Handbook of Pediatric Cardiovascular Drugs - part 1 docx
Handbook of Pediatric Cardiovascular Drugs - part 1 docx
... incidence of serious drug-drug interac-
tions in pediatric patients receiving chronic antiepilepsy drugs.
12
Implications of CYP-450 Drug-Drug Interactions of Cardiovascular Drugs
The CYP-450 system ... effects.
1
Protein-Binding Effects
Drugs in plasma bind to proteins, including albumin, -1 -acid- glycoprotein
( -1 -AG), and lipoproteins. Albumin is the major serum p...
Handbook of Pediatric Cardiovascular Drugs - part 6 docx
... for 7 to 14 days
Atgam An intradermal skin test of Atgam is recommended before administra-
tion of the initial dose; use 0 .1 mL of a 1: 1000 dilution in NS; observe the skin
test every 15 minutes ... QT syndrome. Pediatr Int
2006;48(2) :11 2 11 7.
18 6 A.M. Dubin
Mechanism of Action
Magnesium sulfate suppresses early after-depolarizations that can trigger tor-
sade de pointes....
Handbook of Pediatric Cardiovascular Drugs - part 2 ppt
... the age
HR
- Fluid restriction
- Diuretics
- Venous
vasodilators
- Arrhuthmia?
- Rule out {{ JET }}
- Anti-arrthythimic druge
- Pacemaler
- Cardioversion
Preload
Figure 3-4 . Treatment of acute ... µg/kg/day
5 10 yr 20–30 µg/kg 5 10 µg/kg/day 15 –30 µg/kg 4–8 µg/kg/day
> ;10 yr 10 15 µg/kg 2.5–5 µg/kg/day 6 12 µg/kg 2–3 µg/kg/day
Adults 0.75 1. 5 mg...
Handbook of Pediatric Cardiovascular Drugs - part 4 ppsx
... onset of action of approximately 1 hour and a duration of
action of 12 to 24 hours. Oral absorption of the drug is dependent on the prepa-
ration used, and protein binding is 95%. The half-life ... osteomyeli-
tis after short-term prostaglandin E1 infusion. Eur J Pediatr 19 96; 15 5(3) :17 3 17 4.
Miscellaneous Agents: Hydralazine
Indication
Management of moderate to severe...
Handbook of Pediatric Cardiovascular Drugs - part 5 pdf
... (MERIT-HF).
Lancet 353( 916 9): 20 01 2007.
11 . Shaddy RE, Olsen SL, Bristow MR, et al. (19 95). Efficacy and safety of metoprolol
in the treatment of doxorubicin-induced cardiomyopathy in pediatric ... inhibitor of β
1
- adrenergic
receptors with no intrinsic sympathomimetic activity and weak membrane-
stabilizing activity.
14
Its β-selectivity is approximately 75-fold...
Handbook of Pediatric Cardiovascular Drugs - part 7 pot
... Pharmacotherapy 19 91; 11 (1) :
26–37.
12 . Wilde M, Goa K. Muromonab CD3: a reappraisal of its pharmacology and use as
prophylaxis of solid organ transplant rejection. Drugs 19 96; 51( 5): 865–894.
13 . Pittock ... surgery. Anesthesiology 19 94; 81: 616 –622.
30. Bogaert WA, Herregods LL, Mortierr EP. Cardiopulmonary bypass and pharmacoki-
netics of drugs. Clin Pharmacokinet...
Handbook of Pediatric Cardiovascular Drugs - part 8 pdf
... packaging.
Propofol is an isotonic emulsion with a pH of 7 to 8.5 and a pKa of 11 .
Propofol injectable emulsion is available in ready to use 20-mL, 50-mL, and
10 0-mL infusion vials containing 10 mg/mL ... based on INR
INR Dose
1. 1 1. 4 Increase dose by 20% of previous dose
1. 5 1. 9 Increase dose by 10 % of previous dose
2–3 Do not change the dose
3 .1 3.5 Decrease dose by...
Handbook of Pediatric Cardiovascular Drugs - part 9 pps
... effect of etomidate is a reversible,
dose-dependent inhibition of the enzyme 1 1- -hydroxylase, which converts
11 -deoxycortisol to cortisol, and a minor inhibitory effect on enzyme 1 7-
α-hydroxylase. ... relatively small, with the larg-
est including 214 participants, and the agents evaluated include simvastatin,
11 ,12
lovastatin,
13 ,14
pravastatin,
15 ,16
and ato...
Handbook of Pediatric Cardiovascular Drugs - part 10 pps
... (Continued)
antimetabolites, 19 0, 19 1, 19 8–202
AZA, 19 0, 19 1, 19 8–200
mycophenolate mofetil, 19 0, 19 1,
200–202
CNIs, 19 0, 19 3 19 8
cyclosporine, 19 0, 19 1, 19 3 19 6
tacrolimus, 19 0, 19 1, 19 6 19 8
corticosteroids, ... 15 8 16 0
class IC, 16 0 16 3
flecainide, 16 0 16 1
propafenone, 16 1 16 3
class II (β-blockers), 16 3 17 0
atenolol, 16 6 16 7
esmolol, 16...
Handbook of Advanced Interventional Cardiology - part 1 docx
... published 20 01
Second edition 2003
Reprinted 2005
ISBN -1 3 : 97 8 -1 -4 05 1- 1 73 1- 9
ISBN -1 0 : 1- 4 05 1- 1 73 1- 1
Library of Congress Cataloging-in-Publication data
Pra ct ica l ha nd b oo k of a dva nc ed ... index.
ISBN -1 3 : 97 8 -1 -4 05 1- 1 73 1- 9
ISBN -1 0 : 1- 4 05 1- 1 73 1- 1
1. Heart – Surgery. 2. Heart – Endoscopic surgery. 3. Heart
– Di seas...
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