Báo cáo y học: " In vitro activities of novel 4-HPR derivatives on a panel of rhabdoid and other tumor cell lines" docx

... combined chemotherapy and radiotherapy. Radioactive derivatives can also be used to evaluate bioavailability of 4-HPR in vivo, using non-invasive imaging. In addition, the peptidomimetic derivatives ... display significant potency in all RT cell lines tested. Since iodo conjugation can potentially be used to deliver radiotherapy and taken advantage of for radiation-...

Ngày tải lên: 13/08/2014, 18:21

... eradication therapy and the efficacy of chemotherapy. Microbiol Immunol, 1997. 41: 7-12. 14. Gotoh A. , Kawakami Y. , Akamatsu T., and Katsuyama T. Interaction of drugs for eradication therapy ... Pseudomonas aeruginosa, and three strains of Klebsiella pneumoniae and two strains of Klebsiella oxytoca were also investigated for the antibacterial evaluation study. They w...

Ngày tải lên: 31/10/2012, 17:03

... results in the intracellular accumulation and storage of the unprocessed glycosami- noglycans (GAG), dermatan sulfate and heparan sulfate. Patients with MPS I show variable clinical phenotypes, ... generation lentiviral vector was used to deliver arylsulfatase A cDNA into the brain of metachromatic leukodystrophy mice [21] and b-glucuronidase cDNA into the brain of mucopolysac...

Ngày tải lên: 24/03/2014, 04:21

... lincomycin, pristinamycin, vanco- mycin, teicoplanin, ciprofloxacin, tetracycline, minocycline, trimethoprim-sulfamethoxazole, rifampicin, fusidic acid, gentamicin, kanamycin, tobramy- cin, chloramphenicol ... and Antoine Talarmin* Address: Institut Pasteur de Madagascar, BP 1274, Antananarivo 101, Madagascar Email: Frédérique Randrianirina - frederique@pasteur.mg; Jean-Louis Soares - soar...

Ngày tải lên: 08/08/2014, 19:20

... 5'- GCCAAGAGAATATCCG AACT-3' 5'- AGGCACAGTGGAACAA GGACTTGT-3' [GenBank: NM_000584 ] 60°C 78°C Bovine MMP-1 5'- CAAGAGCAGATGTGGA CCAA-3' 5'- CTGGTTGAAAAGCATG AGCA-3' [GenBank: ... establish a standardised in vitro model of RA-related early cartilage destruction with native, intact cartilage in order to analyse the matrix-degrading capacity of...

Ngày tải lên: 09/08/2014, 01:22

... effect of drugs on PAF-AH activity was evaluated in rabbit plasma. The in vitro enzymatic assay of plasma PAF-AH was perfo rmed in the presence of several con- centrations of each drug in the assay ... 8:17 http://www.journal-inflammation.com/content/8/1/17 Page 8 of 11 RESEARCH Open Access In vitro anti-inflammatory and anti-coagulant effects of antibiotics towa...

Ngày tải lên: 11/08/2014, 03:20

... effect of drugs on PAF-AH activity was evaluated in rabbit plasma. The in vitro enzymatic assay of plasma PAF-AH was perfo rmed in the presence of several con- centrations of each drug in the assay ... enzymes in a concentration depended man- ner (Figures 1 and 2), while only clarithromycin and azi- thromycin induced an in vitro increase of rabbit plasma PAF-...

Ngày tải lên: 11/08/2014, 06:23

... 22.6 Cordia dichotoma Boraginaceae Clammy cherry, lasoori, gunda, Anti-inflammatory Leaves 14.1 Colocasia esculenta Araceae Kachalu, Arvi Anti-diarrhea, anorexia, antipyretic. Leaves 21.5 Momordica charantia Cucurbitaceae ... Morishima C, Shuhart MC, Wang CC, Liu Y, Lee DY: Inhibition of T -cell inflammatory cytokines, hepatocyte NF-kappaB signaling, and HCV infection by standardized Si...

Ngày tải lên: 11/08/2014, 21:21

... implications, including the important application as chemo therapeutic and/ or prophylactic agents of viral diseases of humans, lower animals and marine animals, particularly in aquaculture and conservation ... and extracts. YL was the principle investigator of this project and designed and conceived of the study, and participated in its coordination, and data analy...

Ngày tải lên: 12/08/2014, 04:20

... purposes) Discussion Several pharmacokinetic and pharmacodynamic parame- ters, including bioavailability, receptor binding-affinity, and elimination half-life contribute to the safety and effi- cacy profile of ... Female Race Hispanic Caucasian Caucasian Cause of death Cerebrovascular Cerebrovascular Cerebrovascular Medical history Healthy Healthy Healthy Medications None None None...

Ngày tải lên: 12/08/2014, 15:21