidity was 4 0–6 5%, and temperature was maintained at 23 ± 3°C. Due to bright light's ability to cause retinal damage to albino rats, light intensity was maintained between 100 and ... ganglion in the spinal cord, and eventually to the pineal gland, which releases the indoleamine hormone melatonin [5]. Pinealoctyes within the pineal gland convert tryptophan into 5-h...
Ngày tải lên: 10/08/2014, 09:20
Báo cáo y học: "Surgical treatment for pulmonary metastases from esophageal carcinoma after definitive chemoradiotherapy: Experience from a single institution" doc
... esophageal carcinoma to eluci- date its efficacy. A previous report indicated that solitary pulmonary metastasis from esophageal carcinoma was a favorable indicator for surgical treatment [6]. In ... Kawamura M, Sato T, Nakagawa K, Nakajima J, Yoshino I, Ikeda N, Horio H, Akiyama H, Kobayashi K: Disease-free interval length correlates to prognosis of patients who underwent metastasec...
Ngày tải lên: 10/08/2014, 09:22
Báo cáo y học: "Effective cardiac resynchronization therapy for an adolescent patient with dilated cardiomyopathy seven years after mitral valve replacement and septal anterior ventricular exclusio" ppsx
... and a pediatric cardiologist in charge in a pediatric ward of Kyoto university hospital. SB is an assistant professor and a pediatric cardiologist in charge in a pediatric ward of Kyoto university ... an attending physician in the pediatric outpa- tient clinic in Kyoto university hospital. TD is an attending physician in the car- diovascular outpatient clinic in...
Ngày tải lên: 10/08/2014, 09:22
Báo cáo y học: "Heart echinococcus cyst as an incidental finding: early detection might be life-savin" doc
... Echinococcusgranulosusinfectionin humans. Cardiac involvement is rare, and early diagnosis and prompt surgical interventio n are critical, with com- plete resection of the germinal layer being of major importance for ... 60%, without regional wall motion abnormalities. Coronary angiography revealed normal coronary arteries. Excision of the cardiac cyst was planned by using cardi- op...
Ngày tải lên: 10/08/2014, 09:23