Báo cáo y học: " Assessing drug distribution in tissues expressing P-glycoprotein through physiologically based pharmacokinetic modeling: model structure and parameters determination" pps

... 2002 Antimicrobial peptide expression in shrimp (Eur. J. Biochem. 269) 2687 Expression and distribution of penaeidin antimicrobial peptides are regulated by haemocyte reactions in microbial challenged ... of a coating, by released penaeidin, of the bacteria before their internalization into penaeidin- devoid hyaline cells. Finally, the diversity,...

Ngày tải lên: 18/03/2014, 01:20

... purposes) Annals of General Psychiatry Open Access Primary research Assessing post-traumatic stress disorder in South African adolescents: using the child and adolescent trauma survey (CATS) as a screening ... and posttraumatic stress symptoms in adolescents. Southern African Journal of Child and Ado- lescent Mental Health 2000, 12:38-44. 13....

Ngày tải lên: 08/08/2014, 21:20

... path- ways involved in cytokine/chemokine activity (cytokine- cytokine receptor interaction and Jak-STAT signalling), matrix remodelling (focal adhesion, TGF-β signalling, and ECM receptor interaction), ... inhibi- tion prevents proinflammatory cytokine-induced cartilage damage. Rheumatology (Oxford) 2002, 41:801-808. 12. Tak PP: Chemokine inhibition in inflammatory arthritis. Best Prac...

Ngày tải lên: 09/08/2014, 01:22

... important initial information of QOL change for women in the HAART era. In summary, we evaluated the effects of HAART on QOL among women in the WIHS. HAART did not show any long-term effect on QOL changes, ... baseline. Discussion In our study, we attempted to obtain unbiased estimates of HAART effects on QOL in WIHS by minimizing indica- tion bias an...

Ngày tải lên: 10/08/2014, 05:20

... P.R. China. 2 Key Laboratory for Regenerative Medicine of Ministry of Education, Jinan University, Guangzhou, P.R. China. 3 Department of Hematology, Guangdong General Hospital (Guangdong Academy of ... to PPP2R5C, it could be interesting to analyze the expression features of PPP2R5C in hematological malignancies. In the present study, we analyzed the expression level of...

Ngày tải lên: 10/08/2014, 21:23

... manuscript. YCK, TSW, and YPL conceptualized and designed the study. YCK, TSW, and CWL collected and analyzed the data. YPL supervised the study. YCK analyzed the data further and wrote the final manuscript. ... insight in nonpsychiatric individuals and outpatients with schizophrenia in Taiwan: an investigation using the Beck Cognitive Insi...

Ngày tải lên: 11/08/2014, 16:20

... further ascertained in a clinical interview and by contacting the patient's physicians and examining medical records, attaining a final clinical symptom evaluation (FCSE). An interview yielded ... reproduction in any medium, provided the original work is properly cited. Research article Assessing medically unexplained symptoms: evaluation of a shortened ve...

Ngày tải lên: 11/08/2014, 16:22

... more on the level of standard care in South Africa rather than theefficacyoftheinterventionoffered.Also,somemay question whether such a comparatively expensive inter- vention is an appropriate way ... this article as: Botha et al.: Assessing the efficacy of a modi fied assertive community-based treatment programme in a developing country. BMC Psychiatry 2010 10...

Ngày tải lên: 11/08/2014, 16:22

... lineages on the basis of phylogenetic analyses (Table 1) [21,22]. Interestingly, only two lineages contain Vpu in their genome, the SIVcpz/HIV-1 lineage and cer- tain members of the SIVsyk lineage ... natu- rally existing prot ein from a non-human primate lenti- virus that has activity against human tetherin. Specificity of interaction between SIVsyk Vpu proteins and tetherin Since the SI...

Ngày tải lên: 12/08/2014, 23:23

... article as: Yang and Raimundo: Assessing the effects of multiple infections and long latency in the dynamics of tuberculosis. Theoretical Biology and Medical Modelling 2010 7:41. Submit your next ... TB. Our intention is to assess the effects of varying the model’s parameters in the back- ward bifurcation. We analyze the system (2) in steady states....

Ngày tải lên: 13/08/2014, 16:20

... Medical Modelling Research Assessing drug distribution in tissues expressing P-glycoprotein through physiologically based pharmacokinetic modeling: model structure and parameters determination Frédérique Fenneteau 1 , ... (PBPK): physiologically based pharmacokinetic; (P diff, invitro in dm/min): in vitro diffusion velocity of the drug through the...

Ngày tải lên: 13/08/2014, 16:21

... following the introduction of government guidelines in England David M Foreman* 1,2 and Tamsin Ford 3 Address: 1 Department of Child and Adolescent Psychiatry, Institute of Psychiatry at the ... controversy by introducing practice guidelines for the detection of hyperkinetic disorders by the National Health Service (NHS) in addition to those provided by pro...

Ngày tải lên: 13/08/2014, 18:21

... predicted body weight. Finally, the ability to interpret the fi nding that EVLW as measured by the transpulmonary thermodilution method did not correlate with EVLW assessed using the chest radiograph ... may be limited for several reasons. First, the radiographic scoring system may not have accurately refl ected the quantity of pulmonary edema. One important confounder...

Ngày tải lên: 13/08/2014, 21:21

... purposes) Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine Open Access Review Thrombelastography and tromboelastometry in assessing coagulopathy in trauma Pär I Johansson*, Trine ... tracings: A) Normal, B) Hypercoagulability, C) Hypocoagulability (throm- bocytopenia/pathy) and D) Primary hyperfibrinolysis. A D B C Scandinavian Journal of Trauma, Resus...

Ngày tải lên: 13/08/2014, 23:20

... default doses for aminoglycosides. Drug Safety 2006, 29:803-809. doi:10.1186/cc9366 Cite this article as: Carson-Stevens A, et al.: Minimising drug errors in critically ill patients. Critical ... SE, Klazinga NS, Guchelaar HJ, Smorenburg SM: Application of the bow-tie model in medication safety risk analysis consecutive experience in two hospitals in the Netherlands. Dru...

Ngày tải lên: 14/08/2014, 07:21