Báo cáo y học: " Binding of long-chain α-neurotoxin would stabilize the resting state of nAChR: A comparative study with α-conotoxin" docx

... 2002 Soluble silk-like organic matrix in the nacreous layer of the bivalve Pinctada maxima A new insight in the biomineralization field Lucilia Pereira-Mourie ` s 1 , Maria-Jose ´ Almeida 1,3 , ... Amino acid compositions (mole percent) of the water -soluble matrix, water-insoluble matrix, the EDTA -soluble matrix and the EDTA- insoluble...

Ngày tải lên: 21/02/2014, 01:21

... 2002 BIGH3 (TGFBI) Arg124 mutations in uence the amyloid conversion of related peptides in vitro Implications in the BIGH3- linked corneal dystrophies Clair-Florent Schmitt-Bernard 1,2 , Alain Chavanieu 3 , ... decrease in the formation of amyloid fibrils, suggesting the importance of the hydropho- bic NH 2 -end of the peptides. In...

Ngày tải lên: 21/02/2014, 01:21

... carotenoid pathway to b-carot ene proceeds via three enzymatic steps carried out by the enzymes phytoene synthase, phytoene dehydrogenase and lycopene cyclase. The enzyme phytoene dehydrogenase is able ... organi- zation of the P. blakesleeanus phytoene dehydrogenase. Keywords: carotenoid; phytoene dehydrogenase; i nterallelic complementation; Phycomyc es blakesle...

Ngày tải lên: 22/02/2014, 04:20

... Ó FEBS 2002 S -Decyl-glutathione nonspecifically stimulates the ATPase activity of the nucleotide-binding domains of the human multidrug resistance-associated protein, MRP1 (ABCC1) Robbert H. ... m M of S-decyl-glutathione, the meas- ured ATPase activity represented approximately the basal ATPase activity. This type of behaviour was also obs...

Ngày tải lên: 17/03/2014, 23:20

... capacity to drive the key pathways typically associated with the pathogen- esis of OA. As shown here, as well as by others, IL-1 abruptly shifts the metabolism of the chondrocyte stimulating the expression ... Given the breadth of chondroprotection provided by glucosamine as shown here, it is likely that these signaling pathways also are functionally blocked by glucosamin...

Ngày tải lên: 09/08/2014, 08:23

... properly cited. Abstract The aim of the present study was to evaluate the relative contribution of human leukocyte antigen (HLA)-C locus alleles in determining the risk and the clinical expression of ... additional arthritogenic risk. HLA-C alleles may modulate some aspects of the clinical expression of PsA, but these findings need confirmation. Introdu...

Ngày tải lên: 09/08/2014, 08:23

... 1 Research article Serum keratan sulfate transiently increases in the early stage of osteoarthritis during strenuous running of rats: protective effect of intraarticular hyaluronan injection Tao Tang 1 , ... not induce the repair of osteochondral defect. Interestingly, remarkably strong staining for hyaluronan was demonstrated in areas that were...

Ngày tải lên: 09/08/2014, 10:22

... 5 of 9 RESEARC H Open Access Conserved charged amino acid residues in the extracellular region of sodium /iodide symporter are critical for iodide transport activity Chia-Cheng Li 1† , Tin-Yun ... extracellular region of NIS has been demonstrated to be critical for iodide transport in our previous study. The conserved charged amino...

Ngày tải lên: 10/08/2014, 05:21

... 4 CAS E REP O R T Open Access Cardiac tamponade mimicking tuberculous pericarditis as the initial presentation of chronic lymphocytic leukemia in a 58-year-old woman: a case report Elaine Lin 1 , ... as an incidental laboratory finding. Although leukemias represent only about eight percent of neoplastic metastases to the heart, almost 50% of lymp...

Ngày tải lên: 11/08/2014, 03:21

... 4 CAS E REP O R T Open Access Cardiac tamponade mimicking tuberculous pericarditis as the initial presentation of chronic lymphocytic leukemia in a 58-year-old woman: a case report Elaine Lin 1 , ... mimicking tuberculous pericarditis as the initial presentation of chronic lymphocytic leukemia in a 58-year-old woman: a case...

Ngày tải lên: 11/08/2014, 07:20

... Olanzapine monotherapy and olanzapine combination therapy in the treatment of mania: 12-week results from the European Mania in Bipolar Longitudinal Evaluation of Medication (EMBLEM) observational ... 1 of 9 (page number not for citation purposes) BMC Psychiatry Open Access Research article Mixed states vs. pure mania in the french sample of t...

Ngày tải lên: 11/08/2014, 17:20

... Autophagy activation was evaluated by quantifying the fluorescence intensity of LysoTracker™ Red staining of blood mononuclear cells. Mitophagy was confirmed by measuring citrate synthase activity and ... of autophagic genes and the elimination of dysfunctional mitochondria with mitophagy. Conclusions: These findings may support the role of oxidative stress an...

Ngày tải lên: 12/08/2014, 11:22

... al.: Cysteine 95 and other residues influence the regulatory effects of Histidine 69 mutations on Human Immunodeficiency Virus Type 1 protease autoprocessing. Retrovirology 2010 7:24. Submit your ... Retrovirology 2010, 7:24 http://www.retrovirology.com/content/7/1/24 Page 6 of 8 RESEA R C H Open Access Cysteine 95 and other residues influence the...

Ngày tải lên: 12/08/2014, 23:23

... 7:73 http://www.retrovirology.com/content/7 /1/ 73 Page 10 of 12 RESEARC H Open Access Mutations in matrix and SP1 repair the packaging specificity of a Human Immunodeficiency Virus Type 1 mutant by reducing the association of Gag with spliced viral ... the packaging of spliced viral RNA in SL1 mutants [11 ,14 ,34,40,45]. Des...

Ngày tải lên: 13/08/2014, 01:20

... of nAChR: A comparative study with α-conotoxin Adak Nasiripourdori, Bijan Ranjbar* and Hossein Naderi-Manesh Address: Department of Biophysics, Faculty of Science, Tarbiat Modares University, ... rearrangements associated with agonist binding propagate through beta strands to the pore domain [35-37]. By analogy with the AChBP in the resting state of the mus...

Ngày tải lên: 13/08/2014, 16:21