... studying the properties of these receptors to determine the level of conservation of their function and their role in the complex development of this parasite. One of these, SmRXR, has been the ... of protein synthesis characteristic of these stages. Interest- ingly, the levels of detected protein vary considerably throughout the life cycle, in a manner different...
Ngày tải lên: 23/03/2014, 21:20
... poly-L-lysine-coupled lysozyme. Poly-L- lysine-coupled lysozyme is highly cationic and sufficiently large to be retained in the joint for prolonged periods of time. Both association with synovial ... serum levels of IL-1 and developed severe polyarthritis by 4 weeks of age. Hyperplasia of the synovial lining, pannus formation and, ultimately, cartilage destruction were e...
Ngày tải lên: 09/08/2014, 14:22
Báo cáo y học: "A vertebrate case study of the quality of assemblies derived from next-generation sequence" doc
... found 16.3% of the novel sequences from the Illumina/SOAP assembly and 9.0% from the 454/Newbler assembly matched cDNA/mRNA sequenc es. Approxim atel y 41. 6% of the novel sequences from the 454/Newbler ... Seque ncing cost of NGS assemblies compared to the reference assembly. The coverage of raw bases for the reference assembly is 6.6-fold, for the 454...
Ngày tải lên: 09/08/2014, 22:24
Báo cáo y học: "A prospective observational study of the relationship of critical illness associated hyperglycaemia in medical ICU patients and subsequent development of type 2 diabetes"
... M: The impact of the severity of sepsis on the risk of hypoglycaemia and glycaemic variability. Crit Care 2008, 12:R129. 40. Rattanataweeboon P, Vilaichone W, Vannasaeng S: Stress hyperglycemia ... 0.05. The study was approved by the Ethics Committee of the University Hospital Centre. All patients included in the study signed an informed consent form. The study was...
Ngày tải lên: 25/10/2012, 10:02
Báo cáo Y học: Diffusion through channel derivatives of the Escherichia coli FhuA transport protein doc
... probably through rapid opening and closing of the FhuAD5–160 channel or, less likely, rapid membrane entry and exit of the protein. The instability of the channels formed by FhuAD5–160 may have ... [6]. Removal of the globular domain may increase the flexibility of loop 4 and other surface exposed loops so that rapidly moving loops may cause the frequent transitio...
Ngày tải lên: 31/03/2014, 08:20
Báo cáo y học: "Urokinase, a constitutive component of the inflamed synovial fluid, induces arthritis" pps
... by infiltration of CD4 – Mac-1 + mononuclear cells, by the formation of pannus and by occasional cartilage destruction. The absence of monocytes and lymphocytes diminished the frequency of synovitis ... to hypertrophy and inflamma- tory cell infiltration of the synovia, to pannus formation and to the development of bone erosions was performed on the fourth day...
Ngày tải lên: 09/08/2014, 01:21
Báo cáo y học: "First-dose analgesic effect of the cyclo-oxygenase-2 selective inhibitor lumiracoxib in osteoarthritis of the knee: a randomized, double-blind, placebo-controlled comparison with celecoxib [NCT00267215]" doc
... immediately before and at 3 and 5 hours after the first dose of study medication. The primary efficacy variable was pain intensity difference (PID) between the baseline pain assessment and the mean of ... phase The three main hypotheses of the primary efficacy variable (APID between the baseline pain assessment and the mean of the 3-hour and 5-hour actual p...
Ngày tải lên: 09/08/2014, 07:20
Báo cáo y học: "B cell-activating factor of the tumor necrosis factor family (BAFF) is expressed under stimulation by interferon in salivary gland epithelial cells in primary Sjögren''''s syndrome" ppt
... drafting of the manuscript. TL and NB performed immunocytochemistry experiments. CL performed the biop- sies of minor salivary glands. XM conceived of the study and its design and edited the manuscript. ... the study design and drafting of the manuscript. JEG performed statistical analysis and participated in the study design and drafting of the manuscrip...
Ngày tải lên: 09/08/2014, 07:20
Báo cáo y học: " Runaway repeats force expansion of the Phytophthora infestans genom" ppt
... whereby regions of low repeat content and high gene density with conserved synteny (the ‘core genome’) are interrupted by repeat-rich regions of low gene density where synteny has broken down (the ... misunderstood. The application of molecular and DNA sequencing analyses has altered our view of oomycetes and provided new insight into the evolution of these organism...
Ngày tải lên: 09/08/2014, 20:20