Handbook of Pediatric Cardiovascular Drugs - part 2 ppt
Handbook of Pediatric Cardiovascular Drugs - part 2 ppt
... inhibitors:
- Milrinone
- lnamrinone
Inotropic drugs:
- Dopamine
- Dobutamine
Epinephrine
inodilator
Norepinephrine
(Echolcardiography)
CaCI
2
-Levosimendan, tri-iodo-
thyronine
- Mechanical support
- ... Atropine
- Isoprenaline
Optimal
Normal
for the age
HR
- Fluid restriction
- Diuretics
- Venous
vasodilators
- Arrhuthmia?
- Rule out {{ J...
Handbook of Pediatric Cardiovascular Drugs - part 1 docx
... incidence of serious drug-drug interac-
tions in pediatric patients receiving chronic antiepilepsy drugs.
12
Implications of CYP-450 Drug-Drug Interactions of Cardiovascular Drugs
The CYP-450 system ... 87%
a
Hgb = 14 .2 g/dL, VO
2
= 62 mL/min, BSA = 0.3 m
2
Qp
i
= 2. 97 L/min/m
2
Qs
i
= 4.43 L/min/m
2
Qp:Qs = 2. 97 / 4.43 = 0.67:1
PVR = TPG / Qp
i
= (16 − 11 mm...
Handbook of Pediatric Cardiovascular Drugs - part 4 ppsx
... 5 to 20 mg/dose every 24 hours
Hypertension: 2. 5 to 5 mg/dose every 24 hours
Pharmacokinetics
Metolazone has an onset of action of approximately 1 hour and a duration of
action of 12 to 24 hours. ... onset of action of 2 hours after oral administration and
a duration of action of 6 to 12 hours. The duration of action is approximately 2
hours after I.V. injecti...
Handbook of Pediatric Cardiovascular Drugs - part 5 pdf
... concentrations four- to seven-fold higher than healthy patients after
a single dose
Pharmacokinetics
Carvedilol has an onset of action of α-blockade within 30 minutes and of
β-blockade of within 1 ... days to
300 mg every 8 hours
Extended release: 22 5 mg every 12 hours; increase every 5 days to
325 mg every 12 hours, to a maximum of 425 every 12 hours
Pharmacokinetics Pro...
Handbook of Pediatric Cardiovascular Drugs - part 6 docx
... after I.V. doses of 1 .25 to 1.5 mg/kg,
with an average concentration of 22 µg/mL. Peak levels increase to an average of
87 µg/mL after 7 to 10 days of continuous dosing. Serum half-life after the ... mL/min, admin-
ister 25 % of normal dose or use alternative agent
Pharmacokinetics
The onset of action of bretylium is 6 to 20 minutes, with a peak effect at 6 to
9 hours. Th...
Handbook of Pediatric Cardiovascular Drugs - part 7 pot
... Journal of Medicine 20 02;
347(5): 322 – 329 .
81. Max M, Rossaint R. Inhaled prostacyclin in the treatment of pulmonary hypertension.
European Journal of Pediatrics 1999; 158:S23–S26.
82. Hoeper ... Three-year results of a randomized, dou-
ble-blind, controlled trial of mycophenolate mofetil versus azathioprine in cardiac
transplant recipients. J Heart Lung Transplant 20 05;...
Handbook of Pediatric Cardiovascular Drugs - part 8 pdf
... area at most 1.16 m
2
:
Loading dose: 24 0 mg/m
2
I.V.
24 0 mg/m
2
into pump prime volume
50 mg/m
2
/hour continuous I.V. infusion during surgery.
Lower doses of 28 mg/m
2
/hour I.V. have been ... rate.
1
The short context-sensitive half-time of
propofol, even with prolonged periods of infusion, makes it the drug
of choice for producing I.V. “conscious sedation” as...
Handbook of Pediatric Cardiovascular Drugs - part 9 pps
... the S-enantiomer of medetomidine and
is chemically described as (+ )-4 -( S )-[ 1-( 2, 3-dimethylphenyl) ethyl ]-1 H-
imidazole monohydrochloride. The active ingredient is dexmedetomidine,
12. Sedative ... Davis
Table 1 2- 5 . Onset of action and metabolism of inhalation anesthetics
Inhalation anesthetic Halothane Sevoflurane Isoflurane Desflurane
Onset of action (min)...
Handbook of Pediatric Cardiovascular Drugs - part 10 pps
... 21 0 21 2
daclizumab, 21 2 21 3
Anticoagulants
alteplase, 24 8 25 0
aminocaproic acid, 25 1 25 2
aprotinin, 25 2 25 5
argatroban, 25 5 25 7
aspirin, 25 7 26 0
clopidogrel, 26 0 26 2
dipyridamole, 26 2 26 4
enoxaparin, 26 4 26 7
heparin, ... clearing
diuretics/ranitidine/nitroglycerin/
amrinone/milrinone/
neuromuscular-blocking agents
and, 21 5
ECMO and, 21 5 22 2
gentamicin/vanco...
handbook of extractive metallurgy IV Part 2 ppt
... class="bi x7 y0 wb h0" alt=""
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