Handbook of Pediatric Cardiovascular Drugs - part 8 pdf

... sterile packaging. Propofol is an isotonic emulsion with a pH of 7 to 8. 5 and a pKa of 11. Propofol injectable emulsion is available in ready to use 20-mL, 50-mL, and 100-mL infusion vials containing ... short context-sensitive half-time of propofol, even with prolonged periods of infusion, makes it the drug of choice for producing I.V. “conscious sedation” as a part of ba...

Ngày tải lên: 13/08/2014, 17:22

... concentrations four- to seven-fold higher than healthy patients after a single dose Pharmacokinetics Carvedilol has an onset of action of α-blockade within 30 minutes and of β-blockade of within 1 ... Fail 9(2): 100–105. 6. Materson, B. (1 983 ). “Insights into intrarenal sites and mechanisms of action of diu- retic agents.” Am Heart J 106(1 Pt 2): 188 –2 08. 7. Ritland, J.,...

Ngày tải lên: 13/08/2014, 17:22

... incidence of serious drug-drug interac- tions in pediatric patients receiving chronic antiepilepsy drugs. 12 Implications of CYP-450 Drug-Drug Interactions of Cardiovascular Drugs The CYP-450 system ... effects. 1 Protein-Binding Effects Drugs in plasma bind to proteins, including albumin, -1 -acid- glycoprotein ( -1 -AG), and lipoproteins. Albumin is the major serum prot...

Ngày tải lên: 13/08/2014, 17:22

... the age HR - Fluid restriction - Diuretics - Venous vasodilators - Arrhuthmia? - Rule out {{ JET }} - Anti-arrthythimic druge - Pacemaler - Cardioversion Preload Figure 3-4 . Treatment of acute ... inhibitors: - Milrinone - lnamrinone Inotropic drugs: - Dopamine - Dobutamine Epinephrine inodilator Norepinephrine (Echolcardiography) CaCI 2...

Ngày tải lên: 13/08/2014, 17:22

... onset of action of approximately 1 hour and a duration of action of 12 to 24 hours. Oral absorption of the drug is dependent on the prepa- ration used, and protein binding is 95%. The half-life ... binding of the drug ranges from 91 to 98% , with hepatic metabolism to multiple metabolites, including the active agent, canrenone. The half-life of spironolactone is 78 to 84 mi...

Ngày tải lên: 13/08/2014, 17:22

... to long-term maintenance doses of 0.05 to 0.15 mg/kg/day. Some centers continue low-dose Table 8- 1 . Potential combinations of immunosuppressive drugs used in pediatric thoracic transplan- tation a Number ... in acquired or congeni- tal long QT syndrome 38 and to treat and prevent ventricular tachyarrhythmias, particularly in the postoperative course of cardiac disease. 8....

Ngày tải lên: 13/08/2014, 17:22

... inactivation. Circulation 1993; 88 : 288 4– 288 7. 61. Hallman M, Bry K, Lappalainen U. A mechanism of nitric oxide-induced surfactant dysfunction. J Appl Physiol 1996; 80 :2035–2043. 62. Semigran MJ, ... Journal of Medicine 2002; 347(5):322–329. 81 . Max M, Rossaint R. Inhaled prostacyclin in the treatment of pulmonary hypertension. European Journal of Pediatrics 1999; 1 58: S2...

Ngày tải lên: 13/08/2014, 17:22

... Diluents Dexmedetomidine hydrochloride is the S-enantiomer of medetomidine and is chemically described as (+ )-4 -( S )-[ 1-( 2, 3-dimethylphenyl) ethyl ]-1 H- imidazole monohydrochloride. The active ingredient ... depres- sion because of its nonopioid mechanism of analgesia. Dexmedetomidine has a 1600-fold greater affinity for the α2-receptor compared with α1-receptors. 33...

Ngày tải lên: 13/08/2014, 17:22

... 78 81 enalapril, 78, 81 84 lisinopril, 78, 85 88 adrenoceptor antagonists, 78, 107–112 phenoxybenzamine, 78, 107–109 phentolamine, 78, 110–112 angiotensin II receptor blockers, losartan, 78, 88 –91 calcium ... and, 40 etomidate, 284 – 288 fentanyl, 303–306 halothane/isoflurane/sevoflurane/ desflurane, 310–314 ketamine, 289 –294 metaraminol and, 61 midazolam, 307–310 propofol, 280 – 28...

Ngày tải lên: 13/08/2014, 17:22

... RECIPES IN C: THE ART OF SCIENTIFIC COMPUTING (ISBN 0-5 2 1-4 310 8- 5 ) Copyright (C) 1 98 8- 1 992 by Cambridge University Press.Programs Copyright (C) 1 98 8- 1 992 by Numerical Recipes Software. Permission ... difficult. 7 48 Chapter 16. Integration of Ordinary Differential Equations Sample page from NUMERICAL RECIPES IN C: THE ART OF SCIENTIFIC COMPUTING (ISBN 0-5 2 1...

Ngày tải lên: 24/12/2013, 12:16